Terms: = Pancreatic cancer AND PTCH1, RP11-435O5_3, Q13635, PTCH, 5727, HPE7, FLJ26746, NBCCS, BCNS, PTC1, ENSG00000185920, FLJ42602
63 results:
1. 2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines.
Kotulova J; Lonova K; Kubickova A; Vrbkova J; Kourilova P; Hajduch M; Dzubak P
Int J Mol Med; 2022 Mar; 49(3):. PubMed ID: 35039871
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2. Characterization and Biological Evaluation of Solid Dispersed Nanoparticles of Synthetic Epoksilignan Targeting pancreatic cancer Cell as an Anticancer Agent.
Rifai Y; Tanggulungan W; Rahman L; Bhuyan DJ
J Biomed Nanotechnol; 2021 Jul; 17(7):1453-1458. PubMed ID: 34446148
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3. Prevalence and spectrum of pathogenic germline variants in intestinal and pancreatobiliary type of ampullary cancer.
Kumari N; Singh RK; Mishra SK; L R; Mohindra S; Krishnani N
Pathol Res Pract; 2021 Jan; 217():153309. PubMed ID: 33341547
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4. The Role of Smoothened in cancer.
Jeng KS; Sheen IS; Leu CM; Tseng PH; Chang CF
Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32962123
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5. GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
Tolosa EJ; Fernandez-Barrena MG; Iguchi E; McCleary-Wheeler AL; Carr RM; Almada LL; Flores LF; Vera RE; Alfonse GW; Marks DL; Hogenson TL; Vrabel AM; Horn IP; Koenig AN; Safgren SL; Sigafoos AN; Erkan M; Romecin-Duran PA; Sarabia Gonzalez A; Zhou B; Javelaud D; Marsaud V; Graham RP; Mauviel A; Elsawa SF; Fernandez-Zapico ME
Biochem J; 2020 Sep; 477(17):3131-3145. PubMed ID: 32766732
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6. Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis.
Bissey PA; Mathot P; Guix C; Jasmin M; Goddard I; Costechareyre C; Gadot N; Delcros JG; Mali SM; Fasan R; Arrigo AP; Dante R; Ichim G; Mehlen P; Fombonne J
Cancer Res; 2020 May; 80(10):1970-1980. PubMed ID: 32060146
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7. Should platinum-based chemotherapy be preferred for germline BReast cancer genes (BRCA) 1 and 2-mutated pancreatic ductal adenocarcinoma (PDAC) patients? A systematic review and meta-analysis.
Rebelatto TF; Falavigna M; Pozzari M; Spada F; Cella CA; Laffi A; Pellicori S; Fazio N
Cancer Treat Rev; 2019 Nov; 80():101895. PubMed ID: 31542591
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8. TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Zhu R; Gires O; Zhu L; Liu J; Li J; Yang H; Ju G; Huang J; Ge W; Chen Y; Lu Z; Wang H
Nat Commun; 2019 Jun; 10(1):2863. PubMed ID: 31253779
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9. Genomic testing, tumor microenvironment and targeted therapy of Hedgehog-related human cancers.
Katoh M
Clin Sci (Lond); 2019 Apr; 133(8):953-970. PubMed ID: 31036756
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10. Prevalence of Germline Mutations Associated With cancer Risk in Patients With Intraductal Papillary Mucinous Neoplasms.
Skaro M; Nanda N; Gauthier C; Felsenstein M; Jiang Z; Qiu M; Shindo K; Yu J; Hutchings D; Javed AA; Beckman R; He J; Wolfgang CL; Thompson E; Hruban RH; Klein AP; Goggins M; Wood LD; Roberts NJ
Gastroenterology; 2019 May; 156(6):1905-1913. PubMed ID: 30716324
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11. The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
Skoda AM; Simovic D; Karin V; Kardum V; Vranic S; Serman L
Bosn J Basic Med Sci; 2018 Feb; 18(1):8-20. PubMed ID: 29274272
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12. Sunitinib in the Treatment of Thyroid cancer.
Ferrari SM; Centanni M; Virili C; Miccoli M; Ferrari P; Ruffilli I; Ragusa F; Antonelli A; Fallahi P
Curr Med Chem; 2019; 26(6):963-972. PubMed ID: 28990511
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13. Efficient Synthesis of Heterocyclic Flavonoids with Hedgehog Signal Inhibitory Activity.
Arai MA; Utsumi T; Yanase N; Fujimatsu T; Ishibashi M
Chem Pharm Bull (Tokyo); 2017; 65(8):784-795. PubMed ID: 28768932
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14. Synthesis, Molecular Mechanism and Pharmacokinetic Studies of New Epoxy Lignan-Based Derivatives.
Rifai Y; Tani HB; Nur M; Aswad M; Lallo S; Wahyudin E
Arch Pharm (Weinheim); 2016 Nov; 349(11):848-852. PubMed ID: 27699826
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15. Dual role of the integrated stress response in medulloblastoma tumorigenesis.
Stone S; Ho Y; Li X; Jamison S; Harding HP; Ron D; Lin W
Oncotarget; 2016 Sep; 7(39):64124-64135. PubMed ID: 27802424
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16. Epithelial to Stromal Re-Distribution of Primary Cilia during pancreatic Carcinogenesis.
Schimmack S; Kneller S; Dadabaeva N; Bergmann F; Taylor A; Hackert T; Werner J; Strobel O
PLoS One; 2016; 11(10):e0164231. PubMed ID: 27783689
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17. Hedgehog pathway overexpression in pancreatic cancer is abrogated by new-generation taxoid SB-T-1216.
Mohelnikova-Duchonova B; Kocik M; Duchonova B; Brynychova V; Oliverius M; Hlavsa J; Honsova E; Mazanec J; Kala Z; Ojima I; Hughes DJ; Doherty JE; Murray HA; Crockard MA; Lemstrova R; Soucek P
Pharmacogenomics J; 2017 Oct; 17(5):452-460. PubMed ID: 27573236
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18. PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis.
Ho Y; Li X; Jamison S; Harding HP; McKinnon PJ; Ron D; Lin W
Am J Pathol; 2016 Jul; 186(7):1939-1951. PubMed ID: 27181404
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19. Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 To Treat pancreatic cancer.
Karaca M; Dutta R; Ozsoy Y; Mahato RI
Mol Pharm; 2016 Jun; 13(6):1822-32. PubMed ID: 26981724
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20. Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets.
Lee H; Wang K; Johnson A; Jones DM; Ali SM; Elvin JA; Yelensky R; Lipson D; Miller VA; Stephens PJ; Javle M; Ross JS
J Clin Pathol; 2016 May; 69(5):403-8. PubMed ID: 26500333
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