BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Prostate cancer AND HSP90AA1, ENSG00000080824, 3320, P07900, LAP2, HSPN, HSPCAL4, HSPCAL1, HSPCA, HSPC1, HSP90N, HSP90A, Hsp90, Hsp89, HSP86, FLJ31884 AND Treatment
114 results:

  • 1. Combination of navitoclax (Bcl-2 and Bcl-xL inhibitor) and Debio-0932 (hsp90 inhibitor) suppresses the viability of prostate cancer cells via induction of apoptotic signaling pathway.
    Asdemir A; Özgür A
    Med Oncol; 2024 Mar; 41(4):83. PubMed ID: 38436810
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Efficient analysis of toxicity and mechanisms of environmental pollutants with network toxicology and molecular docking strategy: Acetyl tributyl citrate as an example.
    Huang S
    Sci Total Environ; 2023 Dec; 905():167904. PubMed ID: 37858827
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Capsaicin binds the N-terminus of hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin).
    Patwardhan CA; Kommalapati VK; Llbiyi T; Singh D; Alfa E; Horuzsko A; Korkaya H; Panda S; Reilly CA; Popik V; Chadli A
    Sci Rep; 2023 Aug; 13(1):13790. PubMed ID: 37612326
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Identification and validation of a novel overall survival prediction model for immune-related genes in bone metastases of prostate cancer.
    Bi W; Guo W; Fan G; Xie L; Jiang C
    Aging (Albany NY); 2023 Jul; 15(14):7161-7186. PubMed ID: 37494663
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Emodin-Induced Necroptosis in prostate cancer Cells via the Mitochondrial Fission hsp90/MLKL/PGAM Pathway.
    Zhou X; Yeasmin Khusbu F; Xie Y; Yang P
    Chem Biodivers; 2023 Jun; 20(6):e202201130. PubMed ID: 37062702
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Role of Ganetespib, an hsp90 Inhibitor, in cancer Therapy: From Molecular Mechanisms to Clinical Practice.
    Youssef ME; Cavalu S; Hasan AM; Yahya G; Abd-Eldayem MA; Saber S
    Int J Mol Sci; 2023 Mar; 24(5):. PubMed ID: 36902446
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Protein Kinase D3 (PKD3) Requires hsp90 for Stability and Promotion of prostate cancer Cell Migration.
    Varga A; Nguyen MT; Pénzes K; Bátai B; Gyulavári P; Gurbi B; Murányi J; Csermely P; Csala M; Vántus T; Sőti C
    Cells; 2023 Jan; 12(2):. PubMed ID: 36672148
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Risk of secondary tumours in patients with non-metastatic and metastatic human retinoblastoma.
    Sadeghi R; Pirankuraim H; Javanshir ST; Arabi M; Bereimipour A; Javanshir HT; Mahmoodzadeh H; Nayernia K
    Eye (Lond); 2023 Aug; 37(11):2327-2334. PubMed ID: 36528757
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Reduced HIF-1α Stability Induced by 6-Gingerol Inhibits Lung cancer Growth through the Induction of Cell Death.
    Kim MJ; Ku JM; Choi YJ; Lee SY; Hong SH; Kim HI; Shin YC; Ko SG
    Molecules; 2022 Mar; 27(7):. PubMed ID: 35408505
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Diptoindonesin G antagonizes AR signaling and enhances the efficacy of antiandrogen therapy in prostate cancer.
    Mao F; Kong Y; Liu J; Rao X; Li C; Donahue K; Zhang Y; Jones K; Zhang Q; Xu W; Liu X
    Prostate; 2022 Jun; 82(8):917-932. PubMed ID: 35322879
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. SU086, an inhibitor of hsp90, impairs glycolysis and represents a treatment strategy for advanced prostate cancer.
