BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND DNMT3A, Q9Y6K1, 1788, ENSG00000119772, DNMT3A2, M_HsaIIIA
28 results:

  • 1. dnmt3a Cooperates with YAP/TAZ to Drive Gallbladder cancer Metastasis.
    Xu S; Yuan Z; Jiang C; Chen W; Li Q; Chen T
    Adv Sci (Weinh); 2024 Apr; 11(16):e2308531. PubMed ID: 38380551
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Altered DNA methylation within dnmt3a, AHRR, LTA/TNF loci mediates the effect of smoking on inflammatory bowel disease.
    Zhang H; Kalla R; Chen J; Zhao J; Zhou X; Adams A; Noble A; Ventham NT; Wellens J; Ho GT; Dunlop MG; Nowak JK; Ding Y; Liu Z; Satsangi J; Theodoratou E; Li X
    Nat Commun; 2024 Jan; 15(1):595. PubMed ID: 38238335
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Targeting polycomb repressor complex 2-mediated bivalent promoter epigenetic silencing of secreted frizzled-related protein 1 inhibits cholangiocarcinoma progression.
    Wu G; Wang Q; Wang D; Xiong F; Liu W; Chen J; Wang B; Huang W; Wang X; Chen Y
    Clin Transl Med; 2023 Dec; 13(12):e1502. PubMed ID: 38050190
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Upregulation of RSPO3 via targeted promoter DNA demethylation inhibits the progression of cholangiocarcinoma.
    Wu G; Wang D; Xiong F; Liu W; Wang Q; Chen J; Wang B; Chen Y
    Clin Epigenetics; 2023 Nov; 15(1):177. PubMed ID: 37932819
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Facility type is associated with improved perioperative and oncologic outcomes after minimally invasive surgery for pancreatic cancer.
    Servin-Rojas M; Shafique N; Sell NM; Gamblin TC; Qadan M
    HPB (Oxford); 2023 Aug; 25(8):933-940. PubMed ID: 37149486
    [TBL] [Abstract] [Full Text] [Related]  

  • 6.
    Wang K; Gong D; Qiao X; Zheng J
    Life Sci Alliance; 2023 Apr; 6(5):. PubMed ID: 37085288
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Surgical Management of G3 Gastroenteropancreatic Neuroendocrine Neoplasms: A Systematic Review and Meta-analysis.
    Ziogas IA; Tasoudis PT; Borbon LC; Sherman SK; Breheny PJ; Chandrasekharan C; Dillon JS; Bellizzi AM; Howe JR
    Ann Surg Oncol; 2023 Jan; 30(1):148-160. PubMed ID: 36227392
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Integrative genomic and transcriptomic profiling reveals distinct molecular subsets in adult mixed phenotype acute leukemia.
    Wang Q; Cai WZ; Wang QR; Zhu MQ; Yan LZ; Yu Y; Bao XB; Shen HJ; Yao H; Xie JD; Zhang TT; Zhang L; Xu XY; Shan Z; Liu H; Cen JN; Liu DD; Pan JL; Lu DR; Chen J; Xu Y; Zhang R; Wang Y; Xue SL; Miao M; Han Y; Tang XW; Qiu HY; Sun AN; Huang JY; Dai HP; Wu DP; Chen SN
    Am J Hematol; 2023 Jan; 98(1):66-78. PubMed ID: 36219502
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner.
    Woods ML; Weiss A; Sokol AM; Graumann J; Boettger T; Richter AM; Schermuly RT; Dammann RH
    Cancer Gene Ther; 2022 Dec; 29(12):1975-1987. PubMed ID: 35902728
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Protein phosphatase 2A inactivation induces microsatellite instability, neoantigen production and immune response.
    Yen YT; Chien M; Wu PY; Ho CC; Ho CT; Huang KC; Chiang SF; Chao KSC; Chen WT; Hung SC
    Nat Commun; 2021 Dec; 12(1):7297. PubMed ID: 34911954
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy.
    Xu S; Jiang C; Lin R; Wang X; Hu X; Chen W; Chen X; Chen T
    J Exp Clin Cancer Res; 2021 Nov; 40(1):373. PubMed ID: 34823564
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Predictive value of m5C regulatory gene expression in pancreatic adenocarcinoma.
    Yu X; Zhang Q; Gao F; Zhang M; Zheng Q; He Y; Guo W
    Sci Rep; 2021 Sep; 11(1):17529. PubMed ID: 34471186
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Anti-oncogene PTPN13 inactivation by hepatitis B virus X protein counteracts IGF2BP1 to promote hepatocellular carcinoma progression.
    Yan Y; Huang P; Mao K; He C; Xu Q; Zhang M; Liu H; Zhou Z; Zhou Q; Zhou Q; Ou B; Liu Q; Lin J; Chen R; Wang J; Zhang J; Xiao Z
    Oncogene; 2021 Jan; 40(1):28-45. PubMed ID: 33051595
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Nicotine induces aberrant hypermethylation of tumor suppressor genes in pancreatic epithelial ductal cells.
    Jin T; Hao J; Fan D
    Biochem Biophys Res Commun; 2018 May; 499(4):934-940. PubMed ID: 29626481
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53‑deficient pancreatic cancer cells.
    Jing W; Song N; Liu Y; Qu X; Hou K; Yang X; Che X
    Mol Med Rep; 2018 Jan; 17(1):117-124. PubMed ID: 29115606
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
    Nagaraju GP; Wu C; Merchant N; Chen Z; Lesinski GB; El-Rayes BF
    Cancer Lett; 2017 Aug; 402():110-116. PubMed ID: 28583846
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Emodin enhances the demethylation by 5-Aza-CdR of pancreatic cancer cell tumor-suppressor genes P16, RASSF1A and ppENK.
    Pan FP; Zhou HK; Bu HQ; Chen ZQ; Zhang H; Xu LP; Tang J; Yu QJ; Chu YQ; Pan J; Fei Y; Lin SZ; Liu DL; Chen L
    Oncol Rep; 2016 Apr; 35(4):1941-9. PubMed ID: 26782786
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor.
    Gayet O; Loncle C; Duconseil P; Gilabert M; Lopez MB; Moutardier V; Turrini O; Calvo E; Ewald J; Giovannini M; Gasmi M; Bories E; Barthet M; Ouaissi M; Goncalves A; Poizat F; Raoul JL; Secq V; Garcia S; Viens P; Dusetti N; Iovanna J
    Oncotarget; 2015 Jan; 6(2):746-54. PubMed ID: 25481873
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Aberrant DNA methyltransferase expression in pancreatic ductal adenocarcinoma development and progression.
    Gao J; Wang L; Xu J; Zheng J; Man X; Wu H; Jin J; Wang K; Xiao H; Li S; Li Z
    J Exp Clin Cancer Res; 2013 Nov; 32(1):86. PubMed ID: 24423239
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. RNF43 mutations are recurrent in Chinese patients with mucinous ovarian carcinoma but absent in other subtypes of ovarian cancer.
    Zou Y; Wang F; Liu FY; Huang MZ; Li W; Yuan XQ; Huang OP; He M
    Gene; 2013 Nov; 531(1):112-6. PubMed ID: 24001777
    [TBL] [Abstract] [Full Text] [Related]  


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