BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Prostate cancer AND FH, HLRCC, 2271, ENSG00000091483, MCUL1, MCL, LRCC, P07954 AND Treatment
115 results:

  • 1. The Effect of treatment Intensification on Other-Cause Mortality in Clear-Cell Metastatic Renal Cell Carcinoma Patients.
    Incesu RB; Barletta F; Garcia CC; Scheipner L; Morra S; Baudo A; Assad A; Tian Z; Saad F; Shariat SF; Carmignani L; Longo N; Ahyai S; Chun FKH; Briganti A; Tilki D; Graefen M; Karakiewicz PI
    Clin Genitourin Cancer; 2024 Apr; 22(2):420-425. PubMed ID: 38307818
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Discovery of novel flavonoid-based CDK9 degraders for prostate cancer treatment via a PROTAC strategy.
    Wu T; Zhang Z; Gong G; Du Z; Xu Y; Yu S; Ma F; Zhang X; Wang Y; Chen H; Wu S; Xu X; Qiu Z; Li Z; Wu H; Bian J; Wang J
    Eur J Med Chem; 2023 Nov; 260():115774. PubMed ID: 37672930
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Targeted silencing of the mcl-1 gene using multi-layered dendrimer-based nanoconstructs achieves efficient tumor regression in xenografted mice models.
    Tambe P; Salve R; Choudhary P; Kumar P; Jadhav S; Paknikar KM; Gajbhiye V
    Int J Pharm; 2023 Mar; 634():122659. PubMed ID: 36720446
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Lucanthone, Autophagy Inhibitor, Enhances the Apoptotic Effects of TRAIL through miR-216a-5p-Mediated DR5 Upregulation and DUB3-Mediated mcl-1 Downregulation.
    Yoon JY; Woo SM; Seo SU; Song SR; Lee SG; Kwon TK
    Int J Mol Sci; 2021 Dec; 23(1):. PubMed ID: 35008442
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Evasion of cell death: A contributory factor in prostate cancer development and treatment resistance.
    Campbell KJ; Leung HY
    Cancer Lett; 2021 Nov; 520():213-221. PubMed ID: 34343635
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. PARP and CDK4/6 Inhibitor Combination Therapy Induces Apoptosis and Suppresses Neuroendocrine Differentiation in prostate cancer.
    Wu C; Peng S; Pilié PG; Geng C; Park S; Manyam GC; Lu Y; Yang G; Tang Z; Kondraganti S; Wang D; Hudgens CW; Ledesma DA; Marques-Piubelli ML; Torres-Cabala CA; Curry JL; Troncoso P; Corn PG; Broom BM; Thompson TC
    Mol Cancer Ther; 2021 Sep; 20(9):1680-1691. PubMed ID: 34158347
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. A Potential Role for HUWE1 in Modulating Cisplatin Sensitivity.
    Wenmaekers S; Viergever BJ; Kumar G; Kranenburg O; Black PC; Daugaard M; Meijer RP
    Cells; 2021 May; 10(5):. PubMed ID: 34065298
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. The Role of BCL-2 Proteins in the Development of Castration-resistant prostate cancer and Emerging Therapeutic Strategies.
    Soliman L; De Souza A; Srinivasan P; Danish M; Bertone P; El-Deiry WS; Carneiro BA
    Am J Clin Oncol; 2021 Jul; 44(7):374-382. PubMed ID: 34014842
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. β-elemonic acid inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells through the suppression of JAK2/STAT3/mcl-1 and NF-ĸB signal pathways.
    Bao X; Zhu J; Ren C; Zhao A; Zhang M; Zhu Z; Lu X; Zhang Y; Li X; Sima X; Li J; Zhang Q; Ma B
    Chem Biol Interact; 2021 Jun; 342():109477. PubMed ID: 33878321
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Unexpected hematologic malignancies after prostatectomy: Case report and literature review.
    Karademir B; Kısa E; Özbilen MH; Bildirici Ç; Karabacakoğlu B; Süelözgen T; İlbey YÖ; Küçük Ü; Olgun A
    Urologia; 2021 Nov; 88(4):382-385. PubMed ID: 33579183
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Synthesis and evaluation of a UMI-77-based fluorescent probe for selective detecting mcl-1 protein and imaging in living cancer cells.
    Li J; Hou X; Bai J; Zhou Y; Chen C; Yang X; Fang H
    Bioorg Med Chem; 2021 Jan; 29():115850. PubMed ID: 33229135
    [TBL] [Abstract] [Full Text] [Related]  

  • 12.
    Bai L; Li X; Ma X; Zhao R; Wu D
    Anticancer Res; 2020 Nov; 40(11):6051-6062. PubMed ID: 33109543
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
    Hu C; Xia H; Bai S; Zhao J; Edwards H; Li X; Yang Y; Lyu J; Wang G; Zhan Y; Dong Y; Ge Y
    J Cell Mol Med; 2020 Jul; 24(13):7239-7253. PubMed ID: 32459381
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Eprinomectin, a novel semi-synthetic macrocylic lactone is cytotoxic to PC3 metastatic prostate cancer cells via inducing apoptosis.
    Samy ALPA; Bakthavachalam V; Vudutha M; Vinjamuri S; Chinnapaka S; Munirathinam G
    Toxicol Appl Pharmacol; 2020 Aug; 401():115071. PubMed ID: 32454055
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Bim, Puma and Noxa upregulation by Naftopidil sensitizes ovarian cancer to the BH3-mimetic ABT-737 and the MEK inhibitor Trametinib.
    Florent R; Weiswald LB; Lambert B; Brotin E; Abeilard E; Louis MH; Babin G; Poulain L; N'Diaye M
    Cell Death Dis; 2020 May; 11(5):380. PubMed ID: 32424251
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Ethacrynic acid inhibits STAT3 activity through the modulation of SHP2 and PTP1B tyrosine phosphatases in DU145 prostate carcinoma cells.
    Lee YJ; Song H; Yoon YJ; Park SJ; Kim SY; Cho Han D; Kwon BM
    Biochem Pharmacol; 2020 May; 175():113920. PubMed ID: 32201212
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Arctigenin induces necroptosis through mitochondrial dysfunction with CCN1 upregulation in prostate cancer cells under lactic acidosis.
    Lee YJ; Nam HS; Cho MK; Lee SH
    Mol Cell Biochem; 2020 Apr; 467(1-2):45-56. PubMed ID: 32065351
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Ascleposide, a natural cardenolide, induces anticancer signaling in human castration-resistant prostatic cancer through Na
    Leu WJ; Wang CT; Hsu JL; Chen IS; Chang HS; Guh JH
    Prostate; 2020 Mar; 80(4):305-318. PubMed ID: 31905252
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Molecular mechanism of C-phycocyanin induced apoptosis in LNCaP cells.
    Kaur P; Dhandayuthapani S; Venkatesan T; Gantor M; Rathinavelu A
    Bioorg Med Chem; 2020 Feb; 28(3):115272. PubMed ID: 31883786
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Multifocal Signal Modulation Therapy by Celecoxib: A Strategy for Managing Castration-Resistant prostate cancer.
    Benelli R; Barboro P; Costa D; Astigiano S; Barbieri O; Capaia M; Poggi A; Ferrari N
    Int J Mol Sci; 2019 Dec; 20(23):. PubMed ID: 31816863
    [TBL] [Abstract] [Full Text] [Related]  


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