Terms: = Sarcomas AND CXCR4, D2S201E, 7852, ENSG00000121966, P61073, NPYY3R, NPY3R, HM89, NPYRL, LESTR, HSY3RR, LCR1, fusin, WHIM, NPYR, FB22, CD184 AND Treatment
40 results:
1. Caulis Spatholobi extracts inhibit osteosarcoma growth and metastasis through suppression of cxcr4/PI3K/AKT signaling.
Jiang Y; Gao Y; Li X; He F; Liu Y; Wang R
J Orthop Surg Res; 2023 Dec; 18(1):985. PubMed ID: 38129870
[TBL] [Abstract] [Full Text] [Related]
2. cxcr4-Directed Imaging and Endoradiotherapy in Desmoplastic Small Round Cell Tumors.
Hartlapp I; Hartrampf PE; Serfling SE; Wild V; Weich A; Rasche L; Roth S; Rosenwald A; Mihatsch PW; Hendricks A; Wiegering A; Wiegering V; Hänscheid H; Schirbel A; Werner RA; Buck AK; Wester HJ; Einsele H; Kunzmann V; Lapa C; Kortüm KM
J Nucl Med; 2023 Sep; 64(9):1424-1430. PubMed ID: 37348915
[TBL] [Abstract] [Full Text] [Related]
3. cxcr4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K‑Akt‑mTOR pathway inhibition.
Liao YX; Lv JY; Zhou ZF; Xu TY; Yang D; Gao QM; Fan L; Li GD; Yu HY; Liu KY
Int J Oncol; 2021 Jul; 59(1):. PubMed ID: 34080667
[TBL] [Abstract] [Full Text] [Related]
4. Vincetoxicum arnottianum modulates motility features and metastatic marker expression in pediatric rhabdomyosarcoma by stabilizing the actin cytoskeleton.
Adamus A; Ali I; Vasileiadis V; Al-Hileh L; Lisec J; Frank M; Seitz G; Engel N
BMC Complement Med Ther; 2021 May; 21(1):136. PubMed ID: 33947373
[TBL] [Abstract] [Full Text] [Related]
5. The effect of microRNA-330 replacement on inhibition of growth and migration in renal cancer cells.
Liu J; Song X; Ren Z
Biotechnol Appl Biochem; 2022 Apr; 69(2):558-566. PubMed ID: 33605482
[TBL] [Abstract] [Full Text] [Related]
6. The response of PIK3CA/KRAS-mutant colorectal cancer stem-like cells to RGD-peptide FraC produced by the strawberry anemone: A promising water-soluble peptide-based inhibitor of metastasis-driver gene cxcr4, stem cell regulatory genes and self-renewal.
Sarkhosh-Inanlou R; Imani M; Sam MR
Biomed Pharmacother; 2020 Dec; 132():110807. PubMed ID: 33068939
[TBL] [Abstract] [Full Text] [Related]
7. miR-192 enhances sensitivity of methotrexate drug to MG-63 osteosarcoma cancer cells.
Bazavar M; Fazli J; Valizadeh A; Ma B; Mohammadi E; Asemi Z; Alemi F; Maleki M; Xing S; Yousefi B
Pathol Res Pract; 2020 Nov; 216(11):153176. PubMed ID: 32861171
[TBL] [Abstract] [Full Text] [Related]
8. Cytotoxic drugs in combination with the cxcr4 antagonist AMD3100 as a potential treatment option for pediatric rhabdomyosarcoma.
Regenbogen S; Stagno MJ; Schleicher S; Schilbach K; Bösmüller H; Fuchs J; Schmid E; Seitz G
Int J Oncol; 2020 Jul; 57(1):289-300. PubMed ID: 32377699
[TBL] [Abstract] [Full Text] [Related]
9. The Role of C-X-C Chemokine Receptor Type 4 (cxcr4) in Cell Adherence and Spheroid Formation of Human Ewing's Sarcoma Cells under Simulated Microgravity.
Romswinkel A; Infanger M; Dietz C; Strube F; Kraus A
Int J Mol Sci; 2019 Dec; 20(23):. PubMed ID: 31810195
[TBL] [Abstract] [Full Text] [Related]
10. PTEN loss activates a functional AKT/cxcr4 signaling axis to potentiate tumor growth and lung metastasis in human osteosarcoma cells.
