Terms: = Prostate cancer AND XPO1, DKFZp686B1823, 7514, ENSG00000082898, O14980, CRM1
26 results:
1. Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation.
Kim WK; Buckley AJ; Lee DH; Hiroto A; Nenninger CH; Olson AW; Wang J; Li Z; Vikram R; Adzavon YM; Yau TY; Bao Y; Kahn M; Geradts J; Xiao GQ; Sun Z
Nat Commun; 2024 Feb; 15(1):1231. PubMed ID: 38336745
[TBL] [Abstract] [Full Text] [Related]
2. Selinexor in combination with weekly paclitaxel in patients with metastatic solid tumors: Results of an open label, single-center, multi-arm phase 1b study with expansion phase in ovarian cancer.
Westin SN; Fu S; Tsimberidou A; Piha-Paul S; Akhmedzhanov F; Yilmaz B; McQuinn L; Brink AL; Gong J; Leung CH; Lin H; Hong DS; Pant S; Carter B; Jazaeri A; Gershenson D; Sood AK; Coleman RL; Shah J; Meric-Bernstam F; Naing A
Gynecol Oncol; 2023 Jan; 168():76-82. PubMed ID: 36423446
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3. The efficacy of selinexor (KPT-330), an xpo1 inhibitor, on non-hematologic cancers: a comprehensive review.
Landes JR; Moore SA; Bartley BR; Doan HQ; Rady PL; Tyring SK
J Cancer Res Clin Oncol; 2023 May; 149(5):2139-2155. PubMed ID: 35941226
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4. PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer.
Galbraith LCA; Mui E; Nixon C; Hedley A; Strachan D; MacKay G; Sumpton D; Sansom OJ; Leung HY; Ahmad I
Oncogene; 2021 Apr; 40(13):2355-2366. PubMed ID: 33654198
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5. Differential tissue expression of extracellular vesicle-derived proteins in prostate cancer.
Duijvesz D; Rodriguez-Blanco G; Hoogland AM; Verhoef EI; Dekker LJ; Roobol MJ; van Leenders GJLH; Luider TM; Jenster G
Prostate; 2019 Jun; 79(9):1032-1042. PubMed ID: 31018022
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6. Estrogen receptors localization and signaling pathways in DU-145 human prostate cancer cells.
Souza DS; Lombardi APG; Vicente CM; Lucas TFG; Erustes AG; Pereira GJS; Porto CS
Mol Cell Endocrinol; 2019 Mar; 483():11-23. PubMed ID: 30660702
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7. A Phase II Trial of Selinexor, an Oral Selective Inhibitor of Nuclear Export Compound, in Abiraterone- and/or Enzalutamide-Refractory Metastatic Castration-Resistant prostate cancer.
Wei XX; Siegel AP; Aggarwal R; Lin AM; Friedlander TW; Fong L; Kim W; Louttit M; Chang E; Zhang L; Ryan CJ
Oncologist; 2018 Jun; 23(6):656-e64. PubMed ID: 29487219
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8. Diagnostic value of semi-quantitative and quantitative analysis of functional parameters in multiparametric MRI of the prostate.
Hauth E; Halbritter D; Jaeger H; Hohmuth H; Beer M
Br J Radiol; 2017 Oct; 90(1078):20170067. PubMed ID: 28749167
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9. KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models.
Gravina GL; Mancini A; Sanita P; Vitale F; Marampon F; Ventura L; Landesman Y; McCauley D; Kauffman M; Shacham S; Festuccia C
BMC Cancer; 2015 Dec; 15():941. PubMed ID: 26620414
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10. Cytoplasmic PML promotes TGF-β-associated epithelial-mesenchymal transition and invasion in prostate cancer.
Buczek ME; Miles AK; Green W; Johnson C; Boocock DJ; Pockley AG; Rees RC; Hulman G; van Schalkwyk G; Parkinson R; Hulman J; Powe DG; Regad T
Oncogene; 2016 Jun; 35(26):3465-75. PubMed ID: 26549027
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11. Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models.
Gravina GL; Mancini A; Scarsella L; Colapietro A; Jitariuc A; Vitale F; Marampon F; Ricevuto E; Festuccia C
Tumour Biol; 2016 Jan; 37(1):341-51. PubMed ID: 26219891
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12. xpo1/crm1-selective inhibitors of nuclear export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa).
Gravina GL; Tortoreto M; Mancini A; Addis A; Di Cesare E; Lenzi A; Landesman Y; McCauley D; Kauffman M; Shacham S; Zaffaroni N; Festuccia C
J Hematol Oncol; 2014 Oct; 7():46. PubMed ID: 25284315
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13. Selective inhibitors of nuclear export (SINE) as novel therapeutics for prostate cancer.
Mendonca J; Sharma A; Kim HS; Hammers H; Meeker A; De Marzo A; Carducci M; Kauffman M; Shacham S; Kachhap S
Oncotarget; 2014 Aug; 5(15):6102-12. PubMed ID: 25026284
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14. Torc1/Torc2 inhibitor, Palomid 529, enhances radiation response modulating crm1-mediated survivin function and delaying DNA repair in prostate cancer models.
Gravina GL; Marampon F; Sherris D; Vittorini F; Di Cesare E; Tombolini V; Lenzi A; Jannini EA; Festuccia C
Prostate; 2014 Jun; 74(8):852-68. PubMed ID: 24715588
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15. Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
Duijvesz D; Burnum-Johnson KE; Gritsenko MA; Hoogland AM; Vredenbregt-van den Berg MS; Willemsen R; Luider T; Paša-Tolić L; Jenster G
PLoS One; 2013; 8(12):e82589. PubMed ID: 24391718
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16. Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling.
Beckham TH; Cheng JC; Lu P; Marrison ST; Norris JS; Liu X
PLoS One; 2013; 8(10):e76593. PubMed ID: 24098536
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17. DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells.
Iio A; Takagi T; Miki K; Naoe T; Nakayama A; Akao Y
Biochim Biophys Acta; 2013 Oct; 1829(10):1102-10. PubMed ID: 23932921
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18. PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and crm1 in preclinical models of prostate cancer.
Gravina GL; Marampon F; Muzi P; Mancini A; Piccolella M; Negri-Cesi P; Motta M; Lenzi A; Di Cesare E; Tombolini V; Jannini EA; Festuccia C
Endocr Relat Cancer; 2013 Jun; 20(3):321-37. PubMed ID: 23507703
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19. Selective inhibitors of nuclear export block pancreatic cancer cell proliferation and reduce tumor growth in mice.
Azmi AS; Aboukameel A; Bao B; Sarkar FH; Philip PA; Kauffman M; Shacham S; Mohammad RM
Gastroenterology; 2013 Feb; 144(2):447-456. PubMed ID: 23089203
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20. Critical role of N-terminal end-localized nuclear export signal in regulation of activating transcription factor 2 (ATF2) subcellular localization and transcriptional activity.
Hsu CC; Hu CD
J Biol Chem; 2012 Mar; 287(11):8621-32. PubMed ID: 22275354
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