Terms: = Pancreatic cancer AND IDH2, P48735, 3418, ENSG00000182054, IDHM, mNADP-IDH, IDH, IDP, ICD-M
35 results:
1. APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S; Li Y; Xu J; Shen L
Neurol Res; 2024 Mar; 46(3):227-242. PubMed ID: 38007705
[TBL] [Abstract] [Full Text] [Related]
2. Hypoxia-Inducible Factor 2 Alpha (HIF2α) Inhibitors: Targeting Genetically Driven Tumor Hypoxia.
Toledo RA; Jimenez C; Armaiz-Pena G; Arenillas C; Capdevila J; Dahia PLM
Endocr Rev; 2023 Mar; 44(2):312-322. PubMed ID: 36301191
[TBL] [Abstract] [Full Text] [Related]
3. A Novel Prognostic Signature Revealed the Interaction of Immune Cells in Tumor Microenvironment Based on Single-Cell RNA Sequencing for Lung Adenocarcinoma.
Jin X; Hu Z; Sui Q; Zhao M; Liang J; Liao Z; Zheng Y; Wang H; Shi Y
J Immunol Res; 2022; 2022():6555810. PubMed ID: 35812244
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4. Laparoscopic liver resection can be performed safely without intraoperative drain placement.
Sugimoto M; Gotohda N; Kudo M; Kobayashi S; Takahashi S; Konishi M
Surg Endosc; 2022 Dec; 36(12):9019-9031. PubMed ID: 35680665
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5. Isocitrate Dehydrogenase-Mutated Cholangiocarcinoma: Natural History and Clinical Outcomes.
Wintheiser G; Zemla T; Shi Q; Tran N; Prasai K; Tella SH; Mody K; Ahn D; Borad M; Bekaii-Saab T; Mahipal A
JCO Precis Oncol; 2022 Jan; 6():e2100156. PubMed ID: 35005992
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6. Epigenetic upregulation of TET2 is an independent poor prognostic factor for intrahepatic cholangiocarcinoma.
Yamashita H; Tourna A; Akita M; Itoh T; Chokshi S; Ajiki T; Fukumoto T; Youngson NA; Zen Y
Virchows Arch; 2022 May; 480(5):1077-1085. PubMed ID: 34905094
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7. Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function.
Rizzuti B; Lan W; Santofimia-Castaño P; Zhou Z; Velázquez-Campoy A; Abián O; Peng L; Neira JL; Xia Y; Iovanna JL
Biomolecules; 2021 Oct; 11(10):. PubMed ID: 34680086
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8. Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Hwang MS; Miller MS; Thirawatananond P; Douglass J; Wright KM; Hsiue EH; Mog BJ; Aytenfisu TY; Murphy MB; Aitana Azurmendi P; Skora AD; Pearlman AH; Paul S; DiNapoli SR; Konig MF; Bettegowda C; Pardoll DM; Papadopoulos N; Kinzler KW; Vogelstein B; Zhou S; Gabelli SB
Nat Commun; 2021 Sep; 12(1):5271. PubMed ID: 34489470
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9. A pan-cancer perspective analysis reveals the opposite prognostic significance of CD133 in lower grade glioma and papillary renal cell carcinoma.
Wang H; Wang X; Xu L; Zhang J; Cao H
Sci Prog; 2021; 104(2):368504211010938. PubMed ID: 33878963
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10. New and Emerging Systemic Therapeutic Options for Advanced Cholangiocarcinoma.
Massironi S; Pilla L; Elvevi A; Longarini R; Rossi RE; Bidoli P; Invernizzi P
Cells; 2020 Mar; 9(3):. PubMed ID: 32168869
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11. Mutant idh1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation.
Fujiwara H; Tateishi K; Misumi K; Hayashi A; Igarashi K; Kato H; Nakatsuka T; Suzuki N; Yamamoto K; Kudo Y; Hayakawa Y; Nakagawa H; Tanaka Y; Ijichi H; Kogure H; Nakai Y; Isayama H; Hasegawa K; Fukayama M; Soga T; Koike K
Sci Rep; 2019 Dec; 9(1):18859. PubMed ID: 31827136
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12. Targeting the Stress-Induced Protein NUPR1 to Treat pancreatic Adenocarcinoma.
Santofimia-Castaño P; Xia Y; Peng L; Velázquez-Campoy A; Abián O; Lan W; Lomberk G; Urrutia R; Rizzuti B; Soubeyran P; Neira JL; Iovanna J
Cells; 2019 Nov; 8(11):. PubMed ID: 31744261
[TBL] [Abstract] [Full Text] [Related]
13. Targeting intrinsically disordered proteins involved in cancer.
Santofimia-Castaño P; Rizzuti B; Xia Y; Abian O; Peng L; Velázquez-Campoy A; Neira JL; Iovanna J
Cell Mol Life Sci; 2020 May; 77(9):1695-1707. PubMed ID: 31667555
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14. Systemic screening identifies GABRD, a subunit gene of GABAA receptor as a prognostic marker in adult idh wild-type diffuse low-grade glioma.
Zhang H; Zhang L; Tang Y; Wang C; Chen Y; Shu J; Zhang K
Biomed Pharmacother; 2019 Oct; 118():109215. PubMed ID: 31545245
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15. Metabolic profiling reveals distinct metabolic alterations in different subtypes of pituitary adenomas and confers therapeutic targets.
Feng J; Gao H; Zhang Q; Zhou Y; Li C; Zhao S; Hong L; Yang J; Hao S; Hong W; Zhuang Z; Xu G; Zhang Y
J Transl Med; 2019 Aug; 17(1):291. PubMed ID: 31455412
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16. Anti-Apoptotic and Anti-Oxidant Proteins in Glioblastomas: Immunohistochemical Expression of Beclin and DJ-1 and Its Correlation with Prognosis.
Guadagno E; Borrelli G; Pignatiello S; Donato A; Presta I; Arcidiacono B; Malara N; Solari D; Somma T; Cappabianca P; Donato G; Del Basso De Caro M
Int J Mol Sci; 2019 Aug; 20(16):. PubMed ID: 31434323
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17. The cancer driver genes idh1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Chang S; Yim S; Park H
Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
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18. Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.
Santofimia-Castaño P; Xia Y; Lan W; Zhou Z; Huang C; Peng L; Soubeyran P; Velázquez-Campoy A; Abián O; Rizzuti B; Neira JL; Iovanna J
J Clin Invest; 2019 Mar; 129(6):2500-2513. PubMed ID: 30920390
[TBL] [Abstract] [Full Text] [Related]
19. Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gallbladder, and Extrahepatic Biliary Tract: 2018 Update.
Zhang L; Bluth MH; Bhalla A
Clin Lab Med; 2018 Jun; 38(2):367-384. PubMed ID: 29776636
[TBL] [Abstract] [Full Text] [Related]
20. Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1).
Santofimia-Castaño P; Rizzuti B; Abián O; Velázquez-Campoy A; Iovanna JL; Neira JL
Biochim Biophys Acta Gen Subj; 2018 Jun; 1862(6):1283-1295. PubMed ID: 29530795
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