Terms: = Pancreatic cancer AND SF3B1, ENSG00000115524, 23451, O75533, SF3b155, SAP155, PRPF10, PRP10
13 results:
1. Multiomic Characterization Reveals a Distinct Molecular Landscape in Young-Onset pancreatic cancer.
Ogobuiro I; Baca Y; Ribeiro JR; Walker P; Wilson GC; Gulhati P; Marshall JL; Shroff RT; Spetzler D; Oberley MJ; Abbott DE; Kim HJ; Kooby DA; Maithel SK; Ahmad SA; Merchant NB; Xiu J; Hosein PJ; Datta J
JCO Precis Oncol; 2023 Sep; 7():e2300152. PubMed ID: 37944072
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2. Mutant sf3b1 promotes malignancy in PDAC.
Simmler P; Ioannidi EI; Mengis T; Marquart KF; Asawa S; Van-Lehmann K; Kahles A; Thomas T; Schwerdel C; Aceto N; Rätsch G; Stoffel M; Schwank G
Elife; 2023 Oct; 12():. PubMed ID: 37823551
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3. Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells.
North K; Benbarche S; Liu B; Pangallo J; Chen S; Stahl M; Bewersdorf JP; Stanley RF; Erickson C; Cho H; Pineda JMB; Thomas JD; Polaski JT; Belleville AE; Gabel AM; Udy DB; Humbert O; Kiem HP; Abdel-Wahab O; Bradley RK
Nat Biotechnol; 2022 Jul; 40(7):1103-1113. PubMed ID: 35241838
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4. Dysregulated splicing factor sf3b1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug.
Alors-Perez E; Blázquez-Encinas R; Alcalá S; Viyuela-García C; Pedraza-Arevalo S; Herrero-Aguayo V; Jiménez-Vacas JM; Mafficini A; Sánchez-Frías ME; Cano MT; Abollo-Jiménez F; Marín-Sanz JA; Cabezas-Sainz P; Lawlor RT; Luchini C; Sánchez L; Sánchez-Hidalgo JM; Ventura S; Martin-Hijano L; Gahete MD; Scarpa A; Arjona-Sánchez Á; Ibáñez-Costa A; Sainz B; Luque RM; Castaño JP
J Exp Clin Cancer Res; 2021 Dec; 40(1):382. PubMed ID: 34857016
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5. sf3b1 mutation in pancreatic cancer contributes to aerobic glycolysis and tumor growth through a PP2A-c-Myc axis.
Yang JY; Huo YM; Yang MW; Shen Y; Liu DJ; Fu XL; Tao LY; He RZ; Zhang JF; Hua R; Jiang SH; Sun YW; Liu W
Mol Oncol; 2021 Nov; 15(11):3076-3090. PubMed ID: 33932092
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6. pancreatic ductal adenocarcinomas from Mexican patients present a distinct genomic mutational pattern.
Sanchez P; Espinosa M; Maldonado V; Barquera R; Belem-Gabiño N; Torres J; Cravioto A; Melendez-Zajgla J
Mol Biol Rep; 2020 Jul; 47(7):5175-5184. PubMed ID: 32583281
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7. Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in pancreatic cancer.
Escobar-Hoyos LF; Penson A; Kannan R; Cho H; Pan CH; Singh RK; Apken LH; Hobbs GA; Luo R; Lecomte N; Babu S; Pan FC; Alonso-Curbelo D; Morris JP; Askan G; Grbovic-Huezo O; Ogrodowski P; Bermeo J; Saglimbeni J; Cruz CD; Ho YJ; Lawrence SA; Melchor JP; Goda GA; Bai K; Pastore A; Hogg SJ; Raghavan S; Bailey P; Chang DK; Biankin A; Shroyer KR; Wolpin BM; Aguirre AJ; Ventura A; Taylor B; Der CJ; Dominguez D; Kümmel D; Oeckinghaus A; Lowe SW; Bradley RK; Abdel-Wahab O; Leach SD
Cancer Cell; 2020 Aug; 38(2):198-211.e8. PubMed ID: 32559497
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8. Biliary intraductal tubule-forming neoplasm: a whole exome sequencing study of MUC5AC-positive and -negative cases.
Akita M; Hong SM; Sung YN; Kim MJ; Ajiki T; Fukumoto T; Itoh T; Zen Y
Histopathology; 2020 Jun; 76(7):1005-1012. PubMed ID: 32181510
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9. SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer.
Tian J; Liu Y; Zhu B; Tian Y; Zhong R; Chen W; Lu X; Zou L; Shen N; Qian J; Li H; Miao X; Wang L
Oncotarget; 2015 Nov; 6(35):37750-7. PubMed ID: 26498691
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10. Metastatic disease in uveal melanoma: importance of a genetic profile?
Van Beek JG; Koopmans AE; Vaarwater J; Verdijk RM; de Klein A; Naus NC; Kiliç E
Melanoma Res; 2015 Oct; 25(5):447-9. PubMed ID: 26086698
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11. sf3b1 mutations constitute a novel therapeutic target in breast cancer.
Maguire SL; Leonidou A; Wai P; Marchiò C; Ng CK; Sapino A; Salomon AV; Reis-Filho JS; Weigelt B; Natrajan RC
J Pathol; 2015 Mar; 235(4):571-80. PubMed ID: 25424858
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12. Splicing factor mutations and cancer.
Yoshida K; Ogawa S
Wiley Interdiscip Rev RNA; 2014; 5(4):445-59. PubMed ID: 24523246
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13. pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.
Biankin AV; Waddell N; Kassahn KS; Gingras MC; Muthuswamy LB; Johns AL; Miller DK; Wilson PJ; Patch AM; Wu J; Chang DK; Cowley MJ; Gardiner BB; Song S; Harliwong I; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Gongora M; Pajic M; Scarlett CJ; Gill AJ; Pinho AV; Rooman I; Anderson M; Holmes O; Leonard C; Taylor D; Wood S; Xu Q; Nones K; Fink JL; Christ A; Bruxner T; Cloonan N; Kolle G; Newell F; Pinese M; Mead RS; Humphris JL; Kaplan W; Jones MD; Colvin EK; Nagrial AM; Humphrey ES; Chou A; Chin VT; Chantrill LA; Mawson A; Samra JS; Kench JG; Lovell JA; Daly RJ; Merrett ND; Toon C; Epari K; Nguyen NQ; Barbour A; Zeps N; ; Kakkar N; Zhao F; Wu YQ; Wang M; Muzny DM; Fisher WE; Brunicardi FC; Hodges SE; Reid JG; Drummond J; Chang K; Han Y; Lewis LR; Dinh H; Buhay CJ; Beck T; Timms L; Sam M; Begley K; Brown A; Pai D; Panchal A; Buchner N; De Borja R; Denroche RE; Yung CK; Serra S; Onetto N; Mukhopadhyay D; Tsao MS; Shaw PA; Petersen GM; Gallinger S; Hruban RH; Maitra A; Iacobuzio-Donahue CA; Schulick RD; Wolfgang CL; Morgan RA; Lawlor RT; Capelli P; Corbo V; Scardoni M; Tortora G; Tempero MA; Mann KM; Jenkins NA; Perez-Mancera PA; Adams DJ; Largaespada DA; Wessels LF; Rust AG; Stein LD; Tuveson DA; Copeland NG; Musgrove EA; Scarpa A; Eshleman JR; Hudson TJ; Sutherland RL; Wheeler DA; Pearson JV; McPherson JD; Gibbs RA; Grimmond SM
Nature; 2012 Nov; 491(7424):399-405. PubMed ID: 23103869
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