BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND SMAD2, MADH2, 4087, ENSG00000175387, MGC34440, MGC22139, hMAD-2, MADR2, JV18-1, hSMAD2, JV18 AND Prognosis
23 results:

  • 1. BRD9-smad2/3 Orchestrates Stemness and Tumorigenesis in pancreatic Ductal Adenocarcinoma.
    Feng Y; Cai L; Pook M; Liu F; Chang CH; Mouti MA; Nibhani R; Militi S; Dunford J; Philpott M; Fan Y; Fan GC; Liu Q; Qi J; Wang C; Hong W; Morgan H; Wang M; Sadayappan S; Jegga AG; Oppermann U; Wang Y; Huang W; Jiang L; Pauklin S
    Gastroenterology; 2024 Jan; 166(1):139-154. PubMed ID: 37739089
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. STAT3 inhibition enhances gemcitabine sensitivity in pancreatic cancer by suppressing EMT, immune escape and inducing oxidative stress damage.
    Guo H; Hu Z; Yang X; Yuan Z; Gao Y; Chen J; Xie L; Chen C; Guo Y; Bai Y
    Int Immunopharmacol; 2023 Oct; 123():110709. PubMed ID: 37515849
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Establishment and Molecular Characterization of Two Patient-Derived pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for Treatment Response.
    Braun R; Lapshyna O; Watzelt J; Drenckhan M; Künstner A; Färber B; Hael AAM; Bolm L; Honselmann KC; Konukiewitz B; Castven D; Spielmann M; Gorantla SP; Busch H; Marquardt JU; Keck T; Wellner UF; Ungefroren H
    Cells; 2023 Feb; 12(4):. PubMed ID: 36831254
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. smad2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4.
    Bertrand-Chapel A; Caligaris C; Fenouil T; Savary C; Aires S; Martel S; Huchedé P; Chassot C; Chauvet V; Cardot-Ruffino V; Morel AP; Subtil F; Mohkam K; Mabrut JY; Tonon L; Viari A; Cassier P; Hervieu V; Castets M; Mauviel A; Sentis S; Bartholin L
    Commun Biol; 2022 Oct; 5(1):1068. PubMed ID: 36207615
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Golgi scaffold protein PAQR3 as a candidate suppressor of gastric cardia adenocarcinoma via regulating TGF-β/Smad pathway.
    Wu YL; Hong LL; Ling ZN; Hu XY; Liu Z; Li P; Ling ZQ
    J Clin Lab Anal; 2022 Sep; 36(9):e24617. PubMed ID: 35870178
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Transforming growth factor-β challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells.
    Zhang J; Zhang Z; Holst S; Blöchl C; Madunic K; Wuhrer M; Ten Dijke P; Zhang T
    J Biol Chem; 2022 Mar; 298(3):101717. PubMed ID: 35151689
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Tumor-stroma TGF-β1-THBS2 feedback circuit drives pancreatic ductal adenocarcinoma progression via integrin α
    Nan P; Dong X; Bai X; Lu H; Liu F; Sun Y; Zhao X
    Cancer Lett; 2022 Mar; 528():59-75. PubMed ID: 34958892
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Prognostic value of small mother against decapentaplegic expression in human gastric cancer.
    Zhang HW; Guo Y; Sun LX; Ni FB; Xu K
    Bioengineered; 2021 Dec; 12(1):2534-2549. PubMed ID: 34138687
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/smad2/3 pathway and ABCC1 transactivation.
    Wei L; Lin Q; Lu Y; Li G; Huang L; Fu Z; Chen R; Zhou Q
    Cell Death Dis; 2021 Mar; 12(4):334. PubMed ID: 33782384
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. SMAD4 mutation correlates with poor prognosis in non-small cell lung cancer.
    Wang Y; Xue Q; Zheng Q; Jin Y; Shen X; Yang M; Zhou X; Li Y
    Lab Invest; 2021 Apr; 101(4):463-476. PubMed ID: 33303972
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Quercetin suppresses pancreatic ductal adenocarcinoma progression via inhibition of SHH and TGF-β/Smad signaling pathways.
    Guo Y; Tong Y; Zhu H; Xiao Y; Guo H; Shang L; Zheng W; Ma S; Liu X; Bai Y
    Cell Biol Toxicol; 2021 Jun; 37(3):479-496. PubMed ID: 33070227
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. MicroRNA-148a-3p inhibits progression of hepatocelluar carcimoma by repressing smad2 expression in an Ago2 dependent manner.
    Huang Z; Wen J; Yu J; Liao J; Liu S; Cai N; Liang H; Chen X; Ding Z; Zhang B
    J Exp Clin Cancer Res; 2020 Aug; 39(1):150. PubMed ID: 32746934
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Establishment of a 7-miRNA-Based Risk Score System for Predicting prognosis of pancreatic cancer.
    Zhuang H; Ma Z; Huang K; Zhou Z; Huang B; Sun Z; Hou B; Zhang C
    Pancreas; 2020; 49(5):655-662. PubMed ID: 32433403
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. TGF-β1 secreted by pancreatic stellate cells promotes stemness and tumourigenicity in pancreatic cancer cells through L1CAM downregulation.
    Cave DD; Di Guida M; Costa V; Sevillano M; Ferrante L; Heeschen C; Corona M; Cucciardi A; Lonardo E
    Oncogene; 2020 May; 39(21):4271-4285. PubMed ID: 32291413
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Effects of ME3 on the proliferation, invasion and metastasis of pancreatic cancer cells through epithelial-mesenchymal transition.
    Zhang Q; Li J; Tan XP; Zhao Q
    Neoplasma; 2019 Nov; 66(6):896-907. PubMed ID: 31607129
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Macrophage-expressed CD51 promotes cancer stem cell properties via the TGF-β1/smad2/3 axis in pancreatic cancer.
    Zhang B; Ye H; Ren X; Zheng S; Zhou Q; Chen C; Lin Q; Li G; Wei L; Fu Z; Zhang Y; Hu C; Li Z; Chen R
    Cancer Lett; 2019 Sep; 459():204-215. PubMed ID: 31199988
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Identification of gene expression models for laryngeal squamous cell carcinoma using co-expression network analysis.
    Yang CW; Wang SF; Yang XL; Wang L; Niu L; Liu JX
    Medicine (Baltimore); 2018 Feb; 97(7):e9738. PubMed ID: 29443735
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Adrenaline promotes epithelial-to-mesenchymal transition via HuR-TGFβ regulatory axis in pancreatic cancer cells and the implication in cancer prognosis.
    Pu J; Zhang X; Luo H; Xu L; Lu X; Lu J
    Biochem Biophys Res Commun; 2017 Nov; 493(3):1273-1279. PubMed ID: 28965949
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Significance of positive and inhibitory regulators in the TGF-β signaling pathway in colorectal cancers.
    Coates RF; Gardner JA; Gao Y; Cortright VM; Mitchell JM; Ashikaga T; Skelly J; Yang MX
    Hum Pathol; 2017 Aug; 66():34-39. PubMed ID: 28601657
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Methyl-CpG-binding domain 3 inhibits epithelial-mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling.
    Xu M; He J; Li J; Feng W; Zhou H; Wei H; Zhou M; Lu Y; Zeng J; Peng W; Du F; Gong A
    Br J Cancer; 2017 Jan; 116(1):91-99. PubMed ID: 27898661
    [TBL] [Abstract] [Full Text] [Related]  


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