Terms: = Pancreatic cancer AND EZH2, ENX-1, 2146, ENSG00000106462, Q15910, MGC9169 AND Treatment
42 results:
1. ezh2 as a potential therapeutic target for gastrointestinal cancers.
Hashemi M; Nazdari N; Gholamiyan G; Paskeh MDA; Jafari AM; Nemati F; Khodaei E; Abyari G; Behdadfar N; Raei B; Raesi R; Nabavi N; Hu P; Rashidi M; Taheriazam A; Entezari M
Pathol Res Pract; 2024 Jan; 253():154988. PubMed ID: 38118215
[TBL] [Abstract] [Full Text] [Related]
2. Targeting polycomb repressor complex 2-mediated bivalent promoter epigenetic silencing of secreted frizzled-related protein 1 inhibits cholangiocarcinoma progression.
Wu G; Wang Q; Wang D; Xiong F; Liu W; Chen J; Wang B; Huang W; Wang X; Chen Y
Clin Transl Med; 2023 Dec; 13(12):e1502. PubMed ID: 38050190
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3. Design, Synthesis, and Biological Evaluation of a Potent Dual ezh2-BRD4 Inhibitor for the treatment of Some Solid Tumors.
Huang N; Liao P; Zuo Y; Zhang L; Jiang R
J Med Chem; 2023 Feb; 66(4):2646-2662. PubMed ID: 36774555
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4. TGF-β1/Smad3 upregulates UCA1 to promote liver fibrosis through DKK1 and miR18a.
Yang Z; Zhang H; Yin M; Cheng Z; Jiang P; Feng M; Liu Z; Liao B
J Mol Med (Berl); 2022 Oct; 100(10):1465-1478. PubMed ID: 36001113
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5. Design and Synthesis of Dual ezh2/BRD4 Inhibitors to Target Solid Tumors.
Guo Z; Sun Y; Liang L; Lu W; Luo B; Wu Z; Huo B; Hu Y; Huang P; Wu Q; Wen S
J Med Chem; 2022 May; 65(9):6573-6592. PubMed ID: 35500243
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6. SOX8 Affects Tumoral SPARC Expression by Regulating ezh2 to Attenuate Effectiveness of albumin-bound paclitaxel in PDAC.
Yuan S; Xu J; Zhou B; Zhou Y; Lang M; Cao J; Liu Z; Yang S; Gao S; Hao J
Int J Biol Sci; 2022; 18(3):911-922. PubMed ID: 35173526
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7. A novel RNA binding protein-associated prognostic model to predict overall survival in hepatocellular carcinoma patients.
Liu Y; Liu X; Gu Y; Lu H
Medicine (Baltimore); 2021 Jul; 100(29):e26491. PubMed ID: 34398005
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8. MicroRNA-506-3p inhibits colorectal cancer cell proliferation through targeting enhancer of zeste homologue 2.
Ai L; Luo X; Yan X; Jiang S
Bioengineered; 2021 Dec; 12(1):4044-4053. PubMed ID: 34288823
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9. Tumor-derived exosomal long noncoding RNA LINC01133, regulated by Periostin, contributes to pancreatic ductal adenocarcinoma epithelial-mesenchymal transition through the Wnt/β-catenin pathway by silencing AXIN2.
Liu Y; Tang T; Yang X; Qin P; Wang P; Zhang H; Bai M; Wu R; Li F
Oncogene; 2021 Apr; 40(17):3164-3179. PubMed ID: 33824474
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10. KDM2B is involved in the epigenetic regulation of TGF-β-induced epithelial-mesenchymal transition in lung and pancreatic cancer cell lines.
Wanna-Udom S; Terashima M; Suphakhong K; Ishimura A; Takino T; Suzuki T
J Biol Chem; 2021; 296():100213. PubMed ID: 33779563
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11. Coordinated silencing of the Sp1-mediated long noncoding RNA MEG3 by ezh2 and HDAC3 as a prognostic factor in pancreatic ductal adenocarcinoma.
Han T; Zhuo M; Yuan C; Xiao X; Cui J; Qin G; Wang L; Jiao F
Cancer Biol Med; 2020 Nov; 17(4):953-969. PubMed ID: 33299646
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12. LncRNA STXBP5-AS1 suppresses stem cell-like properties of pancreatic cancer by epigenetically inhibiting neighboring androglobin gene expression.
Chen S; Huang L; Li G; Qiu F; Wang Y; Yang C; Pan J; Wu Z; Chen J; Tian Y
Clin Epigenetics; 2020 Nov; 12(1):168. PubMed ID: 33160411
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13. Epigenetic silencing of CDKN1A and CDKN2B by SNHG1 promotes the cell cycle, migration and epithelial-mesenchymal transition progression of hepatocellular carcinoma.
Li B; Li A; You Z; Xu J; Zhu S
Cell Death Dis; 2020 Oct; 11(10):823. PubMed ID: 33009370
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14. LncRNA LEF1-AS1 silencing diminishes ezh2 expression to delay hepatocellular carcinoma development by impairing CEBPB-interaction with CDCA7.
Gao J; Dai C; Yu X; Yin XB; Zhou F
Cell Cycle; 2020 Apr; 19(8):870-883. PubMed ID: 32178558
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15. ezh2 Downregulation Augments the Effect of Irradiation in Reducing pancreatic cancer Cell Proliferation
Agrawal R; Chen M; Bukhari Z; Ogunwobi OO; Haseeb MA; Martello LA
Ann Clin Lab Sci; 2020 Jan; 50(1):45-56. PubMed ID: 32161011
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16. Downregulation of long noncoding RNA SNHG14 suppresses cell proliferation and invasion by regulating ezh2 in pancreatic ductal adenocarcinoma (PDAC).
Xie F; Huang Q; Wang C; Chen S; Liu C; Lin X; Lv X; Wang C
Cancer Biomark; 2020; 27(3):357-364. PubMed ID: 31929143
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17. Diosgenin exhibits tumor suppressive function via down-regulation of ezh2 in pancreatic cancer cells.
Guo W; Chen Y; Gao J; Zhong K; Wei H; Li K; Tang M; Zhao X; Liu X; Nie C; Yuan Z
Cell Cycle; 2019 Aug; 18(15):1745-1758. PubMed ID: 31213123
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18. RREB1-induced upregulation of the lncRNA AGAP2-AS1 regulates the proliferation and migration of pancreatic cancer partly through suppressing ANKRD1 and ANGPTL4.
Hui B; Ji H; Xu Y; Wang J; Ma Z; Zhang C; Wang K; Zhou Y
Cell Death Dis; 2019 Feb; 10(3):207. PubMed ID: 30814490
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19. Epigenetic Co-Deregulation of ezh2/TET1 is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast cancer.
Yu Y; Qi J; Xiong J; Jiang L; Cui D; He J; Chen P; Li L; Wu C; Ma T; Shao S; Wang J; Yu D; Zhou B; Huang D; Schmitt CA; Tao R
Theranostics; 2019; 9(3):761-777. PubMed ID: 30809307
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20. ezh2-Mediated microRNA-139-5p Regulates Epithelial-Mesenchymal Transition and Lymph Node Metastasis of pancreatic cancer.
Ma J; Zhang J; Weng YC; Wang JC
Mol Cells; 2018 Sep; 41(9):868-880. PubMed ID: 30304920
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