Terms: = Pancreatic cancer AND TGFBR2, AAT3, 7048, ENSG00000163513, P37173, TGFbeta-RII, RIIC, TAAD2, FAA3, TGFR-2, MFS2, HNPCC6
45 results:
1. Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma.
Yang X; Lian B; Zhang N; Long J; Li Y; Xue J; Chen X; Wang Y; Wang Y; Xun Z; Piao M; Zhu C; Wang S; Sun H; Song Z; Lu L; Dong X; Wang A; Liu W; Pan J; Hou X; Guan M; Huo L; Shi J; Zhang H; Zhou J; Lu Z; Mao Y; Sang X; Wu L; Yang X; Wang K; Zhao H
BMC Med; 2024 Jan; 22(1):42. PubMed ID: 38281914
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2. Dysregulation of the circ_0087502/miR-1179/tgfbr2 pathway supports gemcitabine resistance in pancreatic cancer.
Chen M; Liu X; Lu J; Teng H; Yu C; Liu Y; Zheng Y
Cancer Biol Ther; 2023 Dec; 24(1):2258566. PubMed ID: 37844011
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3. ST6GALNAC4 promotes hepatocellular carcinogenesis by inducing abnormal glycosylation.
Man D; Jiang Y; Zhang D; Wu J; Ding B; Liu H; Xu G; Lu J; Ru J; Tong R; Zheng S; Chen D; Wu J
J Transl Med; 2023 Jun; 21(1):420. PubMed ID: 37381011
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4. USP33 promotes pancreatic cancer malignant phenotype through the regulation of tgfbr2/TGFβ signaling pathway.
Liu X; Xu J; Shen B; Xu J; Jiang J
Cell Death Dis; 2023 Jun; 14(6):362. PubMed ID: 37322017
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5. Neutrophil-mediated fibroblast-tumor cell il-6/stat-3 signaling underlies the association between neutrophil-to-lymphocyte ratio dynamics and chemotherapy response in localized pancreatic cancer: A hybrid clinical-preclinical study.
de Castro Silva I; Bianchi A; Deshpande NU; Sharma P; Mehra S; Garrido VT; Saigh SJ; England J; Hosein PJ; Kwon D; Merchant NB; Datta J
Elife; 2022 Sep; 11():. PubMed ID: 36107485
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6. Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary cancer in Mice.
Nagao M; Fukuda A; Omatsu M; Namikawa M; Sono M; Fukunaga Y; Masuda T; Araki O; Yoshikawa T; Ogawa S; Masuo K; Goto N; Hiramatsu Y; Muta Y; Tsuda M; Maruno T; Nakanishi Y; Taketo MM; Ferrer J; Tsuruyama T; Nakanuma Y; Taura K; Uemoto S; Seno H
Cancer Res; 2022 May; 82(9):1803-1817. PubMed ID: 35247892
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7. The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification.
Yang Y; Ding Y; Gong Y; Zhao S; Li M; Li X; Song G; Zhai B; Liu J; Shao Y; Zhu L; Pang J; Ma Y; Ou Q; Wu X; Zhang Z
BMC Cancer; 2022 Feb; 22(1):186. PubMed ID: 35180847
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8. Targeting Tumor-Stromal IL6/STAT3 Signaling through IL1 Receptor Inhibition in pancreatic cancer.
Dosch AR; Singh S; Dai X; Mehra S; Silva IC; Bianchi A; Srinivasan S; Gao Z; Ban Y; Chen X; Banerjee S; Nagathihalli NS; Datta J; Merchant NB
Mol Cancer Ther; 2021 Nov; 20(11):2280-2290. PubMed ID: 34518296
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9. Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in pancreatic Ductal Adenocarcinoma.
Willobee BA; Gaidarski AA; Dosch AR; Castellanos JA; Dai X; Mehra S; Messaggio F; Srinivasan S; VanSaun MN; Nagathihalli NS; Merchant NB
Mol Cancer Ther; 2021 Jul; 20(7):1246-1256. PubMed ID: 34001634
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10. Deep Targeted Sequencing and Its Potential Implication for cancer Therapy in Chinese Patients with Gastric Adenocarcinoma.
Yu P; Wang Y; Yu Y; Wang A; Huang L; Zhang Y; Liu W; Wu H; Yao M; Du YA; Cheng X
Oncologist; 2021 May; 26(5):e756-e768. PubMed ID: 33511732
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11. Blocking VCAM-1 inhibits pancreatic tumour progression and cancer-associated thrombosis/thromboembolism.
