BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND KMT2A, TRX1, 4297, MLL, ENSG00000118058, MLL/GAS7, HTRX1, HRX, ALL-1, MLL1A, CXXC7
35 results:

  • 1. kmt2a associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics.
    Mouti MA; Deng S; Pook M; Malzahn J; Rendek A; Militi S; Nibhani R; Soonawalla Z; Oppermann U; Hwang CI; Pauklin S
    Nat Commun; 2023 Sep; 14(1):5685. PubMed ID: 37709746
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Clinically Defined Mutations in
    Duan S; Sheriff S; Elvis-Offiah UB; Witten BL; Sawyer TW; Sundaresan S; Cierpicki T; Grembecka J; Merchant JL
    Cancer Res Commun; 2023 Jul; 3(7):1318-1334. PubMed ID: 37492626
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. PI3K/ c-Myc/AFF4 axis promotes pancreatic tumorigenesis through fueling nucleotide metabolism.
    Ni C; Liu W; Zheng K; Guo S; Song B; Jing W; Li G; Li B; Ni C; Shi K; Jin G; Yu G
    Int J Biol Sci; 2023; 19(6):1968-1982. PubMed ID: 37063434
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Gene fusions are frequent in ACTH-secreting neuroendocrine neoplasms of the pancreas, but not in their non-pancreatic counterparts.
    Agaimy A; Kasajima A; Stoehr R; Haller F; Schubart C; Tögel L; Pfarr N; von Werder A; Pavel ME; Sessa F; Uccella S; La Rosa S; Klöppel G
    Virchows Arch; 2023 Mar; 482(3):507-516. PubMed ID: 36690805
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Integrative genomic and transcriptomic profiling reveals distinct molecular subsets in adult mixed phenotype acute leukemia.
    Wang Q; Cai WZ; Wang QR; Zhu MQ; Yan LZ; Yu Y; Bao XB; Shen HJ; Yao H; Xie JD; Zhang TT; Zhang L; Xu XY; Shan Z; Liu H; Cen JN; Liu DD; Pan JL; Lu DR; Chen J; Xu Y; Zhang R; Wang Y; Xue SL; Miao M; Han Y; Tang XW; Qiu HY; Sun AN; Huang JY; Dai HP; Wu DP; Chen SN
    Am J Hematol; 2023 Jan; 98(1):66-78. PubMed ID: 36219502
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Multi-omics analyses of MEN1 missense mutations identify disruption of menin-mll and menin-JunD interactions as critical requirements for molecular pathogenicity.
    Dreijerink KMA; Ozyerli-Goknar E; Koidl S; van der Lelij EJ; van den Heuvel P; Kooijman JJ; Biniossek ML; Rodenburg KW; Nizamuddin S; Timmers HTM
    Epigenetics Chromatin; 2022 Aug; 15(1):29. PubMed ID: 35941657
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Molecular deciphering of primary liver neuroendocrine neoplasms confirms their distinct existence with foregut-like profile.
    de Mestier L; Nicolle R; Poté N; Rebours V; Cauchy F; Hentic O; Maire F; Ronot M; Lebtahi R; Sauvanet A; Paradis V; Ruszniewski P; Couvelard A; Cros J
    J Pathol; 2022 Sep; 258(1):58-68. PubMed ID: 35681273
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Variation in Radiologists' Follow-Up Imaging Recommendations for Small Cystic pancreatic Lesions.
    Kapoor N; Lacson R; Eskian M; Cochon L; Glazer D; Ip I; Khorasani R
    J Am Coll Radiol; 2021 Oct; 18(10):1405-1414. PubMed ID: 34174205
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Risk stratification and prognostic factors in patients with unresectable undifferentiated carcinoma of the pancreas.
    Imaoka H; Ikeda M; Maehara K; Umemoto K; Ozaka M; Kobayashi S; Terashima T; Inoue H; Sakaguchi C; Tsuji K; Shioji K; Okamura K; Tsujimoto A; Nakamura I; Shirakawa H; Furukawa M; Ueno M; Morizane C; Furuse J
    Pancreatology; 2021 Jun; 21(4):738-745. PubMed ID: 33602645
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human pancreatic cancer Cells.
    Zhang W; Zhu Y; Yu H; Liu X; Jiao B; Lu X
    Molecules; 2021 Jan; 26(2):. PubMed ID: 33435380
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Menin‑mll inhibitors induce ferroptosis and enhance the anti‑proliferative activity of auranofin in several types of cancer cells.
    Kato I; Kasukabe T; Kumakura S
    Int J Oncol; 2020 Oct; 57(4):1057-1071. PubMed ID: 32945449
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Roles of GTP and Rho GTPases in pancreatic islet beta cell function and dysfunction.
    Kowluru A
    Small GTPases; 2021; 12(5-6):323-335. PubMed ID: 32867592
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Upregulation of DPY30 promotes cell proliferation and predicts a poor prognosis in cholangiocarcinoma.
    Hong ZF; Zhang WQ; Wang SJ; Li SY; Shang J; Liu F; Shen DY
    Biomed Pharmacother; 2020 Mar; 123():109766. PubMed ID: 31846841
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Disclosing progress in cancer survival with less delay.
    Jansen L; Schröder CC; Emrich K; Holleczek B; Pritzkuleit R; Brenner H
    Int J Cancer; 2020 Aug; 147(3):838-846. PubMed ID: 31785152
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Synergistic and Pharmacotherapeutic Effects of Gemcitabine and Cisplatin Combined Administration on Biliary Tract cancer Cell Lines.
    Sakamoto Y; Yamagishi S; Okusaka T; Ojima H
    Cells; 2019 Sep; 8(9):. PubMed ID: 31484399
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
    Chang S; Yim S; Park H
    Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Comprehensive cancer Panel Sequencing Defines Genetic Diversity and Changes in the Mutational Characteristics of pancreatic cancer Patients Receiving Neoadjuvant Treatment.
    Yoon KA; Woo SM; Kim YH; Kong SY; Lee MK; Han SS; Kim TH; Lee WJ; Park SJ
    Gut Liver; 2019 Nov; 13(6):683-689. PubMed ID: 30970447
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy.
    Lou M; Liu Q; Ren G; Zeng J; Xiang X; Ding Y; Lin Q; Zhong T; Liu X; Zhu L; Qi H; Shen J; Li H; Shao J
    J Biol Chem; 2017 Jun; 292(22):9136-9149. PubMed ID: 28411237
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours.
    Childs A; Vesely C; Ensell L; Lowe H; Luong TV; Caplin ME; Toumpanakis C; Thirlwell C; Hartley JA; Meyer T
    Br J Cancer; 2016 Dec; 115(12):1540-1547. PubMed ID: 27875519
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The American Society of Peritoneal Surface Malignancies Multi-Institution evaluation of 1,051 advanced ovarian cancer patients undergoing cytoreductive surgery and HIPEC: An introduction of the peritoneal surface disease severity score.
    Foster JM; Sleightholm R; Smith L; Ceelen W; Deraco M; Yildirim Y; Levine E; Muñoz-Casares C; Glehen O; Patel A; Esquivel J
    J Surg Oncol; 2016 Dec; 114(7):779-784. PubMed ID: 27792292
    [TBL] [Abstract] [Full Text] [Related]  


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