Terms: = Pancreatic cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
29 results:
1. Vav1-dependent rac1 activation mediates hypoxia-induced gemcitabine resistance in pancreatic ductal adenocarcinoma cells through upregulation of HIF-1α expression.
Zhu C; Hu H; Ma Y; Xiong S; Zhu D
Cell Biol Int; 2023 Nov; 47(11):1835-1842. PubMed ID: 37545183
[TBL] [Abstract] [Full Text] [Related]
2. Cytomorphologic, immunophenotypical and molecular features of pancreatic acinar cell carcinoma.
Sun T; Gilani S; Jain D; Cai G
Diagn Cytopathol; 2023 Nov; 51(11):674-683. PubMed ID: 37469257
[TBL] [Abstract] [Full Text] [Related]
3. KRAS
Hobbs GA; Der CJ
Subcell Biochem; 2022; 98():205-221. PubMed ID: 35378710
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4. Mucin 5AC-Mediated CD44/ITGB1 Clustering Mobilizes Adipose-Derived Mesenchymal Stem Cells to Modulate pancreatic cancer Stromal Heterogeneity.
Ganguly K; Cox JL; Ghersi D; Grandgenett PM; Hollingsworth MA; Jain M; Kumar S; Batra SK
Gastroenterology; 2022 Jun; 162(7):2032-2046.e12. PubMed ID: 35219699
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5. Disruption of FDPS/rac1 axis radiosensitizes pancreatic ductal adenocarcinoma by attenuating DNA damage response and immunosuppressive signalling.
Seshacharyulu P; Halder S; Nimmakayala R; Rachagani S; Chaudhary S; Atri P; Chirravuri-Venkata R; Ouellette MM; Carmicheal J; Gautam SK; Vengoji R; Wang S; Li S; Smith L; Talmon GA; Klute K; Ly Q; Reames BN; Grem JL; Berim L; Padussis JC; Kaur S; Kumar S; Ponnusamy MP; Jain M; Lin C; Batra SK
EBioMedicine; 2022 Jan; 75():103772. PubMed ID: 34971971
[TBL] [Abstract] [Full Text] [Related]
6. Mechanical Stress Signaling in pancreatic cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via rac1/cdc42/Myosin II.
Kalli M; Li R; Mills GB; Stylianopoulos T; Zervantonakis IK
Mol Cancer Res; 2022 Mar; 20(3):485-497. PubMed ID: 34782370
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7. PD-1/PD-L1-Associated Immunoarchitectural Patterns Stratify pancreatic cancer Patients into Prognostic/Predictive Subgroups.
Karamitopoulou E; Andreou A; Pahud de Mortanges A; Tinguely M; Gloor B; Perren A
Cancer Immunol Res; 2021 Dec; 9(12):1439-1450. PubMed ID: 34526323
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8. ARHGAP25 Inhibits pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway.
Huang WK; Chen Y; Su H; Chen TY; Gao J; Liu Y; Yeh CN; Li S
Int J Biol Sci; 2021; 17(7):1808-1820. PubMed ID: 33994864
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9. Cullin-3/KCTD10 E3 complex is essential for rac1 activation through RhoB degradation in human epidermal growth factor receptor 2-positive breast cancer cells.
Murakami A; Maekawa M; Kawai K; Nakayama J; Araki N; Semba K; Taguchi T; Kamei Y; Takada Y; Higashiyama S
Cancer Sci; 2019 Feb; 110(2):650-661. PubMed ID: 30515933
[TBL] [Abstract] [Full Text] [Related]
10. Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of pancreatic cancer BxPC-3 Cell Line via a RhoGDI2/rac1/NF-κB Signaling Pathway.
Zhang M; Ding G; Zhou L; Shen T; Xu X; Zhao T; Jia S; Cao L
J Interferon Cytokine Res; 2018 Sep; 38(9):413-422. PubMed ID: 30192158
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11. Serotonin uptake is required for rac1 activation in Kras-induced acinar-to-ductal metaplasia in the pancreas.
