Terms: = Prostate cancer AND PTK6, BRK, 5753, ENSG00000101213, Q13882, FLJ42088
19 results:
1. Targeting protein tyrosine kinase 6 in cancer.
Gilic MB; Tyner AL
Biochim Biophys Acta Rev Cancer; 2020 Dec; 1874(2):188432. PubMed ID: 32956764
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2. Development of an autophagy-related gene expression signature for prognosis prediction in prostate cancer patients.
Hu D; Jiang L; Luo S; Zhao X; Hu H; Zhao G; Tang W
J Transl Med; 2020 Apr; 18(1):160. PubMed ID: 32264916
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3. MicroRNA-214 targets ptk6 to inhibit tumorigenic potential and increase drug sensitivity of prostate cancer cells.
Cagle P; Niture S; Srivastava A; Ramalinga M; Aqeel R; Rios-Colon L; Chimeh U; Suy S; Collins SP; Dahiya R; Kumar D
Sci Rep; 2019 Jul; 9(1):9776. PubMed ID: 31278310
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4. Vemurafenib Inhibits Active ptk6 in
Wozniak DJ; Hitchinson B; Gilic MB; Bie W; Gaponenko V; Tyner AL
Mol Cancer Ther; 2019 May; 18(5):937-946. PubMed ID: 30926642
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5. PTEN is a protein phosphatase that targets active ptk6 and inhibits ptk6 oncogenic signaling in prostate cancer.
Wozniak DJ; Kajdacsy-Balla A; Macias V; Ball-Kell S; Zenner ML; Bie W; Tyner AL
Nat Commun; 2017 Nov; 8(1):1508. PubMed ID: 29142193
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6. Descriptive characteristics of prostate cancer in patients with a history of primary male breast cancer - a SEER analysis.
Abhyankar N; Hoskins KF; Abern MR; Calip GS
BMC Cancer; 2017 Sep; 17(1):659. PubMed ID: 28946846
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7. Both genes and lncRNAs can be used as biomarkers of prostate cancer by using high throughput sequencing data.
Cheng WS; Tao H; Hu EP; Liu S; Cai HR; Tao XL; Zhang L; Mao JJ; Yan DL
Eur Rev Med Pharmacol Sci; 2014 Nov; 18(22):3504-10. PubMed ID: 25491628
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8. RSK promotes prostate cancer progression in bone through ING3, CKAP2, and ptk6-mediated cell survival.
Yu G; Lee YC; Cheng CJ; Wu CF; Song JH; Gallick GE; Yu-Lee LY; Kuang J; Lin SH
Mol Cancer Res; 2015 Feb; 13(2):348-57. PubMed ID: 25189355
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9. ptk6/brk is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors.
Peng M; Emmadi R; Wang Z; Wiley EL; Gann PH; Khan SA; Banerji N; McDonald W; Asztalos S; Pham TN; Tonetti DA; Tyner AL
Oncotarget; 2014 Aug; 5(15):6038-48. PubMed ID: 25153721
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10. Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of brk and FAK signaling.
Sallam AA; Mohyeldin MM; Foudah AI; Akl MR; Nazzal S; Meyer SA; Liu YY; El Sayed KA
Org Biomol Chem; 2014 Jul; 12(28):5295-303. PubMed ID: 24927150
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11. ptk6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer.
Zheng Y; Wang Z; Bie W; Brauer PM; Perez White BE; Li J; Nogueira V; Raychaudhuri P; Hay N; Tonetti DA; Macias V; Kajdacsy-Balla A; Tyner AL
Cancer Res; 2013 Sep; 73(17):5426-37. PubMed ID: 23856248
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12. Context-specific protein tyrosine kinase 6 (ptk6) signalling in prostate cancer.
Zheng Y; Tyner AL
Eur J Clin Invest; 2013 Apr; 43(4):397-404. PubMed ID: 23398121
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13. Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.
Zheng Y; Gierut J; Wang Z; Miao J; Asara JM; Tyner AL
Oncogene; 2013 Sep; 32(36):4304-12. PubMed ID: 23027128
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14. Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate.
Zheng Y; Asara JM; Tyner AL
J Biol Chem; 2012 Jan; 287(1):148-158. PubMed ID: 22084245
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15. The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances ptk6-mediated inhibition of β-catenin.
Brauer PM; Zheng Y; Evans MD; Dominguez-Brauer C; Peehl DM; Tyner AL
PLoS One; 2011 Mar; 6(3):e14789. PubMed ID: 21479203
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16. Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells.
Brauer PM; Zheng Y; Wang L; Tyner AL
Cell Cycle; 2010 Oct; 9(20):4190-9. PubMed ID: 20953141
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17. Building a better understanding of the intracellular tyrosine kinase ptk6 - brk by brk.
Brauer PM; Tyner AL
Biochim Biophys Acta; 2010 Aug; 1806(1):66-73. PubMed ID: 20193745
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18. A sesquiterpenelactone from Inula britannica induces anti-tumor effects dependent on Bcl-2 phosphorylation.
Rafi MM; Bai NS; Chi-Tang-Ho ; Rosen RT; White E; Perez D; Dipaola RS
Anticancer Res; 2005; 25(1A):313-8. PubMed ID: 15816553
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19. Altered localization and activity of the intracellular tyrosine kinase brk/Sik in prostate tumor cells.
Derry JJ; Prins GS; Ray V; Tyner AL
Oncogene; 2003 Jul; 22(27):4212-20. PubMed ID: 12833144
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