Terms: = Prostate cancer AND PIM1, PIM, 5292, ENSG00000137193, P11309
131 results:
1. pim1 drives lipid droplet accumulation to promote proliferation and survival in prostate cancer.
Chauhan SS; Casillas AL; Vizzerra AD; Liou H; Clements AN; Flores CE; Prevost CT; Kashatus DF; Snider AJ; Snider JM; Warfel NA
Oncogene; 2024 Feb; 43(6):406-419. PubMed ID: 38097734
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2. pim1 targeted degradation prevents the emergence of chemoresistance in prostate cancer.
Torres-Ayuso P; Katerji M; Mehlich D; Lookingbill SA; Sabbasani VR; Liou H; Casillas AL; Chauhan SS; Serwa R; Rubin MR; Marusiak AA; Swenson RE; Warfel NA; Brognard J
Cell Chem Biol; 2024 Feb; 31(2):326-337.e11. PubMed ID: 38016478
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3. Tailored horseshoe-shaped nicotinonitrile scaffold as dual promising c-Met and pim-1 inhibitors: Design, synthesis, SAR and in silico study.
Mohamady S; Khalil AF; Naguib BH; Nafie MS; Tawfik HO; Shaldam MA
Bioorg Chem; 2024 Feb; 143():106988. PubMed ID: 37995644
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4. Design, synthesis, and evaluation of a mitoxantrone probe (MXP) for biological studies.
Wallin S; Singh S; Borgstahl GEO; Natarajan A
Bioorg Med Chem Lett; 2023 Oct; 94():129465. PubMed ID: 37669721
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5. ECL sensor for selective determination of citrate ions as a prostate cancer biomarker using polymer of intrinsic microporosity-1 nanoparticles/nitrogen-doped carbon quantum dots.
Afshary H; Amiri M; Marken F; McKeown NB; Amiri M
Anal Bioanal Chem; 2023 Jun; 415(14):2727-2736. PubMed ID: 37042993
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6. pim1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion.
Jensen CC; Clements AN; Liou H; Ball LE; Bethard JR; Langlais PR; Toth RK; Chauhan SS; Casillas AL; Daulat SR; Kraft AS; Cress AE; Miranti CK; Mouneimne G; Rogers GC; Warfel NA
J Cell Biol; 2023 Jun; 222(6):. PubMed ID: 37042842
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7. Discovery of pim-1 kinase inhibitors based on the 2,5-disubstituted 1,3,4-oxadiazole scaffold against prostate cancer: Design, synthesis, in vitro and in vivo cytotoxicity investigation.
Castanet AS; Nafie MS; Said SA; Arafa RK
Eur J Med Chem; 2023 Mar; 250():115220. PubMed ID: 36848846
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8. Discovery of new pyridine-quinoline hybrids as competitive and non-competitive pim-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities.
El-Miligy MMM; Abdelaziz ME; Fahmy SM; Ibrahim TM; Abu-Serie MM; Mahran MA; Hazzaa AA
J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2152810. PubMed ID: 36629075
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9. pim kinases phosphorylate lactate dehydrogenase A at serine 161 and suppress its nuclear ubiquitination.
Mung KL; Meinander A; Koskinen PJ
FEBS J; 2023 May; 290(9):2489-2502. PubMed ID: 36239424
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10. Development of novel cyanopyridines as pim-1 kinase inhibitors with potent anti-prostate cancer activity: Synthesis, biological evaluation, nanoparticles formulation and molecular dynamics simulation.
Ibrahim MH; Harras MF; Mostafa SK; Mohyeldin SM; Al Kamaly O; Altwaijry N; Sabour R
Bioorg Chem; 2022 Dec; 129():106122. PubMed ID: 36084418
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11. Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors.
Savill KMZ; Lee BB; Oeh J; Lin J; Lin E; Chung WJ; Young A; Chen W; Miś M; Mesh K; Eastham J; Gnad F; Jiang Z; Stawiski EW; Haley B; Daemen A; Wang X; Koeppen H; Modrusan Z; Martin SE; Sampath D; Lin K
Nat Commun; 2022 Apr; 13(1):2057. PubMed ID: 35440108
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12. Topical advances in pim kinases and their inhibitors: Medicinal chemistry perspectives.
Walhekar V; Bagul C; Kumar D; Muthal A; Achaiah G; Kulkarni R
Biochim Biophys Acta Rev Cancer; 2022 May; 1877(3):188725. PubMed ID: 35367531
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13. pim1 phosphorylation of the androgen receptor and 14-3-3 ζ regulates gene transcription in prostate cancer.
Ruff SE; Vasilyev N; Nudler E; Logan SK; Garabedian MJ
Commun Biol; 2021 Oct; 4(1):1221. PubMed ID: 34697370
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14. Investigating single amino acid substitutions in pim1 kinase: A structural genomics approach.
Shafie A; Khan S; Batra S; Anjum F; Mohammad T; Alam S; Yadav DK; Islam A; Hassan MI
PLoS One; 2021; 16(10):e0258929. PubMed ID: 34679086
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15. Therapeutic targeting of pim KINASE signaling in cancer therapy: Structural and clinical prospects.
Rathi A; Kumar D; Hasan GM; Haque MM; Hassan MI
Biochim Biophys Acta Gen Subj; 2021 Nov; 1865(11):129995. PubMed ID: 34455019
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16. Phytoconstituents and Medicinal Plants for Anticancer Drug Discovery: Computational Identification of Potent Inhibitors of pim1 Kinase.
Anjum F; Mohammad T; Almalki AA; Akhtar O; Abdullaev B; Hassan MI
OMICS; 2021 Sep; 25(9):580-590. PubMed ID: 34448628
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17. Clinical characteristics and outcomes of polypharmacy in chronic obstructive pulmonary disease patients: A cross-sectional study from Crete, Greece.
Ierodiakonou D; Theodorou E; Sifaki-Pistolla D; Bouloukaki I; Antonopoulou M; Poulorinakis I; Tsakountakis N; Voltiraki F; Chliveros K; Tsiligianni I
Clin Respir J; 2021 Dec; 15(12):1310-1319. PubMed ID: 34425633
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18. pim kinases inhibit AMPK activation and promote tumorigenicity by phosphorylating LKB1.
Mung KL; Eccleshall WB; Santio NM; Rivero-Müller A; Koskinen PJ
Cell Commun Signal; 2021 Jun; 19(1):68. PubMed ID: 34193159
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19. Expression and ERG regulation of pim kinases in prostate cancer.
Eerola SK; Kohvakka A; Tammela TLJ; Koskinen PJ; Latonen L; Visakorpi T
Cancer Med; 2021 May; 10(10):3427-3436. PubMed ID: 33932111
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20. Multi-Component Reactions of Cyclohexan-1,3-dione: Synthesis of Fused Pyran, Pyridine, Thiophene and Pyrazole Derivatives with c-Met, Anti-Proliferative Activities.
Mohareb RM; Elmetwally AM; Mohamed AA
Anticancer Agents Med Chem; 2021; 21(17):2443-2463. PubMed ID: 33438568
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