Terms: = Sarcomas AND FGFR1, CEK, 2260, ENSG00000077782, P11362, FLT2, CD331, H3, HBGFR, FGFBR, H5, KAL2, H2, BFGFR, N-SAM, H4 AND Treatment
123 results:
1. A high-content screen of FDA approved drugs to enhance CAR T cell function: ingenol-3-angelate improves B7-H3-CAR T cell activity by upregulating B7-H3 on the target cell surface via PKCα activation.
Lee HW; O'Reilly C; Beckett AN; Currier DG; Chen T; DeRenzo C
J Exp Clin Cancer Res; 2024 Apr; 43(1):97. PubMed ID: 38561833
[TBL] [Abstract] [Full Text] [Related]
2. FGF2 drives osteosarcoma metastasis through activating fgfr1-4 receptor pathway-mediated ICAM-1 expression.
Huang YC; Chen WC; Yu CL; Chang TK; I-Chin Wei A; Chang TM; Liu JF; Wang SW
Biochem Pharmacol; 2023 Dec; 218():115853. PubMed ID: 37832794
[TBL] [Abstract] [Full Text] [Related]
3. Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study.
Pant S; Schuler M; Iyer G; Witt O; Doi T; Qin S; Tabernero J; Reardon DA; Massard C; Minchom A; Lugowska I; Carranza O; Arnold D; Gutierrez M; Winter H; Stuyckens K; Crow L; Najmi S; Hammond C; Thomas S; Santiago-Walker A; Triantos S; Sweiti H; Loriot Y;
Lancet Oncol; 2023 Aug; 24(8):925-935. PubMed ID: 37541273
[TBL] [Abstract] [Full Text] [Related]
4. Establishment and characterization of two novel patient-derived cell lines from giant cell tumor of bone.
Ono T; Noguchi R; Yoshimatsu Y; Sin Y; Tsuchiya R; Akiyama T; Kojima N; Toda Y; Sato C; Fukushima S; Yoshida A; Kawai A; Kondo T
Hum Cell; 2023 Sep; 36(5):1804-1812. PubMed ID: 37328637
[TBL] [Abstract] [Full Text] [Related]
5. Targeting B7-H3-A Novel Strategy for the Design of Anticancer Agents for Extracranial Pediatric Solid Tumors treatment.
Rasic P; Jeremic M; Jeremic R; Dusanovic Pjevic M; Rasic M; Djuricic SM; Milickovic M; Vukadin M; Mijovic T; Savic D
Molecules; 2023 Apr; 28(8):. PubMed ID: 37110590
[TBL] [Abstract] [Full Text] [Related]
6. Switchable CAR T cell strategy against osteosarcoma.
Hidalgo L; Somovilla-Crespo B; Garcia-Rodriguez P; Morales-Molina A; Rodriguez-Milla MA; Garcia-Castro J
Cancer Immunol Immunother; 2023 Aug; 72(8):2623-2633. PubMed ID: 37062034
[TBL] [Abstract] [Full Text] [Related]
7. KSHV hijacks FoxO1 to promote cell proliferation and cellular transformation by antagonizing oxidative stress.
Li T; Gao SJ
J Med Virol; 2023 Mar; 95(3):e28676. PubMed ID: 36929740
[TBL] [Abstract] [Full Text] [Related]
8. RhRu Alloy-Anchored MXene Nanozyme for Synergistic Osteosarcoma Therapy.
Liang Y; Liao C; Guo X; Li G; Yang X; Yu J; Zhong J; Xie Y; Zheng L; Zhao J
Small; 2023 Jun; 19(22):e2205511. PubMed ID: 36871143
[TBL] [Abstract] [Full Text] [Related]
9. Alpha Ketoglutarate Downregulates the Neutral Endopeptidase and Enhances the Growth Inhibitory Activity of Thiorphan in Highly Aggressive Osteosarcoma Cells.