Sano M; Takahashi R; Ijichi H; Ishigaki K; Yamada T; Miyabayashi K; Kimura G; Mizuno S; Kato H; Fujiwara H; Nakatsuka T; Tanaka Y; Kim J; Masugi Y; Morishita Y; Tanaka M; Ushiku T; Nakai Y; Tateishi K; Ishii Y; Isayama H; Moses HL; Koike K
Gut; 2021 Sep; 70(9):1713-1723. PubMed ID: 33087490
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12. Establishment and characterization of NCC-mfs2-C1: a novel patient-derived cancer cell line of myxofibrosarcoma.
Noguchi R; Yoshimatsu Y; Ono T; Sei A; Hirabayashi K; Ozawa I; Kikuta K; Kondo T
Hum Cell; 2021 Jan; 34(1):246-253. PubMed ID: 32870449
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13. Genomic characterization of malignant progression in neoplastic pancreatic cysts.
Noë M; Niknafs N; Fischer CG; Hackeng WM; Beleva Guthrie V; Hosoda W; Debeljak M; Papp E; Adleff V; White JR; Luchini C; Pea A; Scarpa A; Butturini G; Zamboni G; Castelli P; Hong SM; Yachida S; Hiraoka N; Gill AJ; Samra JS; Offerhaus GJA; Hoorens A; Verheij J; Jansen C; Adsay NV; Jiang W; Winter J; Albores-Saavedra J; Terris B; Thompson ED; Roberts NJ; Hruban RH; Karchin R; Scharpf RB; Brosens LAA; Velculescu VE; Wood LD
Nat Commun; 2020 Aug; 11(1):4085. PubMed ID: 32796935
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14. Pattern of Invasion in Human pancreatic cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome.
Huang W; Navarro-Serer B; Jeong YJ; Chianchiano P; Xia L; Luchini C; Veronese N; Dowiak C; Ng T; Trujillo MA; Huang B; Pflüger MJ; Macgregor-Das AM; Lionheart G; Jones D; Fujikura K; Nguyen-Ngoc KV; Neumann NM; Groot VP; Hasanain A; van Oosten AF; Fischer SE; Gallinger S; Singhi AD; Zureikat AH; Brand RE; Gaida MM; Heinrich S; Burkhart RA; He J; Wolfgang CL; Goggins MG; Thompson ED; Roberts NJ; Ewald AJ; Wood LD
Cancer Res; 2020 Jul; 80(13):2804-2817. PubMed ID: 32376602
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15. Combined Src/EGFR Inhibition Targets STAT3 Signaling and Induces Stromal Remodeling to Improve Survival in pancreatic cancer.
Dosch AR; Dai X; Reyzer ML; Mehra S; Srinivasan S; Willobee BA; Kwon D; Kashikar N; Caprioli R; Merchant NB; Nagathihalli NS
Mol Cancer Res; 2020 Apr; 18(4):623-631. PubMed ID: 31949002
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16. Ganglioside GM2, highly expressed in the MIA PaCa-2 pancreatic ductal adenocarcinoma cell line, is correlated with growth, invasion, and advanced stage.
Sasaki N; Hirabayashi K; Michishita M; Takahashi K; Hasegawa F; Gomi F; Itakura Y; Nakamura N; Toyoda M; Ishiwata T
Sci Rep; 2019 Dec; 9(1):19369. PubMed ID: 31852956
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17. A super-enhancer controls TGF- β signaling in pancreatic cancer through downregulation of tgfbr2.
Zhu X; Zhang T; Zhang Y; Chen H; Shen J; Jin X; Wei J; Zhang E; Xiao M; Fan Y; Mao R; Zhou G
Cell Signal; 2020 Feb; 66():109470. PubMed ID: 31730895
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18. Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis.
Matsuura T; Maru Y; Izumiya M; Hoshi D; Kato S; Ochiai M; Hori M; Yamamoto S; Tatsuno K; Imai T; Aburatani H; Nakajima A; Hippo Y
Carcinogenesis; 2020 Jun; 41(4):490-501. PubMed ID: 31233118
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19. Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in pancreatic cancer.
Totiger TM; Srinivasan S; Jala VR; Lamichhane P; Dosch AR; Gaidarski AA; Joshi C; Rangappa S; Castellanos J; Vemula PK; Chen X; Kwon D; Kashikar N; VanSaun M; Merchant NB; Nagathihalli NS
Mol Cancer Ther; 2019 Feb; 18(2):301-311. PubMed ID: 30404927
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20. Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in pancreatic cancer.
Nagathihalli NS; Castellanos JA; Lamichhane P; Messaggio F; Shi C; Dai X; Rai P; Chen X; VanSaun MN; Merchant NB
Cancer Res; 2018 Nov; 78(21):6235-6246. PubMed ID: 30154150
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