Terms: = Pancreatic cancer AND SMAD2, MADH2, 4087, ENSG00000175387, MGC34440, MGC22139, hMAD-2, MADR2, JV18-1, hSMAD2, JV18
154 results:
1. Modulating pancreatic cancer microenvironment: The efficacy of Huachansu in mouse models via TGF-β/Smad pathway.
Wang Y; Zhang A; Li Q; Liu C
J Ethnopharmacol; 2024 May; 326():117872. PubMed ID: 38325667
[TBL] [Abstract] [Full Text] [Related]
2. Somatostatin Inhibited the EMT of pancreatic cancer Cells by Mediating the TGF-β/Smad Signaling Pathway.
Zhou X; Wang W; Liu L
Discov Med; 2023 Dec; 35(179):1086-1092. PubMed ID: 38058074
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3. BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells.
Wang X; Song C; Ye Y; Gu Y; Li X; Chen P; Leng D; Xiao J; Wu H; Xie S; Liu W; Zhao Q; Chen D; Chen X; Wu Q; Chen G; Zhang W
Nucleic Acids Res; 2023 Nov; 51(21):11634-11651. PubMed ID: 37870468
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4. BRD9-smad2/3 Orchestrates Stemness and Tumorigenesis in pancreatic Ductal Adenocarcinoma.
Feng Y; Cai L; Pook M; Liu F; Chang CH; Mouti MA; Nibhani R; Militi S; Dunford J; Philpott M; Fan Y; Fan GC; Liu Q; Qi J; Wang C; Hong W; Morgan H; Wang M; Sadayappan S; Jegga AG; Oppermann U; Wang Y; Huang W; Jiang L; Pauklin S
Gastroenterology; 2024 Jan; 166(1):139-154. PubMed ID: 37739089
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5. STAT3 inhibition enhances gemcitabine sensitivity in pancreatic cancer by suppressing EMT, immune escape and inducing oxidative stress damage.
Guo H; Hu Z; Yang X; Yuan Z; Gao Y; Chen J; Xie L; Chen C; Guo Y; Bai Y
Int Immunopharmacol; 2023 Oct; 123():110709. PubMed ID: 37515849
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6. Vactosertib, TGF-β receptor I inhibitor, augments the sensitization of the anti-cancer activity of gemcitabine in pancreatic cancer.
Lee JE; Lee P; Yoon YC; Han BS; Ko S; Park MS; Lee YJ; Kim SE; Cho YJ; Lim JH; Ryu JK; Shim S; Kim DK; Jung KH; Hong SS
Biomed Pharmacother; 2023 Jun; 162():114716. PubMed ID: 37086509
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7. Nodal promotes colorectal cancer survival and metastasis through regulating SCD1-mediated ferroptosis resistance.
Wu T; Wan J; Qu X; Xia K; Wang F; Zhang Z; Yang M; Wu X; Gao R; Yuan X; Fang L; Chen C; Yin L
Cell Death Dis; 2023 Mar; 14(3):229. PubMed ID: 37002201
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8. Establishment and Molecular Characterization of Two Patient-Derived pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for Treatment Response.
Braun R; Lapshyna O; Watzelt J; Drenckhan M; Künstner A; Färber B; Hael AAM; Bolm L; Honselmann KC; Konukiewitz B; Castven D; Spielmann M; Gorantla SP; Busch H; Marquardt JU; Keck T; Wellner UF; Ungefroren H
Cells; 2023 Feb; 12(4):. PubMed ID: 36831254
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9. Epigenome-wide association analysis of pancreatic exocrine cells from high-fat- and normal diet-fed mice and its potential use for understanding the oncogenesis of human pancreatic cancer.
Araki T; Nagashima M; Hirasawa H; Tamalu F; Katagiri Y; Miwa N
Biochem Biophys Res Commun; 2022 Dec; 637():50-57. PubMed ID: 36375250
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10. smad2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4.
Bertrand-Chapel A; Caligaris C; Fenouil T; Savary C; Aires S; Martel S; Huchedé P; Chassot C; Chauvet V; Cardot-Ruffino V; Morel AP; Subtil F; Mohkam K; Mabrut JY; Tonon L; Viari A; Cassier P; Hervieu V; Castets M; Mauviel A; Sentis S; Bartholin L
Commun Biol; 2022 Oct; 5(1):1068. PubMed ID: 36207615
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11. Hyperthermia-induced stellate cell deactivation to enhance dual chemo and pH-responsive photothermal therapy for pancreatic cancers.
Hu Q; Xu M; Feng J; Xie H; Li J; He Y; Tang G; Guo B
Nanoscale; 2022 Nov; 14(42):15735-15748. PubMed ID: 36205175
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12. TRPC1 channels regulate the activation of pancreatic stellate cells through ERK1/2 and smad2 pathways and perpetuate their pressure-mediated activation.
Radoslavova S; Fels B; Pethö Z; Gruner M; Ruck T; Meuth SG; Folcher A; Prevarskaya N; Schwab A; Ouadid-Ahidouch H
Cell Calcium; 2022 Sep; 106():102621. PubMed ID: 35905654
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13. Golgi scaffold protein PAQR3 as a candidate suppressor of gastric cardia adenocarcinoma via regulating TGF-β/Smad pathway.
Wu YL; Hong LL; Ling ZN; Hu XY; Liu Z; Li P; Ling ZQ
J Clin Lab Anal; 2022 Sep; 36(9):e24617. PubMed ID: 35870178
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14. cancer-Associated Fibroblast-Targeted Delivery of Captopril to Overcome Penetration Obstacles for Enhanced pancreatic cancer Therapy.
Chen X; Jia F; Huang Y; Jin Q; Ji J
ACS Appl Bio Mater; 2022 Jul; 5(7):3544-3553. PubMed ID: 35786827
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15. Rhoifolin from Plumula Nelumbinis exhibits anti-cancer effects in pancreatic cancer via AKT/JNK signaling pathways.
Zheng B; Zheng Y; Zhang N; Zhang Y; Zheng B
Sci Rep; 2022 Apr; 12(1):5654. PubMed ID: 35383226
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16. Curcumol inhibits the growth of xenograft-tumors in mice and the biological activities of pancreatic cancer cells by regulating the miR-21-5p/SMAD7 axis.
Fang S; Wang L; Luo C; Yi H; Wang X; Ning B
Cell Cycle; 2022 Jun; 21(12):1249-1266. PubMed ID: 35253605
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17. Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer.
Sheng W; Tang J; Cao R; Shi X; Ma Y; Dong M
Cell Death Dis; 2022 Feb; 13(2):173. PubMed ID: 35197444
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18. Overexpressed integrin alpha 2 inhibits the activation of the transforming growth factor β pathway in pancreatic cancer via the TFCP2-smad2 axis.
Cai H; Guo F; Wen S; Jin X; Wu H; Ren D
J Exp Clin Cancer Res; 2022 Feb; 41(1):73. PubMed ID: 35193647
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19. Transforming growth factor-β challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells.
Zhang J; Zhang Z; Holst S; Blöchl C; Madunic K; Wuhrer M; Ten Dijke P; Zhang T
J Biol Chem; 2022 Mar; 298(3):101717. PubMed ID: 35151689
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20. Tumor-stroma TGF-β1-THBS2 feedback circuit drives pancreatic ductal adenocarcinoma progression via integrin α
Nan P; Dong X; Bai X; Lu H; Liu F; Sun Y; Zhao X
Cancer Lett; 2022 Mar; 528():59-75. PubMed ID: 34958892
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