Terms: = Prostate cancer AND SMAD3, JV15-2, 4088, ENSG00000166949, P84022, Smad3, MADH3, HsT17436, Smad 3, DKFZp686J10186, HSPC193, DKFZP586N0721, MGC60396 AND Treatment
23 results:
1. The study of a novel CDK8 inhibitor E966-0530-45418 that inhibits prostate cancer metastasis in vitro and in vivo.
Ho TY; Sung TY; Pan SL; Huang WJ; Hsu KC; Hsu JY; Lin TE; Hsu CM; Yang CR
Biomed Pharmacother; 2023 Jun; 162():114667. PubMed ID: 37037092
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2. Docetaxel suppressed cell proliferation through smad3/HIF-1α-mediated glycolysis in prostate cancer cells.
Peng J; He Z; Yuan Y; Xie J; Zhou Y; Guo B; Guo J
Cell Commun Signal; 2022 Dec; 20(1):194. PubMed ID: 36536346
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3. Uncarboxylated osteocalcin promotes proliferation and metastasis of MDA-MB-231 cells through TGF-β/smad3 signaling pathway.
Xu J; Ma L; Wang D; Yang J
BMC Mol Cell Biol; 2022 Apr; 23(1):18. PubMed ID: 35413833
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4. Long non-‑coding RNA SNHG16 functions as a tumor activator by sponging miR‑373‑3p to regulate the TGF‑β‑R2/smad pathway in prostate cancer.
Weng W; Liu C; Li G; Ruan Q; Li H; Lin N; Chen G
Mol Med Rep; 2021 Dec; 24(6):. PubMed ID: 34643247
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5. E2F5 promotes prostate cancer cell migration and invasion through regulation of TFPI2, MMP-2 and MMP-9.
Karmakar D; Maity J; Mondal P; Shyam Chowdhury P; Sikdar N; Karmakar P; Das C; Sengupta S
Carcinogenesis; 2020 Dec; 41(12):1767-1780. PubMed ID: 32386317
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6. TOPK promotes epithelial-mesenchymal transition and invasion of breast cancer cells through upregulation of TBX3 in TGF-β1/smad signaling.
Lee YJ; Park JH; Oh SM
Biochem Biophys Res Commun; 2020 Jan; 522(1):270-277. PubMed ID: 31757421
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7. ONECUT2 is a driver of neuroendocrine prostate cancer.
Guo H; Ci X; Ahmed M; Hua JT; Soares F; Lin D; Puca L; Vosoughi A; Xue H; Li E; Su P; Chen S; Nguyen T; Liang Y; Zhang Y; Xu X; Xu J; Sheahan AV; Ba-Alawi W; Zhang S; Mahamud O; Vellanki RN; Gleave M; Bristow RG; Haibe-Kains B; Poirier JT; Rudin CM; Tsao MS; Wouters BG; Fazli L; Feng FY; Ellis L; van der Kwast T; Berlin A; Koritzinsky M; Boutros PC; Zoubeidi A; Beltran H; Wang Y; He HH
Nat Commun; 2019 Jan; 10(1):278. PubMed ID: 30655535
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8. Nur77 suppression facilitates androgen deprivation-induced cell invasion of prostate cancer cells mediated by TGF-β signaling.
Wu J; Sun H; Yang X; Sun X
Clin Transl Oncol; 2018 Oct; 20(10):1302-1313. PubMed ID: 29594945
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9. Identification of mechanisms of resistance to treatment with abiraterone acetate or enzalutamide in patients with castration-resistant prostate cancer (CRPC).
Pal SK; Patel J; He M; Foulk B; Kraft K; Smirnov DA; Twardowski P; Kortylewski M; Bhargava V; Jones JO
Cancer; 2018 Mar; 124(6):1216-1224. PubMed ID: 29266182
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10. Potent Inhibition of miR-34b on Migration and Invasion in Metastatic prostate cancer Cells by Regulating the TGF-β Pathway.
Fang LL; Sun BF; Huang LR; Yuan HB; Zhang S; Chen J; Yu ZJ; Luo H
Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29257105
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11. Galangin enhances TGF-β1-mediated growth inhibition by suppressing phosphorylation of threonine 179 residue in smad3 linker region.
Kwak MK; Yang KM; Park J; Lee S; Park Y; Hong E; Sun EJ; An H; Park S; Pang K; Lee J; Kang JM; Kim P; Ooshima A; Kim SJ
Biochem Biophys Res Commun; 2017 Dec; 494(3-4):706-713. PubMed ID: 29097203
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12. Thymoquinone inhibits epithelial-mesenchymal transition in prostate cancer cells by negatively regulating the TGF-β/smad2/3 signaling pathway.
Kou B; Liu W; Zhao W; Duan P; Yang Y; Yi Q; Guo F; Li J; Zhou J; Kou Q
Oncol Rep; 2017 Dec; 38(6):3592-3598. PubMed ID: 29039572
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13. miR-2909 regulates ISGylation system via STAT1 signalling through negative regulation of SOCS3 in prostate cancer.
Ayub SG; Kaul D
Andrology; 2017 Jul; 5(4):790-797. PubMed ID: 28622443
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14. Deregulated E2F5/p38/smad3 Circuitry Reinforces the Pro-Tumorigenic Switch of TGFβ Signaling in prostate cancer.
Majumder S; Bhowal A; Basu S; Mukherjee P; Chatterji U; Sengupta S
J Cell Physiol; 2016 Nov; 231(11):2482-92. PubMed ID: 26919443
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15. Cryoablation induced the change of TGF-β pathway in CWR-22RV prostate cancer cell line.
Nailing T; Zhi G; Xueling Y
Cryobiology; 2015 Aug; 71(1):130-4. PubMed ID: 25952505
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16. Transcriptional activation by NFκB increases perlecan/HSPG2 expression in the desmoplastic prostate tumor microenvironment.
Warren CR; Grindel BJ; Francis L; Carson DD; Farach-Carson MC
J Cell Biochem; 2014 Jul; 115(7):1322-33. PubMed ID: 24700612
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17. Apigenin inhibits TGF-β-induced VEGF expression in human prostate carcinoma cells via a smad2/3- and Src-dependent mechanism.
Mirzoeva S; Franzen CA; Pelling JC
Mol Carcinog; 2014 Aug; 53(8):598-609. PubMed ID: 23359392
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18. Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.
Baniwal SK; Khalid O; Gabet Y; Shah RR; Purcell DJ; Mav D; Kohn-Gabet AE; Shi Y; Coetzee GA; Frenkel B
Mol Cancer; 2010 Sep; 9():258. PubMed ID: 20863401
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19. [Literature-mining and bioinformatic analysis of androgen-independent prostate cancer-specific genes].
Li TQ; Feng CQ; Zou YG; Shi R; Liang S; Mao XM
Zhonghua Nan Ke Xue; 2009 Dec; 15(12):1102-7. PubMed ID: 20180422
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20. BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo.
Buijs JT; Rentsch CA; van der Horst G; van Overveld PG; Wetterwald A; Schwaninger R; Henriquez NV; Ten Dijke P; Borovecki F; Markwalder R; Thalmann GN; Papapoulos SE; Pelger RC; Vukicevic S; Cecchini MG; Löwik CW; van der Pluijm G
Am J Pathol; 2007 Sep; 171(3):1047-57. PubMed ID: 17724140
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