Terms: = Prostate cancer AND EP300, ENSG00000100393, 2033, RP1-85F18_1, p300 AND Treatment
69 results:
1. Discovery of CBPD-409 as a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the treatment of Advanced prostate cancer.
Chen Z; Wang M; Wu D; Zhao L; Metwally H; Jiang W; Wang Y; Bai L; McEachern D; Luo J; Wang M; Li Q; Matvekas A; Wen B; Sun D; Chinnaiyan AM; Wang S
J Med Chem; 2024 Apr; 67(7):5351-5372. PubMed ID: 38530938
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2. CBP/p300 Degrader: A Promising Therapeutic Strategy for treatment of prostate cancer and Beyond.
Hu J; Xu Y
J Med Chem; 2024 Apr; 67(7):5272-5274. PubMed ID: 38517344
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3. Discovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression.
Chen Z; Wang M; Wu D; Bai L; Xu T; Metwally H; Wang Y; McEachern D; Zhao L; Li R; Takyi-Williams J; Wang M; Wang L; Li Q; Wen B; Sun D; Wang S
J Med Chem; 2024 Apr; 67(7):5275-5304. PubMed ID: 38477974
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4. Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer.
Helminen L; Huttunen J; Tulonen M; Aaltonen N; Niskanen EA; Palvimo JJ; Paakinaho V
Nucleic Acids Res; 2024 Jan; 52(2):625-642. PubMed ID: 38015476
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5. Androgen Receptor Variants Confer Castration Resistance in prostate cancer by Counteracting Antiandrogen-Induced Ferroptosis.
Sun R; Yan B; Li H; Ding D; Wang L; Pang J; Ye D; Huang H
Cancer Res; 2023 Oct; 83(19):3192-3204. PubMed ID: 37527336
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6. YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
Chen S; Lu K; Hou Y; You Z; Shu C; Wei X; Wu T; Shi N; Zhang G; Wu J; Chen S; Zhang L; Li W; Zhang D; Ju S; Chen M; Xu B
J Immunother Cancer; 2023 Apr; 11(4):. PubMed ID: 37094986
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7. Radiation Therapy Expenditures Through the First 8 Performance Periods of the Oncology Care Model at a Statewide Multispecialty Health System.
De B; Andres G; Bates C; Staren E; Kutscher E; Brooks DJ; Thaker GH; Buscema J; Gin R; Thaker N
Int J Radiat Oncol Biol Phys; 2023 Jul; 116(3):491-499. PubMed ID: 36427644
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8. Targeting CDCP1 gene transcription coactivated by BRD4 and CBP/p300 in castration-resistant prostate cancer.
Ji D; Shang G; Wei E; Jia Y; Wang C; Zhang Q; Zeng L
Oncogene; 2022 Jun; 41(23):3251-3262. PubMed ID: 35513563
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9. Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress.
Liao Y; Chen CH; Xiao T; de la Peña Avalos B; Dray EV; Cai C; Gao S; Shah N; Zhang Z; Feit A; Xue P; Liu Z; Yang M; Lee JH; Xu H; Li W; Mei S; Pierre RS; Shu S; Fei T; Duarte M; Zhao J; Bradner JE; Polyak K; Kantoff PW; Long H; Balk SP; Liu XS; Brown M; Xu K
Proc Natl Acad Sci U S A; 2022 Jan; 119(3):. PubMed ID: 35031563
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10. Home Se-Cure: A Home Care Service for cancer Patients during the COVID-19 Pandemic.
Buttiron Webber T; Giuliano S; Patrone C; Briata IM; Franconeri M; Marceca F; Magnani M; Paciolla F; Provinciali N; Defferrari C; Clavarezza M; D'Amico M; Gozza A; Boitano M; Alessio-Mazzola M; Cevasco I; DeCensi A
Int J Environ Res Public Health; 2021 Oct; 18(20):. PubMed ID: 34682650
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11. BAZ2A-mediated repression via H3K14ac-marked enhancers promotes prostate cancer stem cells.
