Terms: = Pancreatic cancer AND KLK2, P20151, 3817, ENSG00000167751, MGC12201, hK2, KLK2A2
36 results:
1. AMPK-HIF-1α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth.
Yun HJ; Li M; Guo D; Jeon SM; Park SH; Lim JS; Lee SB; Liu R; Du L; Kim SH; Shin TH; Eyun SI; Park YY; Lu Z; Lee JH
J Exp Clin Cancer Res; 2023 Dec; 42(1):340. PubMed ID: 38098117
[TBL] [Abstract] [Full Text] [Related]
2. Glycolytic enzyme hk2 promotes PD-L1 expression and breast cancer cell immune evasion.
Lin J; Fang W; Xiang Z; Wang Q; Cheng H; Chen S; Fang J; Liu J; Wang Q; Lu Z; Ma L
Front Immunol; 2023; 14():1189953. PubMed ID: 37377974
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3. LINC00365 functions as a tumor suppressor by inhibiting HIF-1α-mediated glucose metabolism reprogramming in breast cancer.
Liu B; Qu X; Wang J; Xu L; Zhang L; Xu B; Su J; Bian X
Exp Cell Res; 2023 Apr; 425(1):113514. PubMed ID: 36804531
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4. UBR7 inhibits HCC tumorigenesis by targeting Keap1/Nrf2/Bach1/hk2 and glycolysis.
Zhao L; Kang M; Liu X; Wang Z; Wang Y; Chen H; Liu W; Liu S; Li B; Li C; Chang A; Tang B
J Exp Clin Cancer Res; 2022 Nov; 41(1):330. PubMed ID: 36419136
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5. Tumor-suppressive miR-323a inhibits pancreatic cancer cell proliferation and glycolysis through targeting HK-2.
Wei Y; Wang M; Liang M; Liu L; Mo S; Zhang H; Chen Y; Li N
Pathol Int; 2022 Dec; 72(12):617-630. PubMed ID: 36416387
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6. Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα.
Guo D; Tong Y; Jiang X; Meng Y; Jiang H; Du L; Wu Q; Li S; Luo S; Li M; Xiao L; He H; He X; Yu Q; Fang J; Lu Z
Cell Metab; 2022 Sep; 34(9):1312-1324.e6. PubMed ID: 36007522
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7. A non-metabolic function of hexokinase 2 in small cell lung cancer: promotes cancer cell stemness by increasing USP11-mediated CD133 stability.
Wang J; Shao F; Yang Y; Wang W; Yang X; Li R; Cheng H; Sun S; Feng X; Gao Y; He J; Lu Z
Cancer Commun (Lond); 2022 Oct; 42(10):1008-1027. PubMed ID: 35975322
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8. Hyperglycemia Enhances Immunosuppression and Aerobic Glycolysis of pancreatic cancer Through Upregulating Bmi1-UPF1-hk2 Pathway.
Wu S; Zhang H; Gao C; Chen J; Li H; Meng Z; Bai J; Shen Q; Wu H; Yin T
Cell Mol Gastroenterol Hepatol; 2022; 14(5):1146-1165. PubMed ID: 35863742
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9. A reciprocal feedback between N6-methyladenosine reader YTHDF3 and lncRNA DICER1-AS1 promotes glycolysis of pancreatic cancer through inhibiting maturation of miR-5586-5p.
Hu Y; Tang J; Xu F; Chen J; Zeng Z; Han S; Wang F; Wang D; Huang M; Zhao Y; Huang Y; Zhuo W; Zhao G
J Exp Clin Cancer Res; 2022 Feb; 41(1):69. PubMed ID: 35183226
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10. Development of a KRAS-Associated Metabolic Risk Model for Prognostic Prediction in pancreatic cancer.
Ma Z; Li Z; Ma Z; Zhou Z; Zhuang H; Liu C; Huang B; Zou Y; Zheng Z; Yang L; Gong Y; Huang S; Zhou Q; Zhang C; Hou B
Biomed Res Int; 2021; 2021():9949272. PubMed ID: 34660806
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11. Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities.
Meng YM; Jiang X; Zhao X; Meng Q; Wu S; Chen Y; Kong X; Qiu X; Su L; Huang C; Wang M; Liu C; Wong PP
Nat Commun; 2021 Oct; 12(1):6011. PubMed ID: 34650057
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12. Mechanistic Actions between
Nik Mohamed Kamal NNS; Abdul Aziz FA; Tan WN; Fauzi AN; Lim V
Molecules; 2021 Jun; 26(12):. PubMed ID: 34207699
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13. MIR210HG regulates glycolysis, cell proliferation, and metastasis of pancreatic cancer cells through miR-125b-5p/hk2/PKM2 axis.
Yu T; Li G; Wang C; Gong G; Wang L; Li C; Chen Y; Wang X
RNA Biol; 2021 Dec; 18(12):2513-2530. PubMed ID: 34110962
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14. Long non-coding RNA MSC-AS1 facilitates the proliferation and glycolysis of gastric cancer cells by regulating PFKFB3 expression.
Jin X; Qiao L; Fan H; Liao C; Zheng J; Wang W; Ma X; Yang M; Sun X; Zhao W
Int J Med Sci; 2021; 18(2):546-554. PubMed ID: 33390824
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15. Positive feedback in Cav-1-ROS signalling in PSCs mediates metabolic coupling between PSCs and tumour cells.
Shao S; Qin T; Qian W; Yue Y; Xiao Y; Li X; Zhang D; Wang Z; Ma Q; Lei J
J Cell Mol Med; 2020 Aug; 24(16):9397-9408. PubMed ID: 32633891
[TBL] [Abstract] [Full Text] [Related]
16. LncRNA HOTAIR knockdown inhibits glycolysis by regulating miR-130a-3p/HIF1A in hepatocellular carcinoma under hypoxia.
Hu M; Fu Q; Jing C; Zhang X; Qin T; Pan Y
Biomed Pharmacother; 2020 May; 125():109703. PubMed ID: 32062551
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17. Ikarugamycin inhibits pancreatic cancer cell glycolysis by targeting hexokinase 2.
Jiang SH; Dong FY; Da LT; Yang XM; Wang XX; Weng JY; Feng L; Zhu LL; Zhang YL; Zhang ZG; Sun YW; Li J; Xu MJ
FASEB J; 2020 Mar; 34(3):3943-3955. PubMed ID: 31944405
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18. TWIST1 transcriptionally regulates glycolytic genes to promote the Warburg metabolism in pancreatic cancer.
Wang XX; Yin GQ; Zhang ZH; Rong ZH; Wang ZY; Du DD; Wang YD; Gao RX; Xian GZ
Exp Cell Res; 2020 Jan; 386(1):111713. PubMed ID: 31705846
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19. Hexokinase 2 dimerization and interaction with voltage-dependent anion channel promoted resistance to cell apoptosis induced by gemcitabine in pancreatic cancer.
Fan K; Fan Z; Cheng H; Huang Q; Yang C; Jin K; Luo G; Yu X; Liu C
Cancer Med; 2019 Oct; 8(13):5903-5915. PubMed ID: 31426130
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20. Drp1 Promotes KRas-Driven Metabolic Changes to Drive pancreatic Tumor Growth.
Nagdas S; Kashatus JA; Nascimento A; Hussain SS; Trainor RE; Pollock SR; Adair SJ; Michaels AD; Sesaki H; Stelow EB; Bauer TW; Kashatus DF
Cell Rep; 2019 Aug; 28(7):1845-1859.e5. PubMed ID: 31412251
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