BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND SMAD3, JV15-2, 4088, ENSG00000166949, P84022, Smad3, MADH3, HsT17436, Smad 3, DKFZp686J10186, HSPC193, DKFZP586N0721, MGC60396 AND Treatment
33 results:

  • 1. TGF-β1/smad3-driven GLI2 isoform expression contributes to aggressive phenotypes of hepatocellular carcinoma.
    Ding J; Yang YY; Li PT; Ma Y; Zhang L; Zhou Y; Jin C; Li HY; Zhu YF; Liu XP; Liu ZJ; Jia HL; Liu PG; Wu J
    Cancer Lett; 2024 Apr; 588():216768. PubMed ID: 38453045
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Modulating pancreatic cancer microenvironment: The efficacy of Huachansu in mouse models via TGF-β/smad pathway.
    Wang Y; Zhang A; Li Q; Liu C
    J Ethnopharmacol; 2024 May; 326():117872. PubMed ID: 38325667
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. An NFATc1/smad3/cJUN Complex Restricted to smad4-Deficient pancreatic cancer Guides Rational Therapies.
    Hasselluhn MC; Schlösser D; Versemann L; Schmidt GE; Ulisse M; Oschwald J; Zhang Z; Hamdan F; Xiao H; Kopp W; Spitalieri J; Kellner C; Schneider C; Reutlinger K; Nagarajan S; Steuber B; Sastra SA; Palermo CF; Appelhans J; Bohnenberger H; Todorovic J; Kostyuchek I; Ströbel P; Bockelmann A; König A; Ammer-Herrmenau C; Schmidleitner L; Kaulfuß S; Wollnik B; Hahn SA; Neesse A; Singh SK; Bastians H; Reichert M; Sax U; Olive KP; Johnsen SA; Schneider G; Ellenrieder V; Hessmann E
    Gastroenterology; 2024 Feb; 166(2):298-312.e14. PubMed ID: 37913894
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. AZGP1 activation by lenvatinib suppresses intrahepatic cholangiocarcinoma epithelial-mesenchymal transition through the TGF-β1/smad3 pathway.
    Deng L; Bao W; Zhang B; Zhang S; Chen Z; Zhu X; He B; Wu L; Chen X; Deng T; Chen B; Yu Z; Wang Y; Chen G
    Cell Death Dis; 2023 Sep; 14(9):590. PubMed ID: 37669935
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art.
    Lu G; Wang X; Cheng M; Wang S; Ma K
    Biomed Pharmacother; 2023 Sep; 165():115132. PubMed ID: 37423169
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Long-term (10-year) outcomes and prognostic factors in resected intraductal papillary mucinous neoplasm tumors in Finland: A nationwide retrospective study.
    Vaalavuo Y; Vornanen M; Ahola R; Antila A; Rinta-Kiikka I; Sand J; Laukkarinen J
    Surgery; 2023 Jul; 174(1):75-82. PubMed ID: 37062604
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Hyperthermia-induced stellate cell deactivation to enhance dual chemo and pH-responsive photothermal therapy for pancreatic cancers.
    Hu Q; Xu M; Feng J; Xie H; Li J; He Y; Tang G; Guo B
    Nanoscale; 2022 Nov; 14(42):15735-15748. PubMed ID: 36205175
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. TGF-β1/smad3 upregulates UCA1 to promote liver fibrosis through DKK1 and miR18a.
    Yang Z; Zhang H; Yin M; Cheng Z; Jiang P; Feng M; Liu Z; Liao B
    J Mol Med (Berl); 2022 Oct; 100(10):1465-1478. PubMed ID: 36001113
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Prognostic value of small mother against decapentaplegic expression in human gastric cancer.
    Zhang HW; Guo Y; Sun LX; Ni FB; Xu K
    Bioengineered; 2021 Dec; 12(1):2534-2549. PubMed ID: 34138687
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. EEF1A2 interacts with HSP90AB1 to promote lung adenocarcinoma metastasis via enhancing TGF-β/smad signalling.
    Jia L; Ge X; Du C; Chen L; Zhou Y; Xiong W; Xiang J; Li G; Xiao G; Fang L; Li Z
    Br J Cancer; 2021 Mar; 124(7):1301-1311. PubMed ID: 33473168
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. TOPK promotes epithelial-mesenchymal transition and invasion of breast cancer cells through upregulation of TBX3 in TGF-β1/smad signaling.
    Lee YJ; Park JH; Oh SM
    Biochem Biophys Res Commun; 2020 Jan; 522(1):270-277. PubMed ID: 31757421
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. DEPTOR induces a partial epithelial-to-mesenchymal transition and metastasis via autocrine TGFβ1 signaling and is associated with poor prognosis in hepatocellular carcinoma.
    Chen J; Zhu H; Liu Q; Ning D; Zhang Z; Zhang L; Mo J; Du P; Liu X; Song S; Fan Y; Liang H; Liu J; Zhang B; Chen X
    J Exp Clin Cancer Res; 2019 Jun; 38(1):273. PubMed ID: 31228948
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer.
    Luo K; Geng J; Zhang Q; Xu Y; Zhou X; Huang Z; Shi KQ; Pan C; Wu J
    J Exp Clin Cancer Res; 2019 Jun; 38(1):249. PubMed ID: 31186036
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion.
    Jiang H; Liu X; Knolhoff BL; Hegde S; Lee KB; Jiang H; Fields RC; Pachter JA; Lim KH; DeNardo DG
    Gut; 2020 Jan; 69(1):122-132. PubMed ID: 31076405
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence.
    Shi JH; Guo WZ; Jin Y; Zhang HP; Pang C; Li J; Line PD; Zhang SJ
    Cancer Med; 2019 Mar; 8(3):1269-1278. PubMed ID: 30714677
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Exosomes derived from human umbilical cord mesenchymal stromal cells deliver exogenous miR-145-5p to inhibit pancreatic ductal adenocarcinoma progression.
    Ding Y; Cao F; Sun H; Wang Y; Liu S; Wu Y; Cui Q; Mei W; Li F
    Cancer Lett; 2019 Feb; 442():351-361. PubMed ID: 30419348
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification.
    He RQ; Wu PR; Xiang XL; Yang X; Liang HW; Qiu XH; Yang LH; Peng ZG; Chen G
    Int J Mol Med; 2018 May; 41(5):2813-2831. PubMed ID: 29484429
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Galangin enhances TGF-β1-mediated growth inhibition by suppressing phosphorylation of threonine 179 residue in smad3 linker region.
    Kwak MK; Yang KM; Park J; Lee S; Park Y; Hong E; Sun EJ; An H; Park S; Pang K; Lee J; Kang JM; Kim P; Ooshima A; Kim SJ
    Biochem Biophys Res Commun; 2017 Dec; 494(3-4):706-713. PubMed ID: 29097203
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. The TGFβ-smad3 pathway inhibits IL-1α induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration.
    Tjomsland V; Sandnes D; Pomianowska E; Cizmovic ST; Aasrum M; Brusevold IJ; Christoffersen T; Gladhaug IP
    J Exp Clin Cancer Res; 2016 Jul; 35(1):122. PubMed ID: 27473228
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. LB-100 sensitizes hepatocellular carcinoma cells to the effects of sorafenib during hypoxia by activation of smad3 phosphorylation.
    Fu QH; Zhang Q; Zhang JY; Sun X; Lou Y; Li GG; Chen ZL; Bai XL; Liang TB
    Tumour Biol; 2016 Jun; 37(6):7277-86. PubMed ID: 26666823
    [TBL] [Abstract] [Full Text] [Related]  


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