Saponara E; Visentin M; Baschieri F; Seleznik G; Martinelli P; Esposito I; Buschmann J; Chen R; Parrotta R; Borgeaud N; Bombardo M; Malagola E; Caflisch A; Farhan H; Graf R; Sonda S
J Pathol; 2018 Nov; 246(3):352-365. PubMed ID: 30058725
[TBL] [Abstract] [Full Text] [Related]
12. PIEZO1 functions as a potential oncogene by promoting cell proliferation and migration in gastric carcinogenesis.
Zhang J; Zhou Y; Huang T; Wu F; Liu L; Kwan JSH; Cheng ASL; Yu J; To KF; Kang W
Mol Carcinog; 2018 Sep; 57(9):1144-1155. PubMed ID: 29683214
[TBL] [Abstract] [Full Text] [Related]
13. TGF-β1-induced cell migration in pancreatic carcinoma cells is rac1 and NOX4-dependent and requires rac1 and NOX4-dependent activation of p38 MAPK.
Witte D; Bartscht T; Kaufmann R; Pries R; Settmacher U; Lehnert H; Ungefroren H
Oncol Rep; 2017 Dec; 38(6):3693-3701. PubMed ID: 29039574
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14. Antibody Binding to CD4 Induces Rac GTPase Activation and Alters T Cell Migration.
Morillon YM; Lessey-Morillon EC; Clark M; Zhang R; Wang B; Burridge K; Tisch R
J Immunol; 2016 Nov; 197(9):3504-3511. PubMed ID: 27694496
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15. rac1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment.
Hein AL; Post CM; Sheinin YM; Lakshmanan I; Natarajan A; Enke CA; Batra SK; Ouellette MM; Yan Y
Oncogene; 2016 Dec; 35(49):6319-6329. PubMed ID: 27181206
[TBL] [Abstract] [Full Text] [Related]
16. Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human pancreatic Carcinoma Cells MIAPaCa-2 via rac1 and RhoA Degradation.
Fujita M; Imadome K; Shoji Y; Isozaki T; Endo S; Yamada S; Imai T
Int J Radiat Oncol Biol Phys; 2015 Sep; 93(1):173-80. PubMed ID: 26279033
[TBL] [Abstract] [Full Text] [Related]
17. Inhibition of rac1 GTPase sensitizes pancreatic cancer cells to γ-irradiation.
Yan Y; Hein AL; Etekpo A; Burchett KM; Lin C; Enke CA; Batra SK; Cowan KH; Ouellette MM
Oncotarget; 2014 Nov; 5(21):10251-70. PubMed ID: 25344910
[TBL] [Abstract] [Full Text] [Related]
18. PI3K regulation of rac1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Wu CY; Carpenter ES; Takeuchi KK; Halbrook CJ; Peverley LV; Bien H; Hall JC; DelGiorno KE; Pal D; Song Y; Shi C; Lin RZ; Crawford HC
Gastroenterology; 2014 Dec; 147(6):1405-16.e7. PubMed ID: 25311989
[TBL] [Abstract] [Full Text] [Related]
19. Saponins extracted from by-product of Asparagus officinalis L. suppress tumour cell migration and invasion through targeting Rho GTPase signalling pathway.
Wang J; Liu Y; Zhao J; Zhang W; Pang X
J Sci Food Agric; 2013 Apr; 93(6):1492-8. PubMed ID: 23450726
[TBL] [Abstract] [Full Text] [Related]
20. Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy.
Kitano A; Shimasaki T; Chikano Y; Nakada M; Hirose M; Higashi T; Ishigaki Y; Endo Y; Takino T; Sato H; Sai Y; Miyamoto K; Motoo Y; Kawakami K; Minamoto T
PLoS One; 2013; 8(2):e55289. PubMed ID: 23408967
[TBL] [Abstract] [Full Text] [Related]
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