Terms: = Pancreatic cancer AND JAK1, ENSG00000162434, P23458, JTK3, JAK1B, JAK1A, 3716 AND Treatment
21 results:
1. PI3K Inhibition Restores and Amplifies Response to Ruxolitinib in Patients with Myelofibrosis.
Moyo TK; Kishtagari A; Villaume MT; McMahon B; Mohan SR; Stopczynski T; Chen SC; Fan R; Huo Y; Moon H; Tang Y; Bejan CA; Childress M; Anderson I; Rawling K; Simons RM; Moncrief A; Caza R; Dugger L; Collins A; Dudley CV; Ferrell PB; Byrne M; Strickland SA; Ayers GD; Landman BA; Mason EF; Mesa RA; Palmer JM; Michaelis LC; Savona MR
Clin Cancer Res; 2023 Jul; 29(13):2375-2384. PubMed ID: 37036505
[TBL] [Abstract] [Full Text] [Related]
2. Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the treatment of pancreatic Adenocarcinoma.
Di Giorgio C; Lupia A; Marchianò S; Bordoni M; Bellini R; Massa C; Urbani G; Roselli R; Moraca F; Sepe V; Catalanotti B; Morretta E; Monti MC; Biagioli M; Distrutti E; Zampella A; Fiorucci S
Cells; 2022 Nov; 11(21):. PubMed ID: 36359879
[TBL] [Abstract] [Full Text] [Related]
3. IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer.
He Y; Luo W; Liu Y; Wang Y; Ma C; Wu Q; Tian P; He D; Jia Z; Lv X; Ma YS; Yang H; Xu K; Zhang X; Xiao Y; Zhang P; Liang Y; Fu D; Yao F; Hu G
J Clin Invest; 2022 Oct; 132(20):. PubMed ID: 36006737
[TBL] [Abstract] [Full Text] [Related]
4. Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells.
Leung SS; Borg DJ; McCarthy DA; Boursalian TE; Cracraft J; Zhuang A; Fotheringham AK; Flemming N; Watkins T; Miles JJ; Groop PH; Scheijen JL; Schalkwijk CG; Steptoe RJ; Radford KJ; Knip M; Forbes JM
Diabetes; 2022 Sep; 71(9):1994-2008. PubMed ID: 35713929
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5. Laparoscopic liver resection for colorectal liver metastases: retrospective analysis of prognostic factors and oncological outcomes in a single-center cohort.
Taillieu E; De Meyere C; Nuytens F; Vanneste G; Libbrecht L; Alaerts H; Parmentier I; Verslype C; D'Hondt M
Langenbecks Arch Surg; 2022 Sep; 407(6):2399-2414. PubMed ID: 35499586
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6. The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and jak1/Stat3 signaling.
Safari F; Shafiee Nejad N; Aghaei Nejad A
Med Oncol; 2022 Jan; 39(3):28. PubMed ID: 35059869
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7. IL-10 derived from Hepatocarcinoma cells improves human induced regulatory T cells function via jak1/STAT5 pathway in tumor microenvironment.
Zhang S; Gan X; Qiu J; Ju Z; Gao J; Zhou J; Shi C; Zhu Y; Li Z
Mol Immunol; 2021 May; 133():163-172. PubMed ID: 33667986
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8. LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway.
Jung YY; Ko JH; Um JY; Chinnathambi A; Alharbi SA; Sethi G; Ahn KS
J Cell Physiol; 2021 Jul; 236(7):5253-5264. PubMed ID: 33368314
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9. Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma.
Grant RC; Denroche R; Jang GH; Nowak KM; Zhang A; Borgida A; Holter S; Topham JT; Wilson J; Dodd A; Jang R; Prince R; Karasinska JM; Schaeffer DF; Wang Y; Zogopoulos G; Berry S; Simeone D; Renouf DJ; Notta F; O'Kane G; Knox J; Fischer S; Gallinger S
Gut; 2021 Oct; 70(10):1894-1903. PubMed ID: 32933947
[TBL] [Abstract] [Full Text] [Related]
10. microRNA-1225 inhibit apoptosis of pancreatic cancer cells via targeting jak1.
