Terms: = Pancreatic cancer AND PRKAR1A, DKFZp779L0468, 5573, ENSG00000108946, PRKAR1, P10644, CNC1, PKR1, MGC17251, PPNAD1, TSE1, CNC, CAR AND Treatment
124 results:
1. Armored TGFβRIIDN ROR1-car T cells reject solid tumors and resist suppression by constitutively-expressed and treatment-induced TGFβ1.
Tran TM; Chand Thakuri BK; Nurmukhambetova S; Lee JJ; Hu P; Tran NQ; Steimle B; Dash P; Schneider D
J Immunother Cancer; 2024 Apr; 12(4):. PubMed ID: 38609317
[TBL] [Abstract] [Full Text] [Related]
2. Complete remission of advanced pancreatic cancer induced by claudin18.2-targeted car-T cell therapy: a case report.
Zhong G; Zhang X; Guo Z; Gao Y; Zhao B; Liu X; Chen L; Qiao J; Yu C; Wang L; Li Y; Yu L
Front Immunol; 2024; 15():1325860. PubMed ID: 38487523
[TBL] [Abstract] [Full Text] [Related]
3. IL-15-secreting car natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts.
Van den Eynde A; Gehrcken L; Verhezen T; Lau HW; Hermans C; Lambrechts H; Flieswasser T; Quatannens D; Roex G; Zwaenepoel K; Marcq E; Joye P; Cardenas De La Hoz E; Deben C; Gasparini A; Montay-Gruel P; Le Compte M; Lion E; Lardon F; Van Laere S; Siozopoulou V; Campillo-Davo D; De Waele J; Pauwels P; Jacobs J; Smits E; Van Audenaerde JRM
J Hematol Oncol; 2024 Feb; 17(1):8. PubMed ID: 38331849
[TBL] [Abstract] [Full Text] [Related]
4. The role of microbial metabolites in endocrine tumorigenesis: From the mechanistic insights to potential therapeutic biomarkers.
Zhang Y; Tang N; Zhou H; Zhu Y
Biomed Pharmacother; 2024 Mar; 172():116218. PubMed ID: 38308969
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5. New CEACAM-targeting 2A3 single-domain antibody-based chimeric antigen receptor T-cells produce anticancer effects in vitro and in vivo.
Jancewicz I; Śmiech M; Winiarska M; Zagozdzon R; Wisniewski P
Cancer Immunol Immunother; 2024 Jan; 73(2):30. PubMed ID: 38279989
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6. Mucin-1-Targeted Chimeric Antigen Receptor T Cells Are Effective and Safe in Controlling Solid Tumors in Immunocompetent Host.
Zhou R; Wu ST; Yazdanifar M; Williams C; Sanders A; Brouwer C; Maher J; Mukherjee P
J Immunother; 2024 Apr; 47(3):77-88. PubMed ID: 38270462
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7. Using Oncolytic Virus to Retask CD19-Chimeric Antigen Receptor T Cells for treatment of pancreatic cancer: Toward a Universal Chimeric Antigen Receptor T-Cell Strategy for Solid Tumor.
Chen C; Park AK; Monroy I; Ren Y; Kim SI; Chaurasiya S; Priceman SJ; Fong Y
J Am Coll Surg; 2024 Apr; 238(4):436-447. PubMed ID: 38214445
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8. Chimeric Antigen Receptor T Cell Therapy for pancreatic cancer: A Review of Current Evidence.
Czaplicka A; Lachota M; Pączek L; Zagożdżon R; Kaleta B
Cells; 2024 Jan; 13(1):. PubMed ID: 38201305
[TBL] [Abstract] [Full Text] [Related]
9. Exhaustion, rather than lack of infiltration and persistence, of car-T cells hampers the efficacy of car-T therapy in an orthotopic PDAC xenograft model.
Takeuchi Y; Wang Y; Sasaki K; Sato O; Tsuchikawa T; Wang L; Amaishi Y; Okamoto S; Mineno J; Hirokawa Y; Hatanaka KC; Hatanaka Y; Kato T; Shiku H; Hirano S
Biomed Pharmacother; 2024 Jan; 170():116052. PubMed ID: 38141280
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10. Systemic inflammation adversely affects response to anamorelin in patients with pancreatic cancer.