Mizerska-Kowalska M; Sławińska-Brych A; Niedziela E; Brodovskiy V; Zdzisińska B
Molecules; 2022 Dec; 28(1):. PubMed ID: 36615293
[TBL] [Abstract] [Full Text] [Related]
10. Collaborative Design of MgO/FeO
Zhang D; Tan J; Xu R; Du H; Xie J; Peng F; Liu X
Small; 2023 Feb; 19(5):e2204852. PubMed ID: 36464630
[TBL] [Abstract] [Full Text] [Related]
11. B7-H3 targeted CAR-T cells show highly efficient anti-tumor function against osteosarcoma both in vitro and in vivo.
Zhang Q; Zhang Z; Liu G; Li D; Gu Z; Zhang L; Pan Y; Cui X; Wang L; Liu G; Tian X; Zhang Z
BMC Cancer; 2022 Nov; 22(1):1124. PubMed ID: 36320072
[TBL] [Abstract] [Full Text] [Related]
12. B7-H3-targeting Fc-optimized antibody for induction of NK cell reactivity against sarcoma.
Hagelstein I; Engel M; Hinterleitner C; Manz T; Märklin M; Jung G; Salih HR; Zekri L
Front Immunol; 2022; 13():1002898. PubMed ID: 36275693
[TBL] [Abstract] [Full Text] [Related]
13. Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cottone L; Ligammari L; Lee HM; Knowles HJ; Henderson S; Bianco S; Davies C; Strauss S; Amary F; Leite AP; Tirabosco R; Haendler K; Schultze JL; Herrero J; O'Donnell P; Grigoriadis AE; Salomoni P; Flanagan AM
Cell Death Differ; 2022 Dec; 29(12):2459-2471. PubMed ID: 36138226
[TBL] [Abstract] [Full Text] [Related]
14. Osteosarcoma with cell-cycle and fibroblast growth factor genomic alterations: case report of Molecular Tumor Board combination strategy resulting in long-term exceptional response.
Persha HE; Kato S; De P; Adashek JJ; Sicklick JK; Subbiah V; Kurzrock R
J Hematol Oncol; 2022 Aug; 15(1):119. PubMed ID: 36031605
[TBL] [Abstract] [Full Text] [Related]
15. Dramatic response to entrectinib in a patient with malignant peripheral nerve sheath tumor harboring novel SNRNP70-NTRK3 fusion gene.
Kobayashi H; Makise N; Shinozaki-Ushiku A; Zhang L; Ishibashi Y; Ikegami M; Tsuda Y; Kohsaka S; Ushiku T; Oda K; Miyagawa K; Aburatani H; Mano H; Tanaka S
Genes Chromosomes Cancer; 2023 Jan; 62(1):47-51. PubMed ID: 35906852
[TBL] [Abstract] [Full Text] [Related]
16. Targeting Enhancer of Zeste Homolog 2 for the treatment of Hematological Malignancies and Solid Tumors: Candidate Structure-Activity Relationships Insights and Evolution Prospects.
Xia J; Li J; Tian L; Ren X; Liu C; Liang C
J Med Chem; 2022 May; 65(10):7016-7043. PubMed ID: 35531606
[TBL] [Abstract] [Full Text] [Related]
17. KDM5B promotes tumorigenesis of Ewing sarcoma via FBXW7/CCNE1 axis.
Chen B; Chen H; Lu S; Zhu X; Que Y; Zhang Y; Huang J; Zhang L; Zhang Y; Sun F; Wang J; Zhu J; Zhen Z; Zhang Y
Cell Death Dis; 2022 Apr; 13(4):354. PubMed ID: 35428764
[TBL] [Abstract] [Full Text] [Related]
18. B7-H3 Specific CAR T Cells for the Naturally Occurring, Spontaneous Canine Sarcoma Model.
Zhang S; Black RG; Kohli K; Hayes BJ; Miller C; Koehne A; Schroeder BA; Abrams K; Schulte BC; Alexiev BA; Heimberger AB; Zhang A; Jing W; Ng JCK; Shinglot H; Seguin B; Salter AI; Riddell SR; Jensen MC; Gottschalk S; Moore PF; Torok-Storb B; Pollack SM
Mol Cancer Ther; 2022 Jun; 21(6):999-1009. PubMed ID: 35405743
[TBL] [Abstract] [Full Text] [Related]
19. Local anesthetic levobupivacaine inhibits stemness of osteosarcoma cells by epigenetically repressing MAFB though reducing KAT5 expression.
Wang Z; Song Y; Zhang H; Yang Y; Zhang S; Wang W
Aging (Albany NY); 2022 Mar; 14(6):2793-2804. PubMed ID: 35333774
[TBL] [Abstract] [Full Text] [Related]
20. Diagnostic Utility of Genetic and Immunohistochemical
Wągrodzki M; Tysarowski A; Seliga K; Wojnowska A; Stepaniuk M; Castañeda Wysocka P; Makuła D; Pieńkowski A; Szostakowski B; Zub R; Rutkowski P
Int J Mol Sci; 2022 Jan; 23(2):. PubMed ID: 35055156
[TBL] [Abstract] [Full Text] [Related]
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