BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Prostate cancer AND MAP2K1, MAPKK1, 5604, ENSG00000169032, Q02750, MEK1, MKK1, PRKMK1
93 results:

  • 1. Rhizochalinin Exhibits Anticancer Activity and Synergizes with EGFR Inhibitors in Glioblastoma In Vitro Models.
    Dyshlovoy SA; Hauschild J; Venz S; Krisp C; Kolbe K; Zapf S; Heinemann S; Fita KD; Shubina LK; Makarieva TN; Guzii AG; Rohlfing T; Kaune M; Busenbender T; Mair T; Moritz M; Poverennaya EV; Schlüter H; Serdyuk V; Stonik VA; Dierlamm J; Bokemeyer C; Mohme M; Westphal M; Lamszus K; von Amsberg G; Maire CL
    Mol Pharm; 2023 Oct; 20(10):4994-5005. PubMed ID: 37733943
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Computational biology and in vitro studies for anticipating cancer-related molecular targets of sweet wormwood (Artemisia annua).
    Dawood H; Celik I; Ibrahim RS
    BMC Complement Med Ther; 2023 Sep; 23(1):312. PubMed ID: 37684586
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. TRIM11 Posttranscriptionally Modulated by miR-5193 Facilitates Tumor Growth and Metastasis of prostate cancer.
    Pan Y; Yu H; Lu F
    Technol Cancer Res Treat; 2023; 22():15330338231178639. PubMed ID: 37248611
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Dual inhibition of mek1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation.
    Hoang VT; Matossian MD; La J; Hoang K; Ucar DA; Elliott S; Burks HE; Wright TD; Patel S; Bhatt A; Phamduy T; Chrisey D; Buechlein A; Rusch DB; Nephew KP; Anbalagan M; Rowan B; Cavanaugh JE; Flaherty PT; Miele L; Collins-Burow BM; Burow ME
    J Cell Biochem; 2021 Aug; 122(8):835-850. PubMed ID: 33876843
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. SOX9 in prostate cancer is upregulated by cancer-associated fibroblasts to promote tumor progression through HGF/c-Met-FRA1 signaling.
    Qin H; Yang Y; Jiang B; Pan C; Chen W; Diao W; Ding M; Cao W; Zhang Z; Chen M; Gao J; Zhao X; Qiu X; Guo H
    FEBS J; 2021 Sep; 288(18):5406-5429. PubMed ID: 33705609
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Activation of the Erk/MAPK signaling pathway is a driver for cadmium induced prostate cancer.
    Dasgupta P; Kulkarni P; Bhat NS; Majid S; Shiina M; Shahryari V; Yamamura S; Tanaka Y; Gupta RK; Dahiya R; Hashimoto Y
    Toxicol Appl Pharmacol; 2020 Aug; 401():115102. PubMed ID: 32512071
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Upregulation of pERK and c-JUN by γ-tocotrienol and not α-tocopherol are essential to the differential effect on apoptosis in prostate cancer cells.
    Moore C; Palau VE; Mahboob R; Lightner J; Stone W; Krishnan K
    BMC Cancer; 2020 May; 20(1):428. PubMed ID: 32414345
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Simulated Microgravity Influences VEGF, MAPK, and PAM Signaling in prostate cancer Cells.
    Hybel TE; Dietrichs D; Sahana J; Corydon TJ; Nassef MZ; Wehland M; Krüger M; Magnusson NE; Bauer J; Utpatel K; Infanger M; Grimm D; Kopp S
    Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32070055
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A Multifunctional Therapy Approach for cancer: Targeting Raf1- Mediated Inhibition of Cell Motility, Growth, and Interaction with the Microenvironment.
    Zhang L; Pattanayak A; Li W; Ko HK; Fowler G; Gordon R; Bergan R
    Mol Cancer Ther; 2020 Jan; 19(1):39-51. PubMed ID: 31582531
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. L-securinine inhibits cell growth and metastasis of human androgen-independent prostate cancer DU145 cells via regulating mitochondrial and AGTR1/MEK/ERK/STAT3/PAX2 apoptotic pathways.
    Zhang D; Liu H; Yang B; Hu J; Cheng Y
    Biosci Rep; 2019 May; 39(5):. PubMed ID: 30975734
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer.
    Nickols NG; Nazarian R; Zhao SG; Tan V; Uzunangelov V; Xia Z; Baertsch R; Neeman E; Gao AC; Thomas GV; Howard L; De Hoedt AM; Stuart J; Goldstein T; Chi K; Gleave ME; Graff JN; Beer TM; Drake JM; Evans CP; Aggarwal R; Foye A; Feng FY; Small EJ; Aronson WJ; Freedland SJ; Witte ON; Huang J; Alumkal JJ; Reiter RE; Rettig MB
    Prostate Cancer Prostatic Dis; 2019 Dec; 22(4):531-538. PubMed ID: 30804427
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Targeted regulation of miR-195 on map2k1 for suppressing ADM drug resistance in prostate cancer cells.
    Zhang JY; Li YN; Mu X; Pan ZL; Liu WB
    Eur Rev Med Pharmacol Sci; 2018 Dec; 22(24):8599-8608. PubMed ID: 30575899
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. MiR-203 over-expression promotes prostate cancer cell apoptosis and reduces ADM resistance.
    Chen LZ; Ding Z; Zhang Y; He ST; Wang XH
    Eur Rev Med Pharmacol Sci; 2018 Jun; 22(12):3734-3741. PubMed ID: 29949147
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Immune profiling of human prostate epithelial cells determined by expression of p38/TRAF-6/ERK MAP kinases pathways.
    Bouraoui Y; Achour M; Royuela M; Oueslati R
    Kaohsiung J Med Sci; 2018 Mar; 34(3):125-133. PubMed ID: 29475459
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Retinoblastoma protein (Rb) links hypoxia to altered mechanical properties in cancer cells as measured by an optical tweezer.
    Khakshour S; Labrecque MP; Esmaeilsabzali H; Lee FJS; Cox ME; Park EJ; Beischlag TV
    Sci Rep; 2017 Aug; 7(1):7833. PubMed ID: 28798482
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin.
    Dyshlovoy SA; Otte K; Venz S; Hauschild J; Junker H; Makarieva TN; Balabanov S; Alsdorf WH; Madanchi R; Honecker F; Bokemeyer C; Stonik VA; von Amsberg G
    Proteomics; 2017 Jun; 17(11):. PubMed ID: 28445005
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. The histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells.
    Wilson S; Fan L; Sahgal N; Qi J; Filipp FV
    Oncotarget; 2017 May; 8(18):30328-30343. PubMed ID: 28416760
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling.
    Wu J; Ivanov AI; Fisher PB; Fu Z
    Elife; 2016 Mar; 5():. PubMed ID: 27003818
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Novel roles for class II Phosphoinositide 3-Kinase C2β in signalling pathways involved in prostate cancer cell invasion.
    Mavrommati I; Cisse O; Falasca M; Maffucci T
    Sci Rep; 2016 Mar; 6():23277. PubMed ID: 26983806
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Identification of intracellular pathways through which TGF-β1 upregulates URG-4/URGCP gene expression in hepatoma cells.
    Tokay E; Kockar F
    Life Sci; 2016 Jan; 144():121-8. PubMed ID: 26657209
    [TBL] [Abstract] [Full Text] [Related]  


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