Tsunematsu M; Uwagawa T; Onda S; Shirai Y; Okui N; Matsumoto M; Furukawa K; Haruki K; Ishizaki S; Ikegami T
Support Care Cancer; 2023 Nov; 31(12):732. PubMed ID: 38055066
[TBL] [Abstract] [Full Text] [Related]
11. Natural killer cells for pancreatic cancer immunotherapy: Role of nanoparticles.
Kumar V; Mahato RI
Cancer Lett; 2023 Nov; 579():216462. PubMed ID: 37924937
[TBL] [Abstract] [Full Text] [Related]
12. Arming car-T cells with cytokines and more: Innovations in the fourth-generation car-T development.
Tang L; Pan S; Wei X; Xu X; Wei Q
Mol Ther; 2023 Nov; 31(11):3146-3162. PubMed ID: 37803832
[TBL] [Abstract] [Full Text] [Related]
13. "Hurdles race for car T-cell therapy in digestive tract cancer".
Kronig MN; Wehrli M; Salas-Benito D; Maus MV
Immunol Rev; 2023 Nov; 320(1):100-119. PubMed ID: 37694970
[TBL] [Abstract] [Full Text] [Related]
14. Effect of chimeric antigen receptor T cells against protease-activated receptor 1 for treating pancreatic cancer.
Hung HC; Fan MH; Wang D; Miao CH; Su P; Liu CL
BMC Med; 2023 Sep; 21(1):338. PubMed ID: 37667257
[TBL] [Abstract] [Full Text] [Related]
15. Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors.
Xiao Z; Todd L; Huang L; Noguera-Ortega E; Lu Z; Huang L; Kopp M; Li Y; Pattada N; Zhong W; Guo W; Scholler J; Liousia M; Assenmacher CA; June CH; Albelda SM; Puré E
Nat Commun; 2023 Aug; 14(1):5110. PubMed ID: 37607999
[TBL] [Abstract] [Full Text] [Related]
16. Preconditioning of radiotherapy enhances efficacy of B7-H3-car-T in treating solid tumor models.
Wang T; Zhang K; You F; Ma R; Yang N; Tian S; An G; Yang L
Life Sci; 2023 Oct; 331():122024. PubMed ID: 37574043
[TBL] [Abstract] [Full Text] [Related]
17. PGE2-EP2/EP4 signaling elicits mesocar T cell immunosuppression in pancreatic cancer.
Akbari B; Soltantoyeh T; Shahosseini Z; Jadidi-Niaragh F; Hadjati J; Brown CE; Mirzaei HR
Front Immunol; 2023; 14():1209572. PubMed ID: 37457723
[TBL] [Abstract] [Full Text] [Related]
18. Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8
Li P; Zhou D; Chen D; Cheng Y; Chen Y; Lin Z; Zhang X; Huang Z; Cai J; Huang W; Lin Y; Ke H; Long J; Zou Y; Ye S; Lan P
J Biomed Sci; 2023 Jun; 30(1):47. PubMed ID: 37380972
[TBL] [Abstract] [Full Text] [Related]
19. Radiation therapy improves car T cell activity in acute lymphoblastic leukemia.
Sugita M; Yamazaki T; Alhomoud M; Martinet J; Latouche JB; Golden E; Boyer O; Van Besien K; Formenti SC; Galluzzi L; Guzman ML
Cell Death Dis; 2023 May; 14(5):305. PubMed ID: 37142568
[TBL] [Abstract] [Full Text] [Related]
20. FAP-targeted car-T suppresses MDSCs recruitment to improve the antitumor efficacy of claudin18.2-targeted car-T against pancreatic cancer.
Liu Y; Sun Y; Wang P; Li S; Dong Y; Zhou M; Shi B; Jiang H; Sun R; Li Z
J Transl Med; 2023 Apr; 21(1):255. PubMed ID: 37046312
[TBL] [Abstract] [Full Text] [Related]
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