Terms: = Pancreatic cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25
93 results:
1. Vav1-dependent rac1 activation mediates hypoxia-induced gemcitabine resistance in pancreatic ductal adenocarcinoma cells through upregulation of HIF-1α expression.
Zhu C; Hu H; Ma Y; Xiong S; Zhu D
Cell Biol Int; 2023 Nov; 47(11):1835-1842. PubMed ID: 37545183
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2. Cytomorphologic, immunophenotypical and molecular features of pancreatic acinar cell carcinoma.
Sun T; Gilani S; Jain D; Cai G
Diagn Cytopathol; 2023 Nov; 51(11):674-683. PubMed ID: 37469257
[TBL] [Abstract] [Full Text] [Related]
3. MicroRNA-561-5p Inhibits Cell Proliferation and Invasion by Targeting rac1 in pancreatic Ductal Adenocarcinoma.
Xi B; Lai M; Zhang W; Wang F
Ann Clin Lab Sci; 2022 Mar; 52(2):213-221. PubMed ID: 35414500
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4. KRAS
Hobbs GA; Der CJ
Subcell Biochem; 2022; 98():205-221. PubMed ID: 35378710
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5. Mucin 5AC-Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate pancreatic cancer Stromal Heterogeneity.
Ganguly K; Cox JL; Ghersi D; Grandgenett PM; Hollingsworth MA; Jain M; Kumar S; Batra SK
Gastroenterology; 2022 Jun; 162(7):2032-2046.e12. PubMed ID: 35219699
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6. Disruption of FDPS/rac1 axis radiosensitizes pancreatic ductal adenocarcinoma by attenuating DNA damage response and immunosuppressive signalling.
Seshacharyulu P; Halder S; Nimmakayala R; Rachagani S; Chaudhary S; Atri P; Chirravuri-Venkata R; Ouellette MM; Carmicheal J; Gautam SK; Vengoji R; Wang S; Li S; Smith L; Talmon GA; Klute K; Ly Q; Reames BN; Grem JL; Berim L; Padussis JC; Kaur S; Kumar S; Ponnusamy MP; Jain M; Lin C; Batra SK
EBioMedicine; 2022 Jan; 75():103772. PubMed ID: 34971971
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7. rac1 Activation as a Potential Therapeutic Option in Metastatic Cutaneous Melanoma.
Colón-Bolea P; García-Gómez R; Casar B
Biomolecules; 2021 Oct; 11(11):. PubMed ID: 34827551
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8. Mechanical Stress Signaling in pancreatic cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via rac1/cdc42/Myosin II.
Kalli M; Li R; Mills GB; Stylianopoulos T; Zervantonakis IK
Mol Cancer Res; 2022 Mar; 20(3):485-497. PubMed ID: 34782370
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9. PD-1/PD-L1-Associated Immunoarchitectural Patterns Stratify pancreatic cancer Patients into Prognostic/Predictive Subgroups.
Karamitopoulou E; Andreou A; Pahud de Mortanges A; Tinguely M; Gloor B; Perren A
Cancer Immunol Res; 2021 Dec; 9(12):1439-1450. PubMed ID: 34526323
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10. Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.
Waters AM; Khatib TO; Papke B; Goodwin CM; Hobbs GA; Diehl JN; Yang R; Edwards AC; Walsh KH; Sulahian R; McFarland JM; Kapner KS; Gilbert TSK; Stalnecker CA; Javaid S; Barkovskaya A; Grover KR; Hibshman PS; Blake DR; Schaefer A; Nowak KM; Klomp JE; Hayes TK; Kassner M; Tang N; Tanaseichuk O; Chen K; Zhou Y; Kalkat M; Herring LE; Graves LM; Penn LZ; Yin HH; Aguirre AJ; Hahn WC; Cox AD; Der CJ
Cell Rep; 2021 Jun; 35(13):109291. PubMed ID: 34192548
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11. ARHGAP25 Inhibits pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway.
Huang WK; Chen Y; Su H; Chen TY; Gao J; Liu Y; Yeh CN; Li S
Int J Biol Sci; 2021; 17(7):1808-1820. PubMed ID: 33994864
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12. The Ratio of rac1B to rac1 Expression in Breast cancer Cell Lines as a Determinant of Epithelial/Mesenchymal Differentiation and Migratory Potential.
Eiden C; Ungefroren H
Cells; 2021 Feb; 10(2):. PubMed ID: 33567745
[TBL] [Abstract] [Full Text] [Related]
13. mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote Kras
Zhao Y; Schoeps B; Yao D; Zhang Z; Schuck K; Tissen V; Jäger C; Schlitter AM; van der Kammen R; Ludwig C; D'Haese JG; Raulefs S; Maeritz N; Shen S; Zou X; Krüger A; Kleeff J; Michalski CW; Friess H; Innocenti M; Kong B
Gastroenterology; 2021 Apr; 160(5):1755-1770.e17. PubMed ID: 33388318
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14. Elevated TIAM2 expression promotes tumor progression and is associated with unfavorable prognosis in pancreatic cancer.
Jiang B; Zhou L; Lu J; Wang Y; Liu C; Zhou W; Guo J
Scand J Gastroenterol; 2021 Jan; 56(1):59-67. PubMed ID: 33284659
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15. rac1 and EGFR cooperate to activate Pak in response to nutrient stress.
Lee SW; Commisso C
Biochem Biophys Res Commun; 2020 Dec; 533(3):437-441. PubMed ID: 32972756
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16. Roles of GTP and Rho GTPases in pancreatic islet beta cell function and dysfunction.
Kowluru A
Small GTPases; 2021; 12(5-6):323-335. PubMed ID: 32867592
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17. Evaluation of active rac1 levels in cancer cells: A case of misleading conclusions from immunofluorescence analysis.
Baker MJ; Cooke M; Kreider-Letterman G; Garcia-Mata R; Janmey PA; Kazanietz MG
J Biol Chem; 2020 Oct; 295(40):13698-13710. PubMed ID: 32817335
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18. Invasion inhibition in pancreatic cancer using the oral iron chelating agent deferasirox.
Amano S; Kaino S; Shinoda S; Harima H; Matsumoto T; Fujisawa K; Takami T; Yamamoto N; Yamasaki T; Sakaida I
BMC Cancer; 2020 Jul; 20(1):681. PubMed ID: 32698792
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19. Pattern of Invasion in Human pancreatic cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome.
Huang W; Navarro-Serer B; Jeong YJ; Chianchiano P; Xia L; Luchini C; Veronese N; Dowiak C; Ng T; Trujillo MA; Huang B; Pflüger MJ; Macgregor-Das AM; Lionheart G; Jones D; Fujikura K; Nguyen-Ngoc KV; Neumann NM; Groot VP; Hasanain A; van Oosten AF; Fischer SE; Gallinger S; Singhi AD; Zureikat AH; Brand RE; Gaida MM; Heinrich S; Burkhart RA; He J; Wolfgang CL; Goggins MG; Thompson ED; Roberts NJ; Ewald AJ; Wood LD
Cancer Res; 2020 Jul; 80(13):2804-2817. PubMed ID: 32376602
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20. Cdc42 Mediates cancer Cell Chemotaxis in Perineural Invasion.
Chernichenko N; Omelchenko T; Deborde S; Bakst RL; He S; Chen CH; Gusain L; Vakiani E; Katabi N; Hall A; Wong RJ
Mol Cancer Res; 2020 Jun; 18(6):913-925. PubMed ID: 32086369
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