BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND NOTCH1, TAN1, P46531, 4851, ENSG00000148400, hN1 AND Treatment
50 results:

  • 1. Lycorine inhibits pancreatic cancer cell growth and neovascularization by inducing notch1 degradation and downregulating key vasculogenic genes.
    Qi J; Meng M; Liu J; Song X; Chen Y; Liu Y; Li X; Zhou Z; Huang X; Wang X; Zhou Q; Zhao Z
    Biochem Pharmacol; 2023 Nov; 217():115833. PubMed ID: 37769714
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Umbelliprenin induces autophagy and apoptosis while inhibits cancer cell stemness in pancreatic cancer cells.
    Wang H; Liu Y; Wang Y; Xu T; Xia G; Huang X
    Cancer Med; 2023 Jul; 12(14):15277-15288. PubMed ID: 37409635
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. The effect of GP-2250 on cultured virus-negative Merkel cell carcinoma cells: preliminary results.
    Gambichler T; Majchrzak-Stiller B; Peters I; Becker JC; Strotmann J; Abu Rached N; Müller T; Uhl W; Buchholz M; Braumann C
    J Cancer Res Clin Oncol; 2023 Sep; 149(12):10831-10840. PubMed ID: 37311987
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Simultaneous activation of Kras-Akt and Notch pathways induces extrahepatic biliary cancer via the mTORC1 pathway.
    Namikawa M; Fukuda A; Mizukoshi K; Iwane K; Kawai M; Yamakawa G; Omatsu M; Sono M; Masuda T; Araki O; Nagao M; Yoshikawa T; Ogawa S; Hiramatsu Y; Muta Y; Tsuda M; Maruno T; Nakanishi Y; Tsuruyama T; Taura K; Hatano E; Seno H
    J Pathol; 2023 Aug; 260(4):478-492. PubMed ID: 37310065
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Splicing factor SNRPA associated with microvascular invasion promotes hepatocellular carcinoma metastasis through activating notch1/Snail pathway and is mediated by circSEC62/miR-625-5p axis.
    Mo Z; Li R; Cao C; Li Y; Zheng S; Wu R; Xue J; Hu J; Meng H; Zhai H; Huang W; Zheng F; Zhou B
    Environ Toxicol; 2023 May; 38(5):1022-1037. PubMed ID: 36715182
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. RHBDL2 promotes the proliferation, migration, and invasion of pancreatic cancer by stabilizing the N1ICD via the OTUD7B and activating the Notch signaling pathway.
    Chen S; Cai K; Zheng D; Liu Y; Li L; He Z; Sun C; Yu C
    Cell Death Dis; 2022 Nov; 13(11):945. PubMed ID: 36351890
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Deubiquitinase UCHL5 stabilizes ELK3 to potentiate cancer stemness and tumor progression in pancreatic adenocarcinoma (PAAD).
    Yang Y; Cao L; Guo Z; Gu H; Zhang K; Qiu Z
    Exp Cell Res; 2022 Dec; 421(2):113402. PubMed ID: 36328194
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Integrative genomic and transcriptomic profiling reveals distinct molecular subsets in adult mixed phenotype acute leukemia.
    Wang Q; Cai WZ; Wang QR; Zhu MQ; Yan LZ; Yu Y; Bao XB; Shen HJ; Yao H; Xie JD; Zhang TT; Zhang L; Xu XY; Shan Z; Liu H; Cen JN; Liu DD; Pan JL; Lu DR; Chen J; Xu Y; Zhang R; Wang Y; Xue SL; Miao M; Han Y; Tang XW; Qiu HY; Sun AN; Huang JY; Dai HP; Wu DP; Chen SN
    Am J Hematol; 2023 Jan; 98(1):66-78. PubMed ID: 36219502
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. The multifaceted mechanisms of Paeoniflorin in the treatment of tumors: State-of-the-Art.
