Terms: = Pancreatic cancer AND RAF1, Raf-1, 5894, P04049, ENSG00000132155, c-Raf, CRAF
102 results:
1. Disruption of the pro-oncogenic c-raf-PDE8A complex represents a differentiated approach to treating KRAS-c-raf dependent PDAC.
Cooke SF; Wright TA; Sin YY; Ling J; Kyurkchieva E; Phanthaphol N; Mcskimming T; Herbert K; Rebus S; Biankin AV; Chang DK; Baillie GS; Blair CM
Sci Rep; 2024 Apr; 14(1):8998. PubMed ID: 38637546
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2. The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression.
Jin H; Huang X; Pan Q; Ma N; Xie X; Wei Y; Yu F; Wen W; Zhang B; Zhang P; Chen X; Wang J; Liu RY; Lin J; Meng X; Lee MH
Nat Commun; 2024 Mar; 15(1):2551. PubMed ID: 38514606
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3. Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of pancreatic cancer Patient-derived Tumors.
Kazi A; Ranjan A; Kumar M V V; Agianian B; Garcia Chavez M; Vudatha V; Wang R; Vangipurapu R; Chen L; Kennedy P; Subramanian K; Quirke JCK; Beato F; Underwood PW; Fleming JB; Trevino J; Hergenrother PJ; Gavathiotis E; Sebti SM
Cancer Res Commun; 2023 Dec; 3(12):2623-2639. PubMed ID: 38051103
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4. Targeting protein methylation in pancreatic cancer cells results in KRAS signaling imbalance and inhibition of autophagy.
Montenegro MF; Martí-Díaz R; Navarro A; Tolivia J; Sánchez-Del-Campo L; Cabezas-Herrera J; Rodríguez-López JN
Cell Death Dis; 2023 Nov; 14(11):761. PubMed ID: 37996408
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5. A phase I trial of riluzole and sorafenib in patients with advanced solid tumors: CTEP #8850.
Spencer KR; Portal DE; Aisner J; Stein MN; Malhotra J; Shih W; Chan N; Silk AW; Ganesan S; Goodin S; Gounder M; Lin H; Li J; Cerchio R; Marinaro C; Chen S; Mehnert JM
Oncotarget; 2023 Apr; 14():302-315. PubMed ID: 37036756
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6. α4-α5 Helices on Surface of KRAS Can Accommodate Small Compounds That Increase KRAS Signaling While Inducing CRC Cell Death.
Abuasaker B; Garrido E; Vilaplana M; Gómez-Zepeda JD; Brun S; Garcia-Cajide M; Mauvezin C; Jaumot M; Pujol MD; Rubio-Martínez J; Agell N
Int J Mol Sci; 2023 Jan; 24(1):. PubMed ID: 36614192
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7. Germline BRCA2 variants in advanced pancreatic acinar cell carcinoma: A case report and review of literature.
Lee CL; Holter S; Borgida A; Dodd A; Ramotar S; Grant R; Wasson K; Elimova E; Jang RW; Moore M; Kim TK; Khalili K; Moulton CA; Gallinger S; O'Kane GM; Knox JJ
World J Gastroenterol; 2022 Dec; 28(45):6421-6432. PubMed ID: 36533108
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8. AGAP3: A novel BRAF fusion partner in pediatric pancreatic-type acinar cell carcinoma.
Paoli C; Burel-Vandenbos F; Coulomb-l'Hermine A; Cros J; Pondrom M; Kubiniek V; Pedeutour F; Dadone-Montaudié B
Genes Chromosomes Cancer; 2022 Dec; 61(12):734-739. PubMed ID: 35949061
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9. Circ_CDR1as: A circular RNA with roles in the carcinogenesis.
Ghafouri-Fard S; Khoshbakht T; Hussen BM; Sarfaraz S; Taheri M; Ayatollahi SA
Pathol Res Pract; 2022 Aug; 236():153968. PubMed ID: 35667198
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10. Targeting EGFR, RSK1, raf1, PARP2 and LIN28B for several cancer type therapies with newly synthesized pyrazole derivatives via a computational study.
Bennani FE; Doudach L; Karrouchi K; Tarib A; Rudd CE; Ansar M; Faouzi MEA
J Biomol Struct Dyn; 2023 Jun; 41(9):4194-4218. PubMed ID: 35442150
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11. Anticancer drug resistance: An update and perspective.
Nussinov R; Tsai CJ; Jang H
Drug Resist Updat; 2021 Dec; 59():100796. PubMed ID: 34953682
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12. DFMO Improves Survival and Increases Immune Cell Infiltration in Association with MYC Downregulation in the pancreatic Tumor Microenvironment.
Nakkina SP; Gitto SB; Beardsley JM; Pandey V; Rohr MW; Parikh JG; Phanstiel O; Altomare DA
Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34947972
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13. MZF1 mediates oncogene-induced senescence by promoting the transcription of p16
Wu D; Tan H; Su W; Cheng D; Wang G; Wang J; Ma DA; Dong GM; Sun P
Oncogene; 2022 Jan; 41(3):414-426. PubMed ID: 34773072
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14. Retrospective Case Series Analysis of
Hendifar A; Blais EM; Wolpin B; Subbiah V; Collisson E; Singh I; Cannon T; Shaw K; Petricoin EF; Klempner S; Lyons E; Wang-Gillam A; Pishvaian MJ; O'Reilly EM
JCO Precis Oncol; 2021; 5():. PubMed ID: 34476331
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15. The discovery of indolone GW5074 during a comprehensive search for non-polyamine-based polyamine transport inhibitors.
Dobrovolskaite A; Madan M; Pandey V; Altomare DA; Phanstiel O
Int J Biochem Cell Biol; 2021 Sep; 138():106038. PubMed ID: 34252566
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16. LncRNA CERS6-AS1 promotes proliferation and metastasis through the upregulation of YWHAG and activation of ERK signaling in pancreatic cancer.
Xu J; Wang J; He Z; Chen P; Jiang X; Chen Y; Liu X; Jiang J
Cell Death Dis; 2021 Jun; 12(7):648. PubMed ID: 34168120
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17. The crosstalk network of XIST/miR-424-5p/OGT mediates raf1 glycosylation and participates in the progression of liver cancer.
Ning D; Chen J; Du P; Liu Q; Cheng Q; Li X; Zhang B; Chen X; Jiang L
Liver Int; 2021 Aug; 41(8):1933-1944. PubMed ID: 33909326
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18. Dynamic Regulation of Expression of KRAS and Its Effectors Determines the Ability to Initiate Tumorigenesis in pancreatic Acinar Cells.
Assi M; Achouri Y; Loriot A; Dauguet N; Dahou H; Baldan J; Libert M; Fain JS; Guerra C; Bouwens L; Barbacid M; Lemaigre FP; Jacquemin P
Cancer Res; 2021 May; 81(10):2679-2689. PubMed ID: 33602788
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19. circRNA circ_102049 Implicates in pancreatic Ductal Adenocarcinoma Progression through Activating CD80 by Targeting miR-455-3p.
Zhu J; Zhou Y; Zhu S; Li F; Xu J; Zhang L; Shu H
Mediators Inflamm; 2021; 2021():8819990. PubMed ID: 33505218
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20. Accurate and efficient detection of gene fusions from RNA sequencing data.
Uhrig S; Ellermann J; Walther T; Burkhardt P; Fröhlich M; Hutter B; Toprak UH; Neumann O; Stenzinger A; Scholl C; Fröhling S; Brors B
Genome Res; 2021 Mar; 31(3):448-460. PubMed ID: 33441414
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