Terms: = Pancreatic cancer AND SMO, Q99835, 6608, ENSG00000128602, SMOH, Gx AND Treatment
32 results:
1. Elucidating the Role of miRNA-326 Modulating Hedgehog Signaling in pancreatic Carcinoma.
Rashid S; Rashid S; Das P; Malik N; Dash NR; Singh N; Pandey RM; Kumar L; Chauhan SS; Chosdol K; Gupta S; Saraya A
Pancreas; 2024 Jan; 53(1):e42-e48. PubMed ID: 38019614
[TBL] [Abstract] [Full Text] [Related]
2. Emerging Roles of Hedgehog Signaling in cancer Immunity.
Giammona A; Crivaro E; Stecca B
Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36674836
[TBL] [Abstract] [Full Text] [Related]
3. Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation.
Li L; Bao J; Wang H; Lei JH; Peng C; Zeng J; Hao W; Zhang X; Xu X; Yu C; Deng CX; Chen Q
Theranostics; 2021; 11(4):1672-1689. PubMed ID: 33408774
[No Abstract] [Full Text] [Related]
4. Tumor Priming by smo Inhibition Enhances Antibody Delivery and Efficacy in a pancreatic Ductal Adenocarcinoma Model.
Wang J; Chan DKW; Sen A; Ma WW; Straubinger RM
Mol Cancer Ther; 2019 Nov; 18(11):2074-2084. PubMed ID: 31363010
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5. TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Zhu R; Gires O; Zhu L; Liu J; Li J; Yang H; Ju G; Huang J; Ge W; Chen Y; Lu Z; Wang H
Nat Commun; 2019 Jun; 10(1):2863. PubMed ID: 31253779
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6. Genomic testing, tumor microenvironment and targeted therapy of Hedgehog-related human cancers.
Katoh M
Clin Sci (Lond); 2019 Apr; 133(8):953-970. PubMed ID: 31036756
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7. The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer.
Jia Y; Gu D; Wan J; Yu B; Zhang X; Chiorean EG; Wang Y; Xie J
Oncogene; 2019 Mar; 38(10):1764-1777. PubMed ID: 30382189
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8. Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Song L; Chen X; Wang P; Gao S; Qu C; Liu L
Acta Biochim Biophys Sin (Shanghai); 2018 Jun; 50(6):586-596. PubMed ID: 29697746
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9. The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
Skoda AM; Simovic D; Karin V; Kardum V; Vranic S; Serman L
Bosn J Basic Med Sci; 2018 Feb; 18(1):8-20. PubMed ID: 29274272
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10. Predictors of Response and Survival in Locally Advanced Adenocarcinoma of the Pancreas Following Neoadjuvant GTX with or Without Radiation Therapy.
Sherman WH; Hecht E; Leung D; Chu K
Oncologist; 2018 Jan; 23(1):4-e10. PubMed ID: 29212734
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11. GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment.
Zhou Q; Zhou Y; Liu X; Shen Y
Sci Rep; 2017 Oct; 7(1):13379. PubMed ID: 29042665
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12. Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating pancreatic cancer.
Kumar V; Chaudhary AK; Dong Y; Zhong HA; Mondal G; Lin F; Kumar V; Mahato RI
Sci Rep; 2017 May; 7(1):1665. PubMed ID: 28490735
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13. Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.
Miyazaki Y; Matsubara S; Ding Q; Tsukasa K; Yoshimitsu M; Kosai K; Takao S
Mol Cancer; 2016 Jun; 15(1):49. PubMed ID: 27349387
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14. DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with smoothened inhibitor resistance.
Gruber W; Hutzinger M; Elmer DP; Parigger T; Sternberg C; Cegielkowski L; Zaja M; Leban J; Michel S; Hamm S; Vitt D; Aberger F
Oncotarget; 2016 Feb; 7(6):7134-48. PubMed ID: 26784250
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15. Reduced proliferation and increased apoptosis of the SGC‑7901 gastric cancer cell line on exposure to GDC‑0449.
Wu C; Cheng J; Hu S; Deng R; Muangu YW; Shi L; Wu K; Zhang P; Chang W; Wang G; Tao K
Mol Med Rep; 2016 Feb; 13(2):1434-40. PubMed ID: 26676867
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16. Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic pancreatic cancer.
Catenacci DV; Junttila MR; Karrison T; Bahary N; Horiba MN; Nattam SR; Marsh R; Wallace J; Kozloff M; Rajdev L; Cohen D; Wade J; Sleckman B; Lenz HJ; Stiff P; Kumar P; Xu P; Henderson L; Takebe N; Salgia R; Wang X; Stadler WM; de Sauvage FJ; Kindler HL
J Clin Oncol; 2015 Dec; 33(36):4284-92. PubMed ID: 26527777
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17. Sonidegib: First Global Approval.
Burness CB
Drugs; 2015 Sep; 75(13):1559-66. PubMed ID: 26323341
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18. Ormeloxifene suppresses desmoplasia and enhances sensitivity of gemcitabine in pancreatic cancer.
Khan S; Ebeling MC; Chauhan N; Thompson PA; Gara RK; Ganju A; Yallapu MM; Behrman SW; Zhao H; Zafar N; Singh MM; Jaggi M; Chauhan SC
Cancer Res; 2015 Jun; 75(11):2292-304. PubMed ID: 25840985
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19. Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway.
Qin Y; Ma Z; Dang X; Li W; Ma Q
Mol Med Rep; 2014 Nov; 10(5):2563-7. PubMed ID: 25190613
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20. Standard retrograde pancreatosplenectomy versus radical antegrade modular pancreatosplenectomy for body and tail pancreatic adenocarcinoma.
Latorre M; Ziparo V; Nigri G; Balducci G; Cavallini M; Ramacciato G
Am Surg; 2013 Nov; 79(11):1154-8. PubMed ID: 24165249
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