BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Pancreatic cancer AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS AND Treatment
26 results:

  • 1. DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas.
    Bildik G; Gray JP; Mao W; Yang H; Ozyurt R; Orellana VR; De Wever O; Carey MS; Bast RC; Lu Z
    Autophagy; 2024 Mar; 20(3):675-691. PubMed ID: 38169324
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Cost-Effectiveness Analysis of Screening for pancreatic cancer Among High-Risk Populations.
    Peters MLB; Eckel A; Seguin CL; Davidi B; Howard DH; Knudsen AB; Pandharipande PV
    JCO Oncol Pract; 2024 Feb; 20(2):278-290. PubMed ID: 38086003
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Clinical application of comprehensive genomic profiling panel to thoracic malignancies: A single-center retrospective study.
    Kunimasa K; Sugimoto N; Kawamura T; Yamasaki T; Honma K; Nagata S; Kukita Y; Fujisawa F; Inoue T; Yamaguchi Y; Kitasaka M; Wakamatsu T; Yamai T; Yamamoto S; Hayashi T; Inoue T; Tamiya M; Imamura F; Nishimura K; Nishino K
    Thorac Cancer; 2022 Nov; 13(21):2970-2977. PubMed ID: 36100256
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Cell-Free Tumor DNA Dominant Clone Allele Frequency Is Associated With Poor Outcomes in Advanced Biliary cancers Treated With Platinum-Based Chemotherapy.
    Uson Junior PLS; Majeed U; Yin J; Botrus G; Sonbol MB; Ahn DH; Starr JS; Jones JC; Babiker H; Inabinett SR; Wylie N; Boyle AWR; Bekaii-Saab TS; Gores GJ; Smoot R; Barrett M; Nagalo B; Meurice N; Elliott N; Petit J; Zhou Y; Arora M; Dumbauld C; Barro O; Baker A; Bogenberger J; Buetow K; Mansfield A; Mody K; Borad MJ
    JCO Precis Oncol; 2022 Jun; 6(1):e2100274. PubMed ID: 35666960
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. pancreatic cancer with Mutation in BRCA1/2, MLH1, and APC Genes: Phenotype Correlation and Detection of a Novel Germline BRCA2 Mutation.
    Vietri MT; D'Elia G; Caliendo G; Albanese L; Signoriello G; Napoli C; Molinari AM
    Genes (Basel); 2022 Feb; 13(2):. PubMed ID: 35205366
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.
    Pandey A; Stawiski EW; Durinck S; Gowda H; Goldstein LD; Barbhuiya MA; Schröder MS; Sreenivasamurthy SK; Kim SW; Phalke S; Suryamohan K; Lee K; Chakraborty P; Kode V; Shi X; Chatterjee A; Datta K; Khan AA; Subbannayya T; Wang J; Chaudhuri S; Gupta S; Shrivastav BR; Jaiswal BS; Poojary SS; Bhunia S; Garcia P; Bizama C; Rosa L; Kwon W; Kim H; Han Y; Yadav TD; Ramprasad VL; Chaudhuri A; Modrusan Z; Roa JC; Tiwari PK; Jang JY; Seshagiri S
    Nat Commun; 2020 Aug; 11(1):4225. PubMed ID: 32839463
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carriers of homologous recombination repair genes mutation in response or stable after olaparib treatment.
    Fumet JD; Limagne E; Thibaudin M; Truntzer C; Bertaut A; Rederstorff E; Ghiringhelli F
    BMC Cancer; 2020 Aug; 20(1):748. PubMed ID: 32778095
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The Genomic Landscape of
    Schoenfeld AJ; Bandlamudi C; Lavery JA; Montecalvo J; Namakydoust A; Rizvi H; Egger J; Concepcion CP; Paul S; Arcila ME; Daneshbod Y; Chang J; Sauter JL; Beras A; Ladanyi M; Jacks T; Rudin CM; Taylor BS; Donoghue MTA; Heller G; Hellmann MD; Rekhtman N; Riely GJ
    Clin Cancer Res; 2020 Nov; 26(21):5701-5708. PubMed ID: 32709715
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. [Molecular predictors for the course of disease and individualized therapy in pancreatic cancer].
    Damanakis AI; Gebauer F; Bruns CJ
    Chirurg; 2020 Aug; 91(8):642-649. PubMed ID: 32405728
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Characterization of novel genetic alterations in salivary gland secretory carcinoma.
    Na K; Hernandez-Prera JC; Lim JY; Woo HY; Yoon SO
    Mod Pathol; 2020 Apr; 33(4):541-550. PubMed ID: 31822803
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. lkb1 obliterates Snail stability and inhibits pancreatic cancer metastasis in response to metformin treatment.
    Song L; Guo J; Chang R; Peng X; Li J; Xu X; Zhan X; Zhan L
    Cancer Sci; 2018 May; 109(5):1382-1392. PubMed ID: 29601127
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Chemoprevention in Patients with Peutz-Jeghers Syndrome: Lessons Learned.
    de Brabander J; Eskens FALM; Korsse SE; Dekker E; Dewint P; van Leerdam ME; van Eeden S; Klümpen HJ
    Oncologist; 2018 Apr; 23(4):399-e33. PubMed ID: 29371475
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Management of pancreaticojejunal strictures after pancreaticoduodenectomy: clinical experience and review of literature.
    Ghazanfar MA; Soonawalla Z; Silva MA; Reddy S
    ANZ J Surg; 2018 Jun; 88(6):626-629. PubMed ID: 28653509
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Gastrointestinal diseases and their oro-dental manifestations: Part 4: Peutz-Jeghers syndrome.
    Korsse SE; van Leerdam ME; Dekker E
    Br Dent J; 2017 Feb; 222(3):214-217. PubMed ID: 28184053
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Widely metastatic atypical pituitary adenoma with mTOR pathway stk11(F298L) mutation treated with everolimus therapy.
    Donovan LE; Arnal AV; Wang SH; Odia Y
    CNS Oncol; 2016 Oct; 5(4):203-9. PubMed ID: 27615706
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of lkb1 and activation of AMPK in PDACs.
    Cheng X; Kim JY; Ghafoory S; Duvaci T; Rafiee R; Theobald J; Alborzinia H; Holenya P; Fredebohm J; Merz KH; Mehrabi A; Hafezi M; Saffari A; Eisenbrand G; Hoheisel JD; Wölfl S
    Mol Oncol; 2016 Jun; 10(6):806-24. PubMed ID: 26887594
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Metformin and pancreatic cancer: Is there a role?
    De Souza A; Khawaja KI; Masud F; Saif MW
    Cancer Chemother Pharmacol; 2016 Feb; 77(2):235-42. PubMed ID: 26740120
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Molecular landscape of pancreatic cancer: implications for current clinical trials.
    Heestand GM; Kurzrock R
    Oncotarget; 2015 Mar; 6(7):4553-61. PubMed ID: 25714017
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Metformin and cancer.
    Vallianou NG; Evangelopoulos A; Kazazis C
    Rev Diabet Stud; 2013; 10(4):228-35. PubMed ID: 24841876
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Contribution of CXCR4 and SMAD4 in predicting disease progression pattern and benefit from adjuvant chemotherapy in resected pancreatic adenocarcinoma.
    Bachet JB; Maréchal R; Demetter P; Bonnetain F; Couvelard A; Svrcek M; Bardier-Dupas A; Hammel P; Sauvanet A; Louvet C; Paye F; Rougier P; Penna C; Vaillant JC; André T; Closset J; Salmon I; Emile JF; Van Laethem JL
    Ann Oncol; 2012 Sep; 23(9):2327-2335. PubMed ID: 22377565
    [TBL] [Abstract] [Full Text] [Related]  


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