Terms: = Pancreatic cancer AND MYCN, N-myc, 4613, ENSG00000134323, NMYC, MODED, ODED AND Treatment
21 results:
1. Integrative analysis of disulfidptosis and immune microenvironment in hepatocellular carcinoma: a putative model and immunotherapeutic strategies.
Yang T; Liu J; Liu F; Lei J; Chen S; Ma Z; Ke P; Yang Q; Wen J; He Y; Duan J; Zeng X
Front Immunol; 2023; 14():1294677. PubMed ID: 38235128
[TBL] [Abstract] [Full Text] [Related]
2. NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
Zhang Z; Song B; Wei H; Liu Y; Zhang W; Yang Y; Sun B
Drug Resist Updat; 2024 Mar; 73():101040. PubMed ID: 38228036
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3. Repurposing a plant alkaloid homoharringtonine targets insulinoma associated-1 in n-myc-activated neuroblastoma.
Chen C; Wu J; Hicks C; Lan MS
Cell Signal; 2023 Sep; 109():110753. PubMed ID: 37301315
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4. Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma.
Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z
FASEB J; 2021 Feb; 35(2):e21347. PubMed ID: 33484481
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5. NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization.
Sahni S; Gillson J; Park KC; Chiang S; Leck LYW; Jansson PJ; Richardson DR
Biochim Biophys Acta Gen Subj; 2020 Aug; 1864(8):129625. PubMed ID: 32335136
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6. NELFE promoted pancreatic cancer metastasis and the epithelial‑to‑mesenchymal transition by decreasing the stabilization of NDRG2 mRNA.
Han L; Zan Y; Huang C; Zhang S
Int J Oncol; 2019 Dec; 55(6):1313-1323. PubMed ID: 31638184
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7. Investigating the Contribution of Collagen to the Tumor Biomechanical Phenotype with Noninvasive Magnetic Resonance Elastography.
Li J; Zormpas-Petridis K; Boult JKR; Reeves EL; Heindl A; Vinci M; Lopes F; Cummings C; Springer CJ; Chesler L; Jones C; Bamber JC; Yuan Y; Sinkus R; Jamin Y; Robinson SP
Cancer Res; 2019 Nov; 79(22):5874-5883. PubMed ID: 31604713
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8. Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer.
Emmanouilidi A; Fyffe CA; Ferro R; Edling CE; Capone E; Sestito S; Rapposelli S; Lattanzio R; Iacobelli S; Sala G; Maffucci T; Falasca M
J Exp Clin Cancer Res; 2019 May; 38(1):191. PubMed ID: 31088502
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9. Role of metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) in pancreatic cancer.
Cheng Y; Imanirad P; Jutooru I; Hedrick E; Jin UH; Rodrigues Hoffman A; Leal de Araujo J; Morpurgo B; Golovko A; Safe S
PLoS One; 2018; 13(2):e0192264. PubMed ID: 29389953
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10. Histone Deacetylase Inhibition Restores Expression of Hypoxia-Inducible Protein NDRG1 in pancreatic cancer.
Tiffon C
Pancreas; 2018 Feb; 47(2):200-207. PubMed ID: 29303911
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11. Molecular characterization of metastatic pancreatic neuroendocrine tumors (PNETs) using whole-genome and transcriptome sequencing.
Wong HL; Yang KC; Shen Y; Zhao EY; Loree JM; Kennecke HF; Kalloger SE; Karasinska JM; Lim HJ; Mungall AJ; Feng X; Davies JM; Schrader K; Zhou C; Karsan A; Jones SJM; Laskin J; Marra MA; Schaeffer DF; Gorski SM; Renouf DJ
Cold Spring Harb Mol Case Stud; 2018 Feb; 4(1):. PubMed ID: 29092957
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12. NDRG2, suppressed expression associates with poor prognosis in pancreatic cancer, is hypermethylated in the second promoter in human gastrointestinal cancers.
Yamamura A; Miura K; Karasawa H; Motoi F; Mizuguchi Y; Saiki Y; Fukushige S; Sunamura M; Shibata C; Unno M; Horii A
Biochem Biophys Res Commun; 2017 Feb; 484(1):138-143. PubMed ID: 28093228
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13. Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing mycn in hGFAP-positive cells.
Fielitz K; Althoff K; De Preter K; Nonnekens J; Ohli J; Elges S; Hartmann W; Klöppel G; Knösel T; Schulte M; Klein-Hitpass L; Beisser D; Reis H; Eyking A; Cario E; Schulte JH; Schramm A; Schüller U
Oncotarget; 2016 Nov; 7(46):74415-74426. PubMed ID: 27769070
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14. The Metastasis Suppressor, n-myc Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
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15. Molecular foundations for personalized therapy in prostate cancer.
Fisher KW; Montironi R; Lopez Beltran A; Moch H; Wang L; Scarpelli M; Williamson SR; Koch MO; Cheng L
Curr Drug Targets; 2015; 16(2):103-14. PubMed ID: 25547910
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16. The silencing of n-myc downstream-regulated gene-1 in an orthotopic pancreatic cancer model leads to more aggressive tumor growth and metastases.
Kim-Fuchs C; Winterhalder S; Winter A; Malinka T; Born D; Schäfer S; Stroka D; Gloor B; Candinas D; Angst E
Dig Surg; 2014; 31(2):135-42. PubMed ID: 24970329
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17. Suppressed expression of NDRG2 correlates with poor prognosis in pancreatic cancer.
Yamamura A; Miura K; Karasawa H; Morishita K; Abe K; Mizuguchi Y; Saiki Y; Fukushige S; Kaneko N; Sase T; Nagase H; Sunamura M; Motoi F; Egawa S; Shibata C; Unno M; Sasaki I; Horii A
Biochem Biophys Res Commun; 2013 Nov; 441(1):102-7. PubMed ID: 24134849
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18. Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor n-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer.
Kovacevic Z; Chikhani S; Lovejoy DB; Richardson DR
Mol Pharmacol; 2011 Oct; 80(4):598-609. PubMed ID: 21719465
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19. Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects.
Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair T; Scarlett CJ; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Keating J; Sekyere E; Jonquieres G; Stossi F; Katzenellenbogen BS; Biankin AV; Perini G; Liu T
Oncogene; 2010 Nov; 29(44):5957-68. PubMed ID: 20697349
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20. Epigenetic regulation affects n-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells.
Angst E; Dawson DW; Nguyen A; Park J; Go VL; Reber HA; Hines OJ; Eibl G
Pancreas; 2010 Jul; 39(5):675-9. PubMed ID: 20173668
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