Terms: = Prostate cancer AND JAK2, ENSG00000096968, O60674, JTK10, 3717 AND Treatment
38 results:
1. Butyrate increases methylglyoxal production through regulation of the jak2/Stat3/Nrf2/Glo1 pathway in castration‑resistant prostate cancer cells.
Hsia YJ; Lin ZM; Zhang T; Chou TC
Oncol Rep; 2024 May; 51(5):. PubMed ID: 38577936
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2. Enhanced synergy of pacritinib with temsirolimus and sunitinib in preclinical renal cell carcinoma model by targeting jak2/STAT pathway.
Mao F; Gao L; Liu L; Tang Y
J Chemother; 2024 May; 36(3):238-248. PubMed ID: 37916436
[TBL] [Abstract] [Full Text] [Related]
3. Polysaccharides from Lentinus edodes prevent acquired drug resistance to docetaxel in prostate cancer cells by decreasing the TGF-β1 secretion of cancer-associated fibroblasts.
Zhang W; Tao N; Bai L
J Nat Med; 2023 Sep; 77(4):817-828. PubMed ID: 37354258
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4. Discovery of PIM-1 kinase inhibitors based on the 2,5-disubstituted 1,3,4-oxadiazole scaffold against prostate cancer: Design, synthesis, in vitro and in vivo cytotoxicity investigation.
Castanet AS; Nafie MS; Said SA; Arafa RK
Eur J Med Chem; 2023 Mar; 250():115220. PubMed ID: 36848846
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5. Hypermethylation in the promoter region inhibits AJAP1 expression and activates the JAK/STAT pathway to promote prostate cancer cell migration and stem cell sphere formation.
Chen L; Wang Y; Zhang B
Pathol Res Pract; 2023 Jan; 241():154224. PubMed ID: 36566599
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6. GH Action in prostate cancer Cells Promotes Proliferation, Limits Apoptosis, and Regulates cancer-related Gene Expression.
Unterberger CJ; Maklakova VI; Lazar M; Arneson PD; Mcilwain SJ; Tsourkas PK; Hu R; Kopchick JJ; Swanson SM; Marker PC
Endocrinology; 2022 May; 163(5):. PubMed ID: 35383352
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7. A Case of Thrombotic Vasculopathy in the Setting of High-Dose Hydroxyurea Use.
Michalak J; Simman R; Oostra D
Wounds; 2021 Dec; 33(12):E79-E84. PubMed ID: 34882096
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8. Inhibition of Janus Kinase 1 synergizes docetaxel sensitivity in prostate cancer cells.
Nalairndran G; Chung I; Abdul Razack AH; Chung FF; Hii LW; Lim WM; Looi CK; Mai CW; Leong CO
J Cell Mol Med; 2021 Sep; 25(17):8187-8200. PubMed ID: 34322995
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9. β-elemonic acid inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells through the suppression of jak2/STAT3/MCL-1 and NF-ĸB signal pathways.
Bao X; Zhu J; Ren C; Zhao A; Zhang M; Zhu Z; Lu X; Zhang Y; Li X; Sima X; Li J; Zhang Q; Ma B
Chem Biol Interact; 2021 Jun; 342():109477. PubMed ID: 33878321
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10. LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway.
Jung YY; Ko JH; Um JY; Chinnathambi A; Alharbi SA; Sethi G; Ahn KS
J Cell Physiol; 2021 Jul; 236(7):5253-5264. PubMed ID: 33368314
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11. prostate cancer Growth Inhibition by 1-(3,5-Dimethylphenyl)-6-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one via Down-regulation of Phosphorylation PI3K/AKT and STA3/jak2.
Xue J; Zhang Z; Hu H
Dokl Biochem Biophys; 2020 Nov; 495(1):347-353. PubMed ID: 33368049
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12. Induction of proliferative and mutagenic activity by benzo(a)pyrene in PC-3 cells via jak2/STAT3 pathway.
Gao M; Li H; Dang F; Chen L; Liu X; Gao J
Mutat Res; 2020; 821():111720. PubMed ID: 32841893
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13. STEAP1 facilitates metastasis and epithelial-mesenchymal transition of lung adenocarcinoma via the jak2/STAT3 signaling pathway.
Huo SF; Shang WL; Yu M; Ren XP; Wen HX; Chai CY; Sun L; Hui K; Liu LH; Wei SH; Wang XX; Wang Y; Tian YX
Biosci Rep; 2020 Jun; 40(6):. PubMed ID: 32515474
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14. Enzalutamide-Induced Feed-Forward Signaling Loop Promotes Therapy-Resistant prostate cancer Growth Providing an Exploitable Molecular Target for jak2 Inhibitors.
Udhane V; Maranto C; Hoang DT; Gu L; Erickson A; Devi S; Talati PG; Banerjee A; Iczkowski KA; Jacobsohn K; See WA; Mirtti T; Kilari D; Nevalainen MT
Mol Cancer Ther; 2020 Jan; 19(1):231-246. PubMed ID: 31548294
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15. Non-coding and coding genomic variants distinguish prostate cancer, castration-resistant prostate cancer, familial prostate cancer, and metastatic castration-resistant prostate cancer from each other.
Alanazi IO; Al Shehri ZS; Ebrahimie E; Giahi H; Mohammadi-Dehcheshmeh M
Mol Carcinog; 2019 Jun; 58(6):862-874. PubMed ID: 30644608
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16. Atractylenolide II Induces Apoptosis of prostate cancer Cells through Regulation of AR and jak2/STAT3 Signaling Pathways.
Wang J; Nasser MI; Adlat S; Ming Jiang M; Jiang N; Gao L
Molecules; 2018 Dec; 23(12):. PubMed ID: 30545141
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17. Inhibitory effects of Schisandrin B on human prostate cancer cells.
Nasser MI; Han T; Adlat S; Tian Y; Jiang N
Oncol Rep; 2019 Jan; 41(1):677-685. PubMed ID: 30320364
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18. Proscillaridin A induces apoptosis, inhibits STAT3 activation and augments doxorubicin toxicity in prostate cancer cells.
He Y; Khan M; Yang J; Yao M; Yu S; Gao H
Int J Med Sci; 2018; 15(8):832-839. PubMed ID: 30008594
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19. STAT5A/B Blockade Sensitizes prostate cancer to Radiation through Inhibition of RAD51 and DNA Repair.
Maranto C; Udhane V; Hoang DT; Gu L; Alexeev V; Malas K; Cardenas K; Brody JR; Rodeck U; Bergom C; Iczkowski KA; Jacobsohn K; See W; Schmitt SM; Nevalainen MT
Clin Cancer Res; 2018 Apr; 24(8):1917-1931. PubMed ID: 29483142
[No Abstract] [Full Text] [Related]
20. Zerumbone Regulates DNA Repair Responding to Ionizing Radiation and Enhances Radiosensitivity of Human Prostatic cancer Cells.
Chiang PK; Tsai WK; Chen M; Lin WR; Chow YC; Lee CC; Hsu JM; Chen YJ
Integr Cancer Ther; 2018 Jun; 17(2):292-298. PubMed ID: 28602099
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