Peña-Hernández R; Aprigliano R; Carina Frommel S; Pietrzak K; Steiger S; Roganowicz M; Lerra L; Bizzarro J; Santoro R
EMBO Rep; 2021 Nov; 22(11):e53014. PubMed ID: 34403195
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12. Genetic and epigenetic bases of prostate tumor cell radioresistance.
Kutilin D
Klin Onkol; 2021; 34(3):220-234. PubMed ID: 34362257
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13. Genetic and epigenetic bases of prostate tumor cell radioresistance.
Kutilin Denis
Ceska Gynekol; 2021; 86(3):220-234. PubMed ID: 34192880
[TBL] [Abstract] [Full Text] [Related]
14. Synthesis and Biological Evaluation of Spirocyclic Chromane Derivatives as a Potential treatment of prostate cancer.
Feng L; Yu S; Wang H; Yang S; Li X; Dai H; Zhao L; Jiang C; Wang Y
Molecules; 2021 May; 26(11):. PubMed ID: 34070610
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15. A noncanonical AR addiction drives enzalutamide resistance in prostate cancer.
He Y; Wei T; Ye Z; Orme JJ; Lin D; Sheng H; Fazli L; Jeffrey Karnes R; Jimenez R; Wang L; Wang L; Gleave ME; Wang Y; Shi L; Huang H
Nat Commun; 2021 Mar; 12(1):1521. PubMed ID: 33750801
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16. MYC-Mediated Ribosomal Gene Expression Sensitizes Enzalutamide-resistant prostate cancer Cells to ep300/CREBBP Inhibitors.
Furlan T; Kirchmair A; Sampson N; Puhr M; Gruber M; Trajanoski Z; Santer FR; Parson W; Handle F; Culig Z
Am J Pathol; 2021 Jun; 191(6):1094-1107. PubMed ID: 33705753
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17. Abiraterone Acetate Induces CREB1 Phosphorylation and Enhances the Function of the CBP-p300 Complex, Leading to Resistance in prostate cancer Cells.
Pan W; Zhang Z; Kimball H; Qu F; Berlind K; Stopsack KH; Lee GM; Choueiri TK; Kantoff PW
Clin Cancer Res; 2021 Apr; 27(7):2087-2099. PubMed ID: 33495313
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18. Targeting the p300/CBP Axis in Lethal prostate cancer.
Welti J; Sharp A; Brooks N; Yuan W; McNair C; Chand SN; Pal A; Figueiredo I; Riisnaes R; Gurel B; Rekowski J; Bogdan D; West W; Young B; Raja M; Prosser A; Lane J; Thomson S; Worthington J; Onions S; Shannon J; Paoletta S; Brown R; Smyth D; Harbottle GW; Gil VS; Miranda S; Crespo M; Ferreira A; Pereira R; Tunariu N; Carreira S; Neeb AJ; Ning J; Swain A; Taddei D; ; Schiewer MJ; Knudsen KE; Pegg N; de Bono JS
Cancer Discov; 2021 May; 11(5):1118-1137. PubMed ID: 33431496
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19. Current development of CBP/p300 inhibitors in the last decade.
He ZX; Wei BF; Zhang X; Gong YP; Ma LY; Zhao W
Eur J Med Chem; 2021 Jan; 209():112861. PubMed ID: 33045661
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20. p300-Mediated Acetylation of Histone Demethylase JMJD1A Prevents Its Degradation by Ubiquitin Ligase STUB1 and Enhances Its Activity in prostate cancer.
Xu S; Fan L; Jeon HY; Zhang F; Cui X; Mickle MB; Peng G; Hussain A; Fazli L; Gleave ME; Dong X; Qi J
Cancer Res; 2020 Aug; 80(15):3074-3087. PubMed ID: 32522824
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