BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND SMAD4, JIP, Q13485, 4089, ENSG00000141646, MADH4, DPC4
789 results:

  • 1. Undifferentiated Carcinoma with Osteoclast-like Giant Cells of the Pancreas: Molecular Genetic Analysis of 13 Cases.
    Hrudka J; Kalinová M; Ciprová V; Moravcová J; Dvořák R; Matěj R
    Int J Mol Sci; 2024 Mar; 25(6):. PubMed ID: 38542259
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting smad4.
    Li Z; Ma Z; Wang S; Yan Q; Zhuang H; Zhou Z; Liu C; Chen Y; Han M; Wu Z; Huang S; Zhou Q; Hou B; Zhang C
    Biol Direct; 2024 Mar; 19(1):24. PubMed ID: 38504385
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  • 3. Assessing the genomic feature of Chinese patients with ampullary adenocarcinoma: potential therapeutic targets.
    Dong Z; Chong W; Chen C; Qi L; Mengke L; Minghui D; Jiawei Y; Longxi Q; Hengchao L; Liu J; Zhimin G
    BMC Cancer; 2024 Mar; 24(1):286. PubMed ID: 38439030
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. High somatic mutations in circulating tumor DNA predict response of metastatic pancreatic ductal adenocarcinoma to first-line nab-paclitaxel plus S-1: prospective study.
    Huang L; Lv Y; Guan S; Yan H; Han L; Wang Z; Han Q; Dai G; Shi Y
    J Transl Med; 2024 Feb; 22(1):184. PubMed ID: 38378604
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Modulating pancreatic cancer microenvironment: The efficacy of Huachansu in mouse models via TGF-β/Smad pathway.
    Wang Y; Zhang A; Li Q; Liu C
    J Ethnopharmacol; 2024 May; 326():117872. PubMed ID: 38325667
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  • 6. TGFβ and Hippo Signaling Pathways Coordinate to Promote Acinar to Ductal Metaplasia in Human Pancreas.
    Nipper M; Xu Y; Liu J; Yin X; Liu Z; Ye Z; Zhang J; Chen Y; Wang P
    Cells; 2024 Jan; 13(2):. PubMed ID: 38247878
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  • 7. Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma.
    Abe S; Masuda A; Matsumoto T; Inoue J; Toyama H; Sakai A; Kobayashi T; Tanaka T; Tsujimae M; Yamakawa K; Gonda M; Masuda S; Uemura H; Kohashi S; Inomata N; Nagao K; Harada Y; Miki M; Irie Y; Juri N; Ko T; Yokotani Y; Oka Y; Ota S; Kanzawa M; Itoh T; Imai T; Fukumoto T; Hara E; Kodama Y
    J Gastroenterol; 2024 Mar; 59(3):250-262. PubMed ID: 38242997
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Successful immunotherapy with PD-1 Iinhibitor for advanced pancreatic cancer: report of two cases and review of literature.
    Qiu L; Liu C; Li H
    Anticancer Drugs; 2024 Mar; 35(3):263-270. PubMed ID: 38194502
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Molecular characteristics of early-onset pancreatic ductal adenocarcinoma.
    Debernardi S; Liszka L; Ntala C; Steiger K; Esposito I; Carlotti E; Baker AM; McDonald S; Graham T; Dmitrovic B; Feakins RM; Crnogorac-Jurcevic T
    Mol Oncol; 2024 Mar; 18(3):677-690. PubMed ID: 38145461
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  • 10. Prioritization of Fluorescence In Situ Hybridization (FISH) Probes for Differentiating Primary Sites of Neuroendocrine Tumors with Machine Learning.
    Pietan L; Vaughn H; Howe JR; Bellizzi AM; Smith BJ; Darbro B; Braun T; Casavant T
    Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139230
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Precision medicine for KRAS wild-type pancreatic adenocarcinomas.
    Ben-Ammar I; Rousseau A; Nicolle R; Tarabay A; Boige V; Valery M; Pudlarz T; Malka D; Gelli M; Fernandez-De-Sevilla E; Fuerea A; Tanguy ML; Rouleau E; Barbe R; Mathieu JRR; Jaulin F; Smolenschi C; Hollebecque A; Ducreux M; Boileve A
    Eur J Cancer; 2024 Jan; 197():113497. PubMed ID: 38134480
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling.