Xi Y; Qi Z; Ma J; Chen Y
Clin Exp Metastasis; 2020 Feb; 37(1):173-185. PubMed ID: 31571016
[TBL] [Abstract] [Full Text] [Related]
11. Galectin-1 inhibition induces cell apoptosis through dual suppression of cxcr4 and Ras pathways in human malignant peripheral nerve sheath tumors.
Shih TC; Fan Y; Kiss S; Li X; Deng XN; Liu R; Chen XJ; Carney R; Chen A; Ghosh PM; Lam KS
Neuro Oncol; 2019 Nov; 21(11):1389-1400. PubMed ID: 31127849
[TBL] [Abstract] [Full Text] [Related]
12. Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma.
Li B; Wang Z; Wu H; Xue M; Lin P; Wang S; Lin N; Huang X; Pan W; Liu M; Yan X; Qu H; Sun L; Li H; Wu Y; Teng W; Wang Z; Zhou X; Chen H; Poznansky MC; Ye Z
Cancer Res; 2018 Jul; 78(14):3938-3953. PubMed ID: 29735547
[TBL] [Abstract] [Full Text] [Related]
13. Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells.
Megiorni F; Gravina GL; Camero S; Ceccarelli S; Del Fattore A; Desiderio V; Papaccio F; McDowell HP; Shukla R; Pizzuti A; Beirinckx F; Pujuguet P; Saniere L; der Aar EV; Maggio R; De Felice F; Marchese C; Dominici C; Tombolini V; Festuccia C; Marampon F
J Hematol Oncol; 2017 Oct; 10(1):161. PubMed ID: 28985758
[TBL] [Abstract] [Full Text] [Related]
14. Altered CXCL12 expression reveals a dual role of cxcr4 in osteosarcoma primary tumor growth and metastasis.
Neklyudova O; Arlt MJ; Brennecke P; Thelen M; Gvozdenovic A; Kuzmanov A; Robl B; Botter SM; Born W; Fuchs B
J Cancer Res Clin Oncol; 2016 Aug; 142(8):1739-50. PubMed ID: 27300512
[TBL] [Abstract] [Full Text] [Related]
15. Sinomenine prevents metastasis of human osteosarcoma cells via S phase arrest and suppression of tumor-related neovascularization and osteolysis through the cxcr4-STAT3 pathway.
Xie T; Ren HY; Lin HQ; Mao JP; Zhu T; Wang SD; Ye ZM
Int J Oncol; 2016 May; 48(5):2098-112. PubMed ID: 26983669
[TBL] [Abstract] [Full Text] [Related]
16. Novel splice variants of cxcr4 identified by transcriptome sequencing.
Sand LG; Jochemsen AG; Beletkaia E; Schmidt T; Hogendoorn PC; Szuhai K
Biochem Biophys Res Commun; 2015 Oct; 466(1):89-94. PubMed ID: 26321665
[TBL] [Abstract] [Full Text] [Related]
17. miR-181a Targets RGS16 to Promote Chondrosarcoma Growth, Angiogenesis, and Metastasis.
Sun X; Charbonneau C; Wei L; Chen Q; Terek RM
Mol Cancer Res; 2015 Sep; 13(9):1347-57. PubMed ID: 26013170
[TBL] [Abstract] [Full Text] [Related]
18. AMD3100 reduces cxcr4-mediated survival and metastasis of osteosarcoma by inhibiting JNK and Akt, but not p38 or Erk1/2, pathways in in vitro and mouse experiments.
Liao YX; Fu ZZ; Zhou CH; Shan LC; Wang ZY; Yin F; Zheng LP; Hua YQ; Cai ZD
Oncol Rep; 2015 Jul; 34(1):33-42. PubMed ID: 25997540
[TBL] [Abstract] [Full Text] [Related]
19. The HIF-1α/cxcr4 pathway supports hypoxia-induced metastasis of human osteosarcoma cells.
Guan G; Zhang Y; Lu Y; Liu L; Shi D; Wen Y; Yang L; Ma Q; Liu T; Zhu X; Qiu X; Zhou Y
Cancer Lett; 2015 Feb; 357(1):254-264. PubMed ID: 25444927
[TBL] [Abstract] [Full Text] [Related]
20. SDF-1/cxcr4 signaling up-regulates survivin to regulate human sacral chondrosarcoma cell cycle and epithelial-mesenchymal transition via ERK and PI3K/AKT pathway.
Yang P; Wang G; Huo H; Li Q; Zhao Y; Liu Y
Med Oncol; 2015 Jan; 32(1):377. PubMed ID: 25428386
[TBL] [Abstract] [Full Text] [Related]
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