    Wang XZ; Xia L; Zhang XY; Chen Q; Li X; Mou Y; Wang T; Zhang YN
    Biomed Pharmacother; 2022 May; 149():112800. PubMed ID: 35279012
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Activation of the notch1-c-myc-VCAM1 signalling axis initiates liver progenitor cell-driven hepatocarcinogenesis and pulmonary metastasis.
    Wu WR; Shi XD; Zhang FP; Zhu K; Zhang R; Yu XH; Qin YF; He SP; Fu HW; Zhang L; Zeng H; Zhu MS; Xu LB; Wong PP; Liu C
    Oncogene; 2022 Apr; 41(16):2340-2356. PubMed ID: 35256782
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. MUC1-C dictates neuroendocrine lineage specification in pancreatic ductal adenocarcinomas.
    Luan Z; Morimoto Y; Fushimi A; Yamashita N; Suo W; Bhattacharya A; Hagiwara M; Jin C; Kufe D
    Carcinogenesis; 2022 Feb; 43(1):67-76. PubMed ID: 34657147
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. CDK5 positively regulates notch1 signaling in pancreatic cancer cells by phosphorylation.
    Chu Q; Wang L; Zhang J; Wang W; Wang Y
    Cancer Med; 2021 Jun; 10(11):3689-3699. PubMed ID: 33960694
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Association of Jagged1 expression with malignancy and prognosis in human pancreatic cancer.
    Lee J; Lee J; Kim JH
    Cell Oncol (Dordr); 2020 Oct; 43(5):821-834. PubMed ID: 32483746
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Long non-coding RNA MACC1-AS1 promoted pancreatic carcinoma progression through activation of PAX8/notch1 signaling pathway.
    Qi C; Xiaofeng C; Dongen L; Liang Y; Liping X; Yue H; Jianshuai J
    J Exp Clin Cancer Res; 2019 Aug; 38(1):344. PubMed ID: 31391063
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Hypoxia potentiates gemcitabine-induced stemness in pancreatic cancer cells through AKT/notch1 signaling.
    Zhang Z; Han H; Rong Y; Zhu K; Zhu Z; Tang Z; Xiong C; Tao J
    J Exp Clin Cancer Res; 2018 Nov; 37(1):291. PubMed ID: 30486896
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Norepinephrine enhances cell viability and invasion, and inhibits apoptosis of pancreatic cancer cells in a Notch‑1‑dependent manner.
    Qian W; Lv S; Li J; Chen K; Jiang Z; Cheng L; Zhou C; Yan B; Cao J; Ma Q; Duan W
    Oncol Rep; 2018 Nov; 40(5):3015-3023. PubMed ID: 30226612
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Notch signaling molecule is involved in the invasion of MiaPaCa2 cells induced by CoCl2 via regulating epithelial‑mesenchymal transition.
    Chen DW; Wang H; Bao YF; Xie K
    Mol Med Rep; 2018 Apr; 17(4):4965-4972. PubMed ID: 29393429
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Leptin-Notch signaling axis is involved in pancreatic cancer progression.
    Harbuzariu A; Rampoldi A; Daley-Brown DS; Candelaria P; Harmon TL; Lipsey CC; Beech DJ; Quarshie A; Ilies GO; Gonzalez-Perez RR
    Oncotarget; 2017 Jan; 8(5):7740-7752. PubMed ID: 27999190
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Antitumor activity of curcumin is involved in down-regulation of YAP/TAZ expression in pancreatic cancer cells.
    Zhou X; Su J; Feng S; Wang L; Yin X; Yan J; Wang Z
    Oncotarget; 2016 Nov; 7(48):79076-79088. PubMed ID: 27738325
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. A Phase II Trial of a Histone Deacetylase Inhibitor Panobinostat in Patients With Low-Grade Neuroendocrine Tumors.
    Jin N; Lubner SJ; Mulkerin DL; Rajguru S; Carmichael L; Chen H; Holen KD; LoConte NK
    Oncologist; 2016 Jul; 21(7):785-6. PubMed ID: 27261467
    [TBL] [Abstract] [Full Text] [Related]  


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