BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND ERBB3, c-erbB3, 2065, P21860, p180-ErbB3, c-erbB-3, ErbB-3, MDA-BF-1, HER3, p85-sErbB3, MGC88033, p45-sErbB3, ENSG00000065361, erbB3-S
106 results:

  • 1. Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission.
    Yan J; Wang X; Fan Z; Xu Y; Zhang Y; Liu Y; Guo L; Liu D
    Apoptosis; 2024 Jun; 29(5-6):709-725. PubMed ID: 38459420
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer.
    Han J; Xu J; Liu Y; Liang S; LaBella KA; Chakravarti D; Spring DJ; Xia Y; DePinho RA
    Genes Dev; 2023 Sep; 37(17-18):818-828. PubMed ID: 37775182
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. AMT-562, a Novel her3-targeting Antibody-Drug Conjugate, Demonstrates a Potential to Broaden Therapeutic Opportunities for her3-expressing Tumors.
    Weng W; Meng T; Pu J; Ma L; Shen Y; Wang Z; Pan R; Wang M; Chen C; Wang L; Zhang J; Zhou B; Shao S; Qian Y; Liu S; Hu W; Meng X
    Mol Cancer Ther; 2023 Sep; 22(9):1013-1027. PubMed ID: 37302522
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. her3- A key survival pathway and an emerging therapeutic target in metastatic colorectal cancer and pancreatic ductal adenocarcinoma.
    Desai O; Wang R
    Oncotarget; 2023 May; 14():439-443. PubMed ID: 37163206
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Feasibility of Co-Targeting her3 and EpCAM Using Seribantumab and DARPin-Toxin Fusion in a pancreatic cancer Xenograft Model.
    Xu T; Schulga A; Konovalova E; Rinne SS; Zhang H; Vorontsova O; Orlova A; Deyev SM; Tolmachev V; Vorobyeva A
    Int J Mol Sci; 2023 Feb; 24(3):. PubMed ID: 36769161
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. A Phase 2 Trial of Afatinib in Patients with Solid Tumors that Harbor Genomic Aberrations in the HER family: The MOBILITY3 Basket Study.
    Salawu A; Hansen AR; Spreafico A; Al-Ezzi E; Webster S; Bedard PL; Doi J; Wang L; Siu LL; Abdul Razak AR
    Target Oncol; 2022 May; 17(3):271-281. PubMed ID: 35635640
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. In Vitro Tumor Cell-Binding Assay to Select High-Binding Antibody and Predict Therapy Response for Personalized
    Hihara F; Matsumoto H; Yoshimoto M; Masuko T; Endo Y; Igarashi C; Tachibana T; Shinada M; Zhang MR; Kurosawa G; Sugyo A; Tsuji AB; Higashi T; Kurihara H; Ueno M; Yoshii Y
    Int J Mol Sci; 2022 May; 23(10):. PubMed ID: 35628616
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  • 8. Recent Advances in Epidermal Growth Factor Receptor Inhibitors (EGFRIs) and their Role in the Treatment of cancer: A Review.
    Unnisa A; Chettupalli AK; Hussain T; Kamal MA
    Anticancer Agents Med Chem; 2022; 22(20):3370-3381. PubMed ID: 35400324
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:erbb3 Heterodimerization.
    Werr L; Plenker D; Dammert MA; Lorenz C; Brägelmann J; Tumbrink HL; Klein S; Schmitt A; Büttner R; Persigehl T; Shokat KM; Wunderlich FT; Schram AM; Peifer M; Sos ML; Reinhardt HC; Thomas RK
    Mol Cancer Ther; 2022 May; 21(5):821-830. PubMed ID: 35247925
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The significance of ErbB2/3 in the conversion of induced pluripotent stem cells into cancer stem cells.
    Hassan G; Zahra MH; Seno A; Seno M
    Sci Rep; 2022 Feb; 12(1):2711. PubMed ID: 35177646
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  • 11. Zenocutuzumab, a HER2xher3 Bispecific Antibody, Is Effective Therapy for Tumors Driven by NRG1 Gene Rearrangements.
    Schram AM; Odintsov I; Espinosa-Cotton M; Khodos I; Sisso WJ; Mattar MS; Lui AJW; Vojnic M; Shameem SH; Chauhan T; Torrisi J; Ford J; O'Connor MN; Geuijen CAW; Schackmann RCJ; Lammerts van Bueren JJ; Wasserman E; de Stanchina E; O'Reilly EM; Ladanyi M; Drilon A; Somwar R
    Cancer Discov; 2022 May; 12(5):1233-1247. PubMed ID: 35135829
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Identification of a DNA repair 9-gene signature for the overall survival prediction of pancreatic cancer.
    Huang J; Mao Q; Sun X
    Ann Diagn Pathol; 2022 Apr; 57():151883. PubMed ID: 35123152
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. The Oncogenic Signaling Disruptor, NDRG1: Molecular and Cellular Mechanisms of Activity.
    Chekmarev J; Azad MG; Richardson DR
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572031
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The potential targeted drugs for fusion genes including NRG1 in pancreatic cancer.
    Umemoto K; Sunakawa Y
    Crit Rev Oncol Hematol; 2021 Oct; 166():103465. PubMed ID: 34454058
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Screening and Validation of Independent Predictors of Poor Survival in pancreatic cancer.
    Liu S; Cai Y; Changyong E; Sheng J; Zhang X
    Pathol Oncol Res; 2021; 27():1609868. PubMed ID: 34321959
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models.
    Rabia E; Garambois V; Hubert J; Bruciamacchie M; Pirot N; Delpech H; Broyon M; Theillet C; Colombo PE; Vie N; Tosi D; Gongora C; Khellaf L; Jarlier M; Radosevic-Robin N; Chardès T; Pèlegrin A; Larbouret C
    MAbs; 2021; 13(1):1914883. PubMed ID: 33876707
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Identification of tumors with NRG1 rearrangement, including a novel putative pathogenic UNC5D-NRG1 gene fusion in prostate cancer by data-drilling a de-identified tumor database.
    Ptáková N; Martínek P; Holubec L; Janovský V; Vančurová J; Grossmann P; Navarro PA; Rodriguez Moreno JF; Alaghehbandan R; Hes O; Májek O; Pešek M; Michal M; Ondič O
    Genes Chromosomes Cancer; 2021 Jul; 60(7):474-481. PubMed ID: 33583086
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Whole-exome mutational landscape of neuroendocrine carcinomas of the gallbladder.
    Liu F; Li Y; Ying D; Qiu S; He Y; Li M; Liu Y; Zhang Y; Zhu Q; Hu Y; Liu L; Li G; Pan W; Jin W; Mu J; Cao Y; Liu Y
    Signal Transduct Target Ther; 2021 Feb; 6(1):55. PubMed ID: 33563892
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Massively parallel sequencing analysis of 68 gastric-type cervical adenocarcinomas reveals mutations in cell cycle-related genes and potentially targetable mutations.
    Selenica P; Alemar B; Matrai C; Talia KL; Veras E; Hussein Y; Oliva E; Beets-Tan RGH; Mikami Y; McCluggage WG; Kiyokawa T; Weigelt B; Park KJ; Murali R
    Mod Pathol; 2021 Jun; 34(6):1213-1225. PubMed ID: 33318584
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of antagonistic combinations: Implications for future clinical trials in pancreatic cancer.
    Khan T; Seddon AM; Dalgleish AG; Khelwatty S; Ioannou N; Mudan S; Modjtahedi H
    Oncol Rep; 2020 Dec; 44(6):2581-2594. PubMed ID: 33125153
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