BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Prostate cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987
243 results:

  • 1. TrkA promotes mdm2-mediated AGPS ubiquitination and degradation to trigger prostate cancer progression.
    Zhang Y; Huang Z; Li K; Xie G; Feng Y; Wang Z; Li N; Liu R; Ding Y; Wang J; Yang J; Jia Z
    J Exp Clin Cancer Res; 2024 Jan; 43(1):16. PubMed ID: 38200609
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Design, Synthesis and Antitumor Activity of 1
    Wang C; Zhu M; Long X; Wang Q; Wang Z; Ouyang G
    Int J Mol Sci; 2023 May; 24(10):. PubMed ID: 37240028
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Synthesis and biological evaluation of dual mdm2/XIAP inhibitors based on the tetrahydroquinoline scaffold.
    Albadari N; Xie Y; Liu T; Wang R; Gu L; Zhou M; Wu Z; Li W
    Eur J Med Chem; 2023 Jul; 255():115423. PubMed ID: 37130471
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Inclusion of Nitrofurantoin into the Realm of cancer Chemotherapy via Biology-Oriented Synthesis and Drug Repurposing.
    Elzahhar PA; Nematalla HA; Al-Koussa H; Abrahamian C; El-Yazbi AF; Bodgi L; Bou-Gharios J; Azzi J; Al Choboq J; Labib HF; Kheir WA; Abu-Serie MM; Elrewiny MA; El-Yazbi AF; Belal ASF
    J Med Chem; 2023 Apr; 66(7):4565-4587. PubMed ID: 36921275
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Blockage of mdm2-mediated p53 ubiquitination by yuanhuacine restrains the carcinogenesis of prostate carcinoma cells by suppressing LncRNA LINC00665.
    Yan M; Li X; Gu J; Gao G; Wu Z; Xue P
    J Biochem Mol Toxicol; 2023 Mar; 37(3):e23265. PubMed ID: 36416364
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Novel spirooxindole based benzimidazole scaffold: In vitro, nanoformulation and in vivo studies on anticancer and antimetastatic activity of breast adenocarcinoma.
    Barakat A; Alshahrani S; Mohammed Al-Majid A; Saleh Alamary A; Haukka M; Abu-Serie MM; Dömling A; Mazyed EA; Badria FA; El-Senduny FF
    Bioorg Chem; 2022 Dec; 129():106124. PubMed ID: 36174446
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3β: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant prostate cancer In Vitro and In Vivo Models.
    Thomas E; Thankan RS; Purushottamachar P; Huang W; Kane MA; Zhang Y; Ambulos NP; Weber DJ; Njar VCO
    Cells; 2022 Aug; 11(17):. PubMed ID: 36078112
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. De Novo Design of an Androgen Receptor DNA Binding Domain-Targeted peptide PROTAC for prostate cancer Therapy.
    Ma B; Fan Y; Zhang D; Wei Y; Jian Y; Liu D; Wang Z; Gao Y; Ma J; Chen Y; Xu S; Li L
    Adv Sci (Weinh); 2022 Oct; 9(28):e2201859. PubMed ID: 35971165
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. lncRNA MNX1‑AS1 promotes prostate cancer progression through regulating miR‑2113/mdm2 axis.
    Liang D; Tian C; Zhang X
    Mol Med Rep; 2022 Jul; 26(1):. PubMed ID: 35616155
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. A review on the genetic polymorphisms and susceptibility of cancer patients in Bangladesh.
    Babu G; Bin Islam S; Khan MA
    Mol Biol Rep; 2022 Jul; 49(7):6725-6739. PubMed ID: 35277785
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Clinical considerations for the design of PROTACs in cancer.
    Nieto-Jiménez C; Morafraile EC; Alonso-Moreno C; Ocaña A
    Mol Cancer; 2022 Mar; 21(1):67. PubMed ID: 35249548
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Therapeutic potential of p53 reactivation in prostate cancer: Strategies and opportunities.
    Kumari S; Sharma V; Tiwari R; Maurya JP; Subudhi BB; Senapati D
    Eur J Pharmacol; 2022 Mar; 919():174807. PubMed ID: 35151649
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. K
    Ohya S; Kajikuri J; Endo K; Kito H; Matsui M
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948357
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Synthesis and Biological Evaluation of S-, O- and Se-Containing Dispirooxindoles.
    Kukushkin M; Novotortsev V; Filatov V; Ivanenkov Y; Skvortsov D; Veselov M; Shafikov R; Moiseeva A; Zyk N; Majouga A; Beloglazkina E
    Molecules; 2021 Dec; 26(24):. PubMed ID: 34946727
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Molecular imaging and treatment of PSMA-positive prostate cancer with
    Jiao Y; Xu P; Luan S; Wang X; Gao Y; Zhao C; Fu P
    Nucl Med Biol; 2022; 104-105():28-37. PubMed ID: 34847481
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Targeting KDM4A-AS1 represses AR/AR-Vs deubiquitination and enhances enzalutamide response in CRPC.
    Zhang B; Zhang M; Yang Y; Li Q; Yu J; Zhu S; Niu Y; Shang Z
    Oncogene; 2022 Jan; 41(3):387-399. PubMed ID: 34759344
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents.
    Al-Majid AM; Ali M; Islam MS; Alshahrani S; Alamary AS; Yousuf S; Choudhary MI; Barakat A
    Molecules; 2021 Oct; 26(20):. PubMed ID: 34684885
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Genetic and epigenetic bases of prostate tumor cell radioresistance.
    Kutilin D
    Klin Onkol; 2021; 34(3):220-234. PubMed ID: 34362257
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Genetic and epigenetic bases of prostate tumor cell radioresistance.
    Kutilin Denis
    Ceska Gynekol; 2021; 86(3):220-234. PubMed ID: 34192880
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Ionizing Radiation Combined with PARP1 Inhibitor Reduces Radioresistance in prostate cancer with RB1/TP53 Loss.
    Fan Y; Fan H; Quan Z; Wu X
    Cancer Invest; 2021 May; 39(5):423-434. PubMed ID: 33683975
    [TBL] [Abstract] [Full Text] [Related]  


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