    Xiao M; Wang F; Chen N; Zhang H; Cao J; Yu Y; Zhao B; Ji J; Xu P; Li L; Shen L; Lin X; Feng XH
    Dev Cell; 2024 Jan; 59(1):48-63.e8. PubMed ID: 38103553
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. smad4 endows TGF-β1-induced highly invasive tumor cells with ferroptosis vulnerability in pancreatic cancer.
    Chen HD; Ye Z; Hu HF; Fan GX; Hu YH; Li Z; Li BR; Ji SR; Zhou CJ; Xu XW; Yu XJ; Qin Y
    Acta Pharmacol Sin; 2024 Apr; 45(4):844-856. PubMed ID: 38057506
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Prognostic Value and the Immune Microenvironment-associated Role of
    Song Y; Wang Y; Yu T; He Y; Wang C; Wang F; Zhou Y
    Anticancer Res; 2023 Dec; 43(12):5393-5408. PubMed ID: 38030175
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. High overall copy number variation burden by genome-wide methylation profiling holds negative prognostic value in surgically treated pancreatic ductal adenocarcinoma.
    Detlefsen S; Boldt HB; Burton M; Thomsen MM; Rasmussen LG; Ørbeck SV; Pfeiffer P; Mortensen MB; de Stricker K
    Hum Pathol; 2023 Dec; 142():68-80. PubMed ID: 37977512
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Multiomic Characterization Reveals a Distinct Molecular Landscape in Young-Onset pancreatic cancer.
    Ogobuiro I; Baca Y; Ribeiro JR; Walker P; Wilson GC; Gulhati P; Marshall JL; Shroff RT; Spetzler D; Oberley MJ; Abbott DE; Kim HJ; Kooby DA; Maithel SK; Ahmad SA; Merchant NB; Xiu J; Hosein PJ; Datta J
    JCO Precis Oncol; 2023 Sep; 7():e2300152. PubMed ID: 37944072
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. An NFATc1/SMAD3/cJUN Complex Restricted to smad4-Deficient pancreatic cancer Guides Rational Therapies.
    Hasselluhn MC; Schlösser D; Versemann L; Schmidt GE; Ulisse M; Oschwald J; Zhang Z; Hamdan F; Xiao H; Kopp W; Spitalieri J; Kellner C; Schneider C; Reutlinger K; Nagarajan S; Steuber B; Sastra SA; Palermo CF; Appelhans J; Bohnenberger H; Todorovic J; Kostyuchek I; Ströbel P; Bockelmann A; König A; Ammer-Herrmenau C; Schmidleitner L; Kaulfuß S; Wollnik B; Hahn SA; Neesse A; Singh SK; Bastians H; Reichert M; Sax U; Olive KP; Johnsen SA; Schneider G; Ellenrieder V; Hessmann E
    Gastroenterology; 2024 Feb; 166(2):298-312.e14. PubMed ID: 37913894
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. AKT and mTOR expression in human pancreatic ductal adenocarcinoma. Relevance for tumor biology.
    Handra-Luca A
    Pathol Res Pract; 2023 Nov; 251():154878. PubMed ID: 37890271
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Gene Rearrangement and Expression of PRKACA and PRKACB Govern Morphobiology of Pancreatobiliary Oncocytic Neoplasms.
    Itoh T; Omori Y; Seino M; Hirose K; Date F; Ono Y; Mizukami Y; Aoki S; Ishida M; Mizuma M; Morikawa T; Higuchi R; Honda G; Okamura Y; Kinoshita K; Unno M; Furukawa T
    Mod Pathol; 2024 Jan; 37(1):100358. PubMed ID: 37871652
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. smad4 loss predicts worse overall and distant metastasis-free survival in patients with resected pancreatic adenocarcinoma.
    Anstadt EJ; Carmona R; Berlin E; Yegya-Raman N; Venigalla S; Reddy V; Williams GR; Leibensperger MR; Wojcieszynski A; Baumann BC; Lee MK; Plastaras JP; Furth EE; Mell LK; Metz JM; Ben-Josef E
    Cancer; 2024 Feb; 130(3):476-484. PubMed ID: 37823514
    [TBL] [Abstract] [Full Text] [Related]  


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