BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Sarcomas AND FGFR4, CD334, 2264, ENSG00000160867, P22455, MGC20292, TKF, JTK2
52 results:

  • 1. A Case Study of a Rare Undifferentiated Spindle Cell Sarcoma of the Penis: Establishment and Characterization of Patient-Derived Models.
    Sousa ACDS; Fernandes BLNC; da Silva JPA; Stevanato Filho PR; Coimbra LBCT; de Oliveira Beserra A; Alvarenga AL; Maida G; Guimaraes CT; Nakamuta IM; Marchi FA; Alves C; Lichtenfels M; de Farias CB; Kupper BEC; Costa FD; de Mello CAL; Carraro DM; Torrezan GT; Lopes A; Dos Santos TG
    Genes (Basel); 2024 Mar; 15(4):. PubMed ID: 38674359
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. FGF2 drives osteosarcoma metastasis through activating FGFR1-4 receptor pathway-mediated ICAM-1 expression.
    Huang YC; Chen WC; Yu CL; Chang TK; I-Chin Wei A; Chang TM; Liu JF; Wang SW
    Biochem Pharmacol; 2023 Dec; 218():115853. PubMed ID: 37832794
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Preclinical development of a chimeric antigen receptor T cell therapy targeting fgfr4 in rhabdomyosarcoma.
    Tian M; Wei JS; Shivaprasad N; Highfill SL; Gryder BE; Milewski D; Brown GT; Moses L; Song H; Wu JT; Azorsa P; Kumar J; Schneider D; Chou HC; Song YK; Rahmy A; Masih KE; Kim YY; Belyea B; Linardic CM; Dropulic B; Sullivan PM; Sorensen PH; Dimitrov DS; Maris JM; Mackall CL; Orentas RJ; Cheuk AT; Khan J
    Cell Rep Med; 2023 Oct; 4(10):101212. PubMed ID: 37774704
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Surfaceome Profiling of Cell Lines and Patient-Derived Xenografts Confirm fgfr4, NCAM1, CD276, and Highlight AGRL2, JAM3, and L1CAM as Surface Targets for Rhabdomyosarcoma.
    Timpanaro A; Piccand C; Uldry AC; Bode PK; Dzhumashev D; Sala R; Heller M; Rössler J; Bernasconi M
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768928
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Strategies to inhibit fgfr4 V550L-driven rhabdomyosarcoma.
    Fiorito E; Szybowska P; Haugsten EM; Kostas M; Øy GF; Wiedlocha A; Singh S; Nakken S; Mælandsmo GM; Fletcher JA; Meza-Zepeda LA; Wesche J
    Br J Cancer; 2022 Nov; 127(11):1939-1953. PubMed ID: 36097178
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. fgfr4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma.
    Sullivan PM; Kumar R; Li W; Hoglund V; Wang L; Zhang Y; Shi M; Beak D; Cheuk A; Jensen MC; Khan J; Dimitrov DS; Orentas RJ
    Mol Cancer Ther; 2022 Oct; 21(10):1608-1621. PubMed ID: 35877472
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Mutational landscape of primary breast angiosarcoma with repeated resection and recurrence over a 15-year period: A case report.
    Teruyama F; Kuno A; Murata Y; Nakagawa T; Shiba-Ishii A; Yuguchi S; Noguchi M
    Pathol Int; 2022 Sep; 72(9):457-463. PubMed ID: 35801418
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. FGF7-FGFR2 autocrine signaling increases growth and chemoresistance of fusion-positive rhabdomyosarcomas.
    Milton CI; Selfe J; Aladowicz E; Man SYK; Bernauer C; Missiaglia E; Walters ZS; Gatz SA; Kelsey A; Generali M; Box G; Valenti M; de Haven-Brandon A; Galiwango D; Hayes A; Clarke M; Izquierdo E; Gonzalez De Castro D; Raynaud FI; Kirkin V; Shipley JM
    Mol Oncol; 2022 Mar; 16(6):1272-1289. PubMed ID: 34850536
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Deciphering the Genomic Landscape and Pharmacological Profile of Uncommon Entities of Adult Rhabdomyosarcomas.
    De Vita A; Vanni S; Fausti V; Cocchi C; Recine F; Miserocchi G; Liverani C; Spadazzi C; Bassi M; Gessaroli M; Campobassi A; De Luca G; Pieri F; Farnedi A; Franchini E; Ferrari A; Domizio C; Cavagna E; Gurrieri L; Bongiovanni A; Riva N; Calpona S; Di Menna G; Debonis SA; Ibrahim T; Mercatali L
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768995
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma.
    Kim J; Light N; Subasri V; Young EL; Wegman-Ostrosky T; Barkauskas DA; Hall D; Lupo PJ; Patidar R; Maese LD; Jones K; Wang M; Tavtigian SV; Wu D; Shlien A; Telfer F; Goldenberg A; Skapek SX; Wei JS; Wen X; Catchpoole D; Hawkins DS; Schiffman JD; Khan J; Malkin D; Stewart DR
    JCO Precis Oncol; 2021; 5():. PubMed ID: 34095712
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Infantile Rhabdomyosarcomas With VGLL2 Rearrangement Are Not Always an Indolent Disease: A Study of 4 Aggressive Cases With Clinical, Pathologic, Molecular, and Radiologic Findings.
    Cyrta J; Gauthier A; Karanian M; Vieira AF; Cardoen L; Jehanno N; Bouvet M; Bouvier C; Komuta M; Le Loarer F; Orbach D; Rome A; Minard-Colin V; Brichard B; Pluchart C; Thebaud E; Renard M; Pannier S; Brisse H; Petit P; Benoist C; Schleiermacher G; Geoerger B; Vincent-Salomon A; Fréneaux P; Pierron G
    Am J Surg Pathol; 2021 Jun; 45(6):854-867. PubMed ID: 33949344
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor.
    Slotkin