Terms: = Pancreatic cancer AND SMAD2, MADH2, 4087, ENSG00000175387, MGC34440, MGC22139, hMAD-2, MADR2, JV18-1, hSMAD2, JV18 AND Treatment
36 results:
1. Modulating pancreatic cancer microenvironment: The efficacy of Huachansu in mouse models via TGF-β/Smad pathway.
Wang Y; Zhang A; Li Q; Liu C
J Ethnopharmacol; 2024 May; 326():117872. PubMed ID: 38325667
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2. BRD9-smad2/3 Orchestrates Stemness and Tumorigenesis in pancreatic Ductal Adenocarcinoma.
Feng Y; Cai L; Pook M; Liu F; Chang CH; Mouti MA; Nibhani R; Militi S; Dunford J; Philpott M; Fan Y; Fan GC; Liu Q; Qi J; Wang C; Hong W; Morgan H; Wang M; Sadayappan S; Jegga AG; Oppermann U; Wang Y; Huang W; Jiang L; Pauklin S
Gastroenterology; 2024 Jan; 166(1):139-154. PubMed ID: 37739089
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3. STAT3 inhibition enhances gemcitabine sensitivity in pancreatic cancer by suppressing EMT, immune escape and inducing oxidative stress damage.
Guo H; Hu Z; Yang X; Yuan Z; Gao Y; Chen J; Xie L; Chen C; Guo Y; Bai Y
Int Immunopharmacol; 2023 Oct; 123():110709. PubMed ID: 37515849
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4. Vactosertib, TGF-β receptor I inhibitor, augments the sensitization of the anti-cancer activity of gemcitabine in pancreatic cancer.
Lee JE; Lee P; Yoon YC; Han BS; Ko S; Park MS; Lee YJ; Kim SE; Cho YJ; Lim JH; Ryu JK; Shim S; Kim DK; Jung KH; Hong SS
Biomed Pharmacother; 2023 Jun; 162():114716. PubMed ID: 37086509
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5. Nodal promotes colorectal cancer survival and metastasis through regulating SCD1-mediated ferroptosis resistance.
Wu T; Wan J; Qu X; Xia K; Wang F; Zhang Z; Yang M; Wu X; Gao R; Yuan X; Fang L; Chen C; Yin L
Cell Death Dis; 2023 Mar; 14(3):229. PubMed ID: 37002201
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6. Establishment and Molecular Characterization of Two Patient-Derived pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for treatment Response.
Braun R; Lapshyna O; Watzelt J; Drenckhan M; Künstner A; Färber B; Hael AAM; Bolm L; Honselmann KC; Konukiewitz B; Castven D; Spielmann M; Gorantla SP; Busch H; Marquardt JU; Keck T; Wellner UF; Ungefroren H
Cells; 2023 Feb; 12(4):. PubMed ID: 36831254
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7. Hyperthermia-induced stellate cell deactivation to enhance dual chemo and pH-responsive photothermal therapy for pancreatic cancers.
Hu Q; Xu M; Feng J; Xie H; Li J; He Y; Tang G; Guo B
Nanoscale; 2022 Nov; 14(42):15735-15748. PubMed ID: 36205175
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8. Transforming growth factor-β challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells.
Zhang J; Zhang Z; Holst S; Blöchl C; Madunic K; Wuhrer M; Ten Dijke P; Zhang T
J Biol Chem; 2022 Mar; 298(3):101717. PubMed ID: 35151689
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9. Determining oncogenic patterns and cancer predisposition through the transcriptomic profile in Mitchell-Riley syndrome with heterotopic gastric mucosa and duodenal atresia: a case report.
Calcaterra V; Chiricosta L; Mazzon E; Gugnandolo A; Alberti D; Maestri L; Meroni M; Vestri E; Verduci E; Dilillo D; Zuccotti G; Pelizzo G
Orphanet J Rare Dis; 2021 Oct; 16(1):455. PubMed ID: 34715892
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10. Prognostic value of small mother against decapentaplegic expression in human gastric cancer.
Zhang HW; Guo Y; Sun LX; Ni FB; Xu K
Bioengineered; 2021 Dec; 12(1):2534-2549. PubMed ID: 34138687
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11. FUBP1 mediates the growth and metastasis through TGFβ/Smad signaling in pancreatic adenocarcinoma.
Zhang Y; Chen J; Zhou N; Lu Y; Lu J; Xing X; Chen H; Zhang X
Int J Mol Med; 2021 May; 47(5):. PubMed ID: 33649780
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12. TGFB1/INHBA Homodimer/Nodal-smad2/3 Signaling Network: A Pivotal Molecular Target in PDAC treatment.
Abdel Mouti M; Pauklin S
Mol Ther; 2021 Mar; 29(3):920-936. PubMed ID: 33429081
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13. Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition.
Xiong C; Zhu Y; Xue M; Jiang Y; Zhong Y; Jiang L; Shi M; Chen H
Aging (Albany NY); 2021 Jan; 13(3):3386-3404. PubMed ID: 33428605
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14. Quercetin suppresses pancreatic ductal adenocarcinoma progression via inhibition of SHH and TGF-β/Smad signaling pathways.
Guo Y; Tong Y; Zhu H; Xiao Y; Guo H; Shang L; Zheng W; Ma S; Liu X; Bai Y
Cell Biol Toxicol; 2021 Jun; 37(3):479-496. PubMed ID: 33070227
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15. Obg-like ATPase 1 inhibited oral carcinoma cell metastasis through TGFβ/smad2 axis in vitro.
Liu J; Yang Q; Xiao KC; Dobleman T; Hu S; Xiao GG
BMC Mol Cell Biol; 2020 Sep; 21(1):65. PubMed ID: 32928102
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16. Metformin inhibits TGF‑β1‑induced epithelial‑mesenchymal transition and liver metastasis of pancreatic cancer cells.
Yoshida J; Ishikawa T; Endo Y; Matsumura S; Ota T; Mizushima K; Hirai Y; Oka K; Okayama T; Sakamoto N; Inoue K; Kamada K; Uchiyama K; Takagi T; Naito Y; Itoh Y
Oncol Rep; 2020 Jul; 44(1):371-381. PubMed ID: 32627027
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17. Identification of new candidate genes and signalling pathways associated with the development of neuroendocrine pancreatic tumours based on next generation sequencing data.
Kit OI; Trifanov VS; Petrusenko NA; Gvaldin DY; Kutilin DS; Timoshkina NN
Mol Biol Rep; 2020 Jun; 47(6):4233-4243. PubMed ID: 32451928
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18. Effects of ME3 on the proliferation, invasion and metastasis of pancreatic cancer cells through epithelial-mesenchymal transition.
Zhang Q; Li J; Tan XP; Zhao Q
Neoplasma; 2019 Nov; 66(6):896-907. PubMed ID: 31607129
[TBL] [Abstract] [Full Text] [Related]
19. B7-1 drives TGF-β stimulated pancreatic carcinoma cell migration and expression of EMT target genes.
Kang JH; Jung MY; Leof EB
PLoS One; 2019; 14(9):e0222083. PubMed ID: 31483844
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20. Silencing of DLEU2 suppresses pancreatic cancer cell proliferation and invasion by upregulating microRNA-455.
Xu B; Gong X; Zi L; Li G; Dong S; Chen X; Li Y
Cancer Sci; 2019 May; 110(5):1676-1685. PubMed ID: 30838724
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