Terms: = Pancreatic cancer AND uPA
109 results:
1. Circulating tumor DNA in unresectable pancreatic cancer is a strong predictor of first-line treatment efficacy: The KRASCIPANC prospective study.
Evrard C; Ingrand P; Rochelle T; Martel M; Tachon G; Flores N; Randrian V; Ferru A; Haineaux PA; Goujon JM; Karayan-Tapon L; Tougeron D
Dig Liver Dis; 2023 Nov; 55(11):1562-1572. PubMed ID: 37308396
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2. Urokinase plasminogen activator induces epithelial-mesenchymal and metastasis of pancreatic cancer through plasmin/MMP14/TGF-β axis, which is inhibited by 4-acetyl-antroquinonol B treatment.
Wu CZ; Chu YC; Lai SW; Hsieh MS; Yadav VK; Fong IH; Deng L; Huang CC; Tzeng YM; Yeh CT; Chen JS
Phytomedicine; 2022 Jun; 100():154062. PubMed ID: 35366491
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3. The Urokinase Plasminogen Activation System in pancreatic cancer: Prospective Diagnostic and Therapeutic Targets.
Kumar AA; Buckley BJ; Ranson M
Biomolecules; 2022 Jan; 12(2):. PubMed ID: 35204653
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4. STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway.
Conde de la Rosa L; Garcia-Ruiz C; Vallejo C; Baulies A; Nuñez S; Monte MJ; Marin JJG; Baila-Rueda L; Cenarro A; Civeira F; Fuster J; Garcia-Valdecasas JC; Ferrer J; Karin M; Ribas V; Fernandez-Checa JC
J Hepatol; 2021 Jun; 74(6):1429-1441. PubMed ID: 33515644
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5. A Notch-Dependent Inflammatory Feedback Circuit between Macrophages and cancer Cells Regulates pancreatic cancer Metastasis.
Geng Y; Fan J; Chen L; Zhang C; Qu C; Qian L; Chen K; Meng Z; Chen Z; Wang P
Cancer Res; 2021 Jan; 81(1):64-76. PubMed ID: 33172931
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6. Multiplex quantitative analysis of stroma-mediated cancer cell invasion, matrix remodeling, and drug response in a 3D co-culture model of pancreatic tumor spheroids and stellate cells.
Hwang HJ; Oh MS; Lee DW; Kuh HJ
J Exp Clin Cancer Res; 2019 Jun; 38(1):258. PubMed ID: 31200779
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7. Curcumin attenuates hyperglycemia-driven EGF-induced invasive and migratory abilities of pancreatic cancer via suppression of the ERK and AKT pathways.
Li W; Wang Z; Xiao X; Han L; Wu Z; Ma Q; Cao L
Oncol Rep; 2019 Jan; 41(1):650-658. PubMed ID: 30542713
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8. 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in cancer.
Buckley BJ; Aboelela A; Minaei E; Jiang LX; Xu Z; Ali U; Fildes K; Cheung CY; Cook SM; Johnson DC; Bachovchin DA; Cook GM; Apte M; Huang M; Ranson M; Kelso MJ
J Med Chem; 2018 Sep; 61(18):8299-8320. PubMed ID: 30130401
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9. Early detection of pancreatic cancers in liquid biopsies by ultrasensitive fluorescence nanobiosensors.
Kalubowilage M; Covarrubias-Zambrano O; Malalasekera AP; Wendel SO; Wang H; Yapa AS; Chlebanowski L; Toledo Y; Ortega R; Janik KE; Shrestha TB; Culbertson CT; Kasi A; Williamson S; Troyer DL; Bossmann SH
Nanomedicine; 2018 Aug; 14(6):1823-1832. PubMed ID: 29782949
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10. Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (upa) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs).
Wang L; Zhang Y; Wang W; Zhu Y; Chen Y; Tian B
PLoS One; 2017; 12(8):e0184110. PubMed ID: 28854261
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11. [Stem cell factor enhances invasive ability of BxPC-3 cells via hypoxia-inducible factor 1α (HIF-1α)].
Zhang M; Guo K; Li Q; Wang Y; Zhang L; He T; Wan B; Wang X
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2017 Jul; 33(7):903-908. PubMed ID: 28712397
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12. SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer.
Harris NLE; Vennin C; Conway JRW; Vine KL; Pinese M; Cowley MJ; Shearer RF; Lucas MC; Herrmann D; Allam AH; Pajic M; Morton JP; ; Biankin AV; Ranson M; Timpson P; Saunders DN
Oncogene; 2017 Jul; 36(30):4288-4298. PubMed ID: 28346421
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13. The Transient Receptor Potential Melastatin 7 Channel Regulates pancreatic cancer Cell Invasion through the Hsp90α/upa/MMP2 pathway.
Rybarczyk P; Vanlaeys A; Brassart B; Dhennin-Duthille I; Chatelain D; Sevestre H; Ouadid-Ahidouch H; Gautier M
Neoplasia; 2017 Apr; 19(4):288-300. PubMed ID: 28284058
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14. Can MDCT or EUS features predict the histopathological grading scheme of pancreatic neuroendocrine neoplasms?
Zhu H; Ying L; Tang W; Yang X; Sun B
Radiol Med; 2017 May; 122(5):319-326. PubMed ID: 28176217
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15. Association between high levels of Notch3 expression and high invasion and poor overall survival rates in pancreatic ductal adenocarcinoma.
Zhou JX; Zhou L; Li QJ; Feng W; Wang PM; Li EF; Gong WJ; Kou MW; Gou WT; Yang YL
Oncol Rep; 2016 Nov; 36(5):2893-2901. PubMed ID: 27633819
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16. Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor.
Drebert Z; MacAskill M; Doughty-Shenton D; De Bosscher K; Bracke M; Hadoke PWF; Beck IM
Vascul Pharmacol; 2017 Feb; 89():19-30. PubMed ID: 27717848
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17. Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.
Cao L; Chen X; Xiao X; Ma Q; Li W
Int J Oncol; 2016 Aug; 49(2):735-43. PubMed ID: 27278736
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18. Identification of pancreatic tumors in vivo with ligand-targeted, pH responsive mesoporous silica nanoparticles by multispectral optoacoustic tomography.
Gurka MK; Pender D; Chuong P; Fouts BL; Sobelov A; McNally MW; Mezera M; Woo SY; McNally LR
J Control Release; 2016 Jun; 231():60-7. PubMed ID: 26763377
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19. Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway.
Li W; Cao L; Chen X; Lei J; Ma Q
Oncol Rep; 2016 Mar; 35(3):1718-26. PubMed ID: 26707376
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20. Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer.
Li W; Ma Z; Ma J; Li X; Xu Q; Duan W; Chen X; Lv Y; Zhou S; Wu E; Ma Q; Huo X
Oncotarget; 2015 Oct; 6(31):31119-33. PubMed ID: 26439801
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