Zhong R; Li S; Fang K; Yang L; Wang L
Cell Cycle; 2019 May; 18(9):990-1000. PubMed ID: 30990343
[TBL] [Abstract] [Full Text] [Related]
11. A Phase Ib/II Study of the jak1 Inhibitor, Itacitinib, plus
Beatty GL; Shahda S; Beck T; Uppal N; Cohen SJ; Donehower R; Gabayan AE; Assad A; Switzky J; Zhen H; Von Hoff DD
Oncologist; 2019 Jan; 24(1):14-e10. PubMed ID: 30115734
[TBL] [Abstract] [Full Text] [Related]
12. Momelotinib therapy for myelofibrosis: a 7-year follow-up.
Tefferi A; Barraco D; Lasho TL; Shah S; Begna KH; Al-Kali A; Hogan WJ; Litzow MR; Hanson CA; Ketterling RP; Gangat N; Pardanani A
Blood Cancer J; 2018 Mar; 8(3):29. PubMed ID: 29515114
[TBL] [Abstract] [Full Text] [Related]
13. pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors.
Al-Hader A; Al-Rohil RN; Han H; Von Hoff D
World J Gastroenterol; 2017 Dec; 23(45):7945-7951. PubMed ID: 29259370
[TBL] [Abstract] [Full Text] [Related]
14. Ruxolitinib and Polycation Combination treatment Overcomes Multiple Mechanisms of Resistance of pancreatic cancer Cells to Oncolytic Vesicular Stomatitis Virus.
Felt SA; Droby GN; Grdzelishvili VZ
J Virol; 2017 Aug; 91(16):. PubMed ID: 28566376
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15. Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo.
Komar HM; Serpa G; Kerscher C; Schwoegl E; Mace TA; Jin M; Yang MC; Chen CS; Bloomston M; Ostrowski MC; Hart PA; Conwell DL; Lesinski GB
Sci Rep; 2017 May; 7(1):1787. PubMed ID: 28496202
[TBL] [Abstract] [Full Text] [Related]
16. Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in pancreatic cancer.
Smigiel JM; Parameswaran N; Jackson MW
Mol Cancer Res; 2017 Apr; 15(4):478-488. PubMed ID: 28053127
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17. Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus.
Hastie E; Cataldi M; Moerdyk-Schauwecker MJ; Felt SA; Steuerwald N; Grdzelishvili VZ
Oncotarget; 2016 Sep; 7(38):61601-61618. PubMed ID: 27533247
[TBL] [Abstract] [Full Text] [Related]
18. Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells.
Xu Q; Fu R; Yin G; Liu X; Liu Y; Xiang M
Gene; 2016 Mar; 578(2):263-73. PubMed ID: 26719042
[TBL] [Abstract] [Full Text] [Related]
19. Blockage of STAT3 Signaling Pathway by Morusin Induces Apoptosis and Inhibits Invasion in Human pancreatic Tumor Cells.
Kim C; Kim JH; Oh EY; Nam D; Lee SG; Lee J; Kim SH; Shim BS; Ahn KS
Pancreas; 2016 Mar; 45(3):409-19. PubMed ID: 26646273
[TBL] [Abstract] [Full Text] [Related]
20. Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic pancreatic cancer for Whom Therapy With Gemcitabine Has Failed.
Hurwitz HI; Uppal N; Wagner SA; Bendell JC; Beck JT; Wade SM; Nemunaitis JJ; Stella PJ; Pipas JM; Wainberg ZA; Manges R; Garrett WM; Hunter DS; Clark J; Leopold L; Sandor V; Levy RS
J Clin Oncol; 2015 Dec; 33(34):4039-47. PubMed ID: 26351344
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