Terms: = Pancreatic cancer AND TFEB, TCFEB, 7942, ENSG00000112561, P19484, AlphaTFEB
20 results:
1. The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs.
Yang S; Ting CY; Lilly MA
Mol Cell; 2024 Feb; 84(4):727-743.e8. PubMed ID: 38325378
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2. DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas.
Bildik G; Gray JP; Mao W; Yang H; Ozyurt R; Orellana VR; De Wever O; Carey MS; Bast RC; Lu Z
Autophagy; 2024 Mar; 20(3):675-691. PubMed ID: 38169324
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3. LncRNA XXYLT1-AS2 promotes tumor progression via autophagy inhibition through ubiquitinated degradation of tfeb in hepatocellular carcinoma.
Li X; Wu Y; Wang P; Li Y; Gu J; Zhang Y; Yan S; Hu P
Clin Transl Oncol; 2024 Mar; 26(3):698-708. PubMed ID: 37540409
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4. A new glance at autophagolysosomal-dependent or -independent function of transcriptional factor EB in human cancer.
Wang T; Qin Y; Ye Z; Jing DS; Fan GX; Liu MQ; Zhuo QF; Ji SR; Chen XM; Yu XJ; Xu XW; Li Z
Acta Pharmacol Sin; 2023 Aug; 44(8):1536-1548. PubMed ID: 37012494
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5. The Expression of Autophagy-Associated Genes Represents a Valid Footprint for Aggressive pancreatic Neuroendocrine Neoplasms.
Matrood S; Melms LE; Bartsch DK; Di Fazio P
Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36835048
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6. EWI2 and its relatives in Tetraspanin-enriched membrane domains regulate malignancy.
Ding Y; Chen J; Li S; Wren JD; Bajpai AK; Wang J; Tanaka T; Rice HC; Hays FA; Lu L; Zhang XA
Oncogene; 2023 Mar; 42(12):861-868. PubMed ID: 36788350
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7. Risk factors for biliary stent infections in malignant biliary obstruction secondary to unresectable malignancies.
Petit S; Puyade M; Pichon M; Wangermez M; Velasco S; Roblot F; Isambert N; Evrard C; Rammaert B
Support Care Cancer; 2022 Aug; 30(8):6937-6946. PubMed ID: 35543817
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8. Multifaceted activities of transcription factor EB in cancer onset and progression.
Astanina E; Bussolino F; Doronzo G
Mol Oncol; 2021 Feb; 15(2):327-346. PubMed ID: 33252196
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9. tfeb-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells.
He R; Wang M; Zhao C; Shen M; Yu Y; He L; Zhao Y; Chen H; Shi X; Zhou M; Pan S; Liu Y; Guo X; Li X; Qin R
J Exp Clin Cancer Res; 2019 Aug; 38(1):340. PubMed ID: 31387632
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10. METTL3 and ALKBH5 oppositely regulate m
Song H; Feng X; Zhang H; Luo Y; Huang J; Lin M; Jin J; Ding X; Wu S; Huang H; Yu T; Zhang M; Hong H; Yao S; Zhao Y; Zhang Z
Autophagy; 2019 Aug; 15(8):1419-1437. PubMed ID: 30870073
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11. Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in β-cells.
Ji J; Petropavlovskaia M; Khatchadourian A; Patapas J; Makhlin J; Rosenberg L; Maysinger D
J Cell Mol Med; 2019 Apr; 23(4):2890-2900. PubMed ID: 30710421
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12. Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting tfeb.
He R; Shi X; Zhou M; Zhao Y; Pan S; Zhao C; Guo X; Wang M; Li X; Qin R
Toxicol Appl Pharmacol; 2018 Oct; 356():159-171. PubMed ID: 30086361
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13. Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.
Lundquist MR; Goncalves MD; Loughran RM; Possik E; Vijayaraghavan T; Yang A; Pauli C; Ravi A; Verma A; Yang Z; Johnson JL; Wong JCY; Ma Y; Hwang KS; Weinkove D; Divecha N; Asara JM; Elemento O; Rubin MA; Kimmelman AC; Pause A; Cantley LC; Emerling BM
Mol Cell; 2018 May; 70(3):531-544.e9. PubMed ID: 29727621
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14. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.
Sakamaki JI; Wilkinson S; Hahn M; Tasdemir N; O'Prey J; Clark W; Hedley A; Nixon C; Long JS; New M; Van Acker T; Tooze SA; Lowe SW; Dikic I; Ryan KM
Mol Cell; 2017 May; 66(4):517-532.e9. PubMed ID: 28525743
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15. Autophagy is required for PDAC glutamine metabolism.
Seo JW; Choi J; Lee SY; Sung S; Yoo HJ; Kang MJ; Cheong H; Son J
Sci Rep; 2016 Nov; 6():37594. PubMed ID: 27892481
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16. Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential.
Kwon JJ; Willy JA; Quirin KA; Wek RC; Korc M; Yin XM; Kota J
Oncotarget; 2016 Nov; 7(44):71635-71650. PubMed ID: 27626694
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17. Role of tfeb-driven autophagy regulation in pancreatic cancer treatment.
Klein K; Werner K; Teske C; Schenk M; Giese T; Weitz J; Welsch T
Int J Oncol; 2016 Jul; 49(1):164-72. PubMed ID: 27175909
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18. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Perera RM; Stoykova S; Nicolay BN; Ross KN; Fitamant J; Boukhali M; Lengrand J; Deshpande V; Selig MK; Ferrone CR; Settleman J; Stephanopoulos G; Dyson NJ; Zoncu R; Ramaswamy S; Haas W; Bardeesy N
Nature; 2015 Aug; 524(7565):361-5. PubMed ID: 26168401
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19. Glycogen synthase kinase-3 (GSK3) inhibition induces prosurvival autophagic signals in human pancreatic cancer cells.
Marchand B; Arsenault D; Raymond-Fleury A; Boisvert FM; Boucher MJ
J Biol Chem; 2015 Feb; 290(9):5592-605. PubMed ID: 25561726
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20. Quantitative glycoproteomics analysis reveals changes in N-glycosylation level associated with pancreatic ductal adenocarcinoma.
Pan S; Chen R; Tamura Y; Crispin DA; Lai LA; May DH; McIntosh MW; Goodlett DR; Brentnall TA
J Proteome Res; 2014 Mar; 13(3):1293-306. PubMed ID: 24471499
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