    Rice MA; Kumar V; Tailor D; Garcia-Marques FJ; Hsu EC; Liu S; Bermudez A; Kanchustambham V; Shankar V; Inde Z; Alabi BR; Muruganantham A; Shen M; Pandrala M; Nolley R; Aslan M; Ghoochani A; Agarwal A; Buckup M; Kumar M; Going CC; Peehl DM; Dixon SJ; Zare RN; Brooks JD; Pitteri SJ; Malhotra SV; Stoyanova T
    Cell Rep Med; 2022 Feb; 3(2):100502. PubMed ID: 35243415
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Lung cancer metastasis-related protein 1 promotes the transferring from advanced metastatic prostate cancer to castration-resistant prostate cancer by activating the glucocorticoid receptor α signal pathway.
    Wang K; Wang X; Fu X; Sun J; Zhao L; He H; Fan Y
    Bioengineered; 2022 Mar; 13(3):5373-5385. PubMed ID: 35184651
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Patient-specific Boolean models of signalling networks guide personalised treatments.
    Montagud A; Béal J; Tobalina L; Traynard P; Subramanian V; Szalai B; Alföldi R; Puskás L; Valencia A; Barillot E; Saez-Rodriguez J; Calzone L
    Elife; 2022 Feb; 11():. PubMed ID: 35164900
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Advances in the role of heat shock protein 90 in prostate cancer.
    Fu Z; Jia B
    Andrologia; 2022 May; 54(4):e14376. PubMed ID: 35075667
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Combined effect of heat shock protein inhibitor geldanamycin and free radicals on photodynamic therapy of prostate cancer.
    Sun Q; Liu F; Wen Z; Xia J; Li H; Xu Y; Sun S
    J Mater Chem B; 2022 Mar; 10(9):1369-1377. PubMed ID: 35022636
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The Andrographolide Analogue 3A.1 Synergizes with Taxane Derivatives in Aggressive Metastatic prostate cancers by Upregulation of Heat Shock Proteins and Downregulation of MAT2A-Mediated Cell Migration and Invasion.
    Mitra Ghosh T; Kansom T; Mazumder S; Davis J; Alnaim AS; Jasper SL; Zhang C; Bird A; Opanasopit P; Mitra AK; Arnold RD
    J Pharmacol Exp Ther; 2022 Mar; 380(3):180-201. PubMed ID: 34949650
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. hsp90-Specific nIR Probe Identifies Aggressive prostate cancers: Translation from Preclinical Models to a Human Phase I Study.
    Osada T; Crosby EJ; Kaneko K; Snyder JC; Ginzel JD; Acharya CR; Yang XY; Polascik TJ; Spasojevic I; Nelson RC; Hobeika A; Hartman ZC; Neckers LM; Rogatko A; Hughes PF; Huang J; Morse MA; Haystead T; Lyerly HK
    Mol Cancer Ther; 2022 Jan; 21(1):217-226. PubMed ID: 34675120
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Bruceantin targets hsp90 to overcome resistance to hormone therapy in castration-resistant prostate cancer.
    Moon SJ; Jeong BC; Kim HJ; Lim JE; Kim HJ; Kwon GY; Jackman JA; Kim JH
    Theranostics; 2021; 11(2):958-973. PubMed ID: 33391515
    [No Abstract]    [Full Text] [Related]  

  • 19. Fatty Acid Oxidation Is an Adaptive Survival Pathway Induced in prostate Tumors by hsp90 Inhibition.
    Nassar ZD; Mah CY; Centenera MM; Irani S; Sadowski MC; Scott JS; Nguyen EV; Nagarajan SR; Moldovan M; Lynn DJ; Daly RJ; Hoy AJ; Butler LM
    Mol Cancer Res; 2020 Oct; 18(10):1500-1511. PubMed ID: 32669400
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The Role of Lysosome-associated Membrane Protein 2 in prostate cancer Chemopreventive Mechanisms of Sulforaphane.
    Hahm ER; Singh KB; Kim SH; Powolny AA; Singh SV
    Cancer Prev Res (Phila); 2020 Aug; 13(8):661-672. PubMed ID: 32434809
    [TBL] [Abstract] [Full Text] [Related]  


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