BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Prostate cancer AND KMT2A, TRX1, 4297, MLL, ENSG00000118058, MLL/GAS7, HTRX1, HRX, ALL-1, MLL1A, CXXC7
103 results:

  • 1. Race-specific coregulatory and transcriptomic profiles associated with DNA methylation and androgen receptor in prostate cancer.
    Ramakrishnan S; Cortes-Gomez E; Athans SR; Attwood KM; Rosario SR; Kim SJ; Mager DE; Isenhart EG; Hu Q; Wang J; Woloszynska A
    Genome Med; 2024 Apr; 16(1):52. PubMed ID: 38566104
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Exploiting epigenetic targets to overcome taxane resistance in prostate cancer.
    Cevatemre B; Bulut I; Dedeoglu B; Isiklar A; Syed H; Bayram OY; Bagci-Onder T; Acilan C
    Cell Death Dis; 2024 Feb; 15(2):132. PubMed ID: 38346967
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Unmarried status effect on stage at presentation and treatment patterns in primary urethral carcinoma patients.
    Morra S; Scheipner L; Baudo A; Jannello LMI; de Angelis M; Siech C; Goyal JA; Touma N; Tian Z; Saad F; Califano G; Celentano G; la Rocca R; Napolitano L; Shariat SF; Ahyai S; Carmignani L; de Cobelli O; Musi G; Briganti A; Chun FKH; Longo N; Karakiewicz PI
    Urol Oncol; 2024 May; 42(5):161.e17-161.e23. PubMed ID: 38320935
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Discovery of a novel, highly potent EZH2 PROTAC degrader for targeting non-canonical oncogenic functions of EZH2.
    Velez J; Dale B; Park KS; Kaniskan HÜ; Yu X; Jin J
    Eur J Med Chem; 2024 Mar; 267():116154. PubMed ID: 38295690
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Contemporary sex-specific analysis of the association of marital status with cancer-specific mortality in primary urethral carcinoma patients.
    Morra S; Scheipner L; Baudo A; Jannello LMI; de Angelis M; Siech C; Goyal JA; Touma N; Tian Z; Saad F; Creta M; Califano G; Celentano G; Shariat SF; Ahyai S; Carmignani L; de Cobelli O; Musi G; Briganti A; Chun FKH; Longo N; Karakiewicz PI
    Urol Oncol; 2024 Feb; 42(2):31.e1-31.e8. PubMed ID: 38101989
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. prostate cancer patient stratification by molecular signatures in the Veterans Precision Oncology Data Commons.
    Hernandez KM; Venkat A; Elbers DC; Bihn JR; Brophy MT; Do NV; La J; Liu Q; Prokhorenkov A; Metoki-Shlubsky N; Sung FC; Paller CJ; Fillmore NR; Grossman RL
    Cold Spring Harb Mol Case Stud; 2023 Dec; 9(4):. PubMed ID: 38050021
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.
    Ozyerli-Goknar E; Kala EY; Aksu AC; Bulut I; Cingöz A; Nizamuddin S; Biniossek M; Seker-Polat F; Morova T; Aztekin C; Kung SHY; Syed H; Tuncbag N; Gönen M; Philpott M; Cribbs AP; Acilan C; Lack NA; Onder TT; Timmers HTM; Bagci-Onder T
    Cell Commun Signal; 2023 Nov; 21(1):328. PubMed ID: 37974198
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Genetic mutations in smoking-associated prostate cancer.
    Elshafei A; Al-Toubat M; Feibus AH; Koul K; Jazayeri SB; Lelani N; Henry V; Balaji KC
    Prostate; 2023 Sep; 83(13):1229-1237. PubMed ID: 37455402
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Menin-mll1 Interaction Small Molecule Inhibitors: A Potential Therapeutic Strategy for Leukemia and cancers.
    Shi Q; Xu M; Kang Z; Zhang M; Luo Y
    Molecules; 2023 Mar; 28(7):. PubMed ID: 37049787
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Rat prostate tumors induce DNA synthesis in remote organs.
    Halin Bergström S; Lundholm M; Nordstrand A; Bergh A
    Sci Rep; 2022 May; 12(1):7908. PubMed ID: 35551231
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Menin Enhances Androgen Receptor-Independent Proliferation and Migration of prostate cancer Cells.
    Kim T; Jeong K; Kim E; Yoon K; Choi J; Park JH; Kim JH; Kim HS; Youn HD; Cho EJ
    Mol Cells; 2022 Apr; 45(4):202-215. PubMed ID: 35014621
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant prostate cancer Cells.
    Ortiz-Hernandez GL; Sanchez-Hernandez ES; Ochoa PT; Elix CC; Alkashgari HR; McMullen JRW; Soto U; Martinez SR; Diaz Osterman CJ; Mahler M; Roy S; Casiano CA
    Cells; 2021 Oct; 10(10):. PubMed ID: 34685704
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. LEDGF/p75-mediated chemoresistance of mixed-lineage leukemia involves cell survival pathways and super enhancer activators.
    Canella A; Van Belle S; Brouns T; Nigita G; Carlon MS; Christ F; Debyser Z
    Cancer Gene Ther; 2022 Feb; 29(2):133-140. PubMed ID: 33795806
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Low-Dose Tamoxifen for Mammographic Density Reduction: A Randomized Controlled Trial.
    Eriksson M; Eklund M; Borgquist S; Hellgren R; Margolin S; Thoren L; Rosendahl A; Lång K; Tapia J; Bäcklund M; Discacciati A; Crippa A; Gabrielson M; Hammarström M; Wengström Y; Czene K; Hall P
    J Clin Oncol; 2021 Jun; 39(17):1899-1908. PubMed ID: 33734864
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. High-grade tumours promote growth of other less-malignant tumours in the same prostate.
    Halin Bergström S; Rudolfsson S; Lundholm M; Josefsson A; Wikström P; Bergh A
    J Pathol; 2021 Apr; 253(4):396-403. PubMed ID: 33330991
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.
    Vatapalli R; Sagar V; Rodriguez Y; Zhao JC; Unno K; Pamarthy S; Lysy B; Anker J; Han H; Yoo YA; Truica M; Chalmers ZR; Giles F; Yu J; Chakravarti D; Carneiro B; Abdulkadir SA
    Nat Commun; 2020 Aug; 11(1):4153. PubMed ID: 32814769
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. An organoid-based drug screening identified a menin-mll inhibitor for endometrial cancer through regulating the HIF pathway.
    Chen J; Zhao L; Peng H; Dai S; Quan Y; Wang M; Wang J; Bi Z; Zheng Y; Zhou S; Liu Y; Chen C; Na F
    Cancer Gene Ther; 2021 Feb; 28(1-2):112-125. PubMed ID: 32632269
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Effects of orthotopic implantation of rat prostate tumour cells upon components of the N-acylethanolamine and monoacylglycerol signalling systems: an mRNA study.
    Alhouayek M; Stafberg L; Karlsson J; Bergström SH; Fowler CJ
    Sci Rep; 2020 Apr; 10(1):6314. PubMed ID: 32286386
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. DOT1L: a key target in normal chromatin remodelling and in mixed-lineage leukaemia treatment.
    Sarno F; Nebbioso A; Altucci L
    Epigenetics; 2020 May; 15(5):439-453. PubMed ID: 31790636
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
    Chang S; Yim S; Park H
    Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
    [TBL] [Abstract] [Full Text] [Related]  


    [Next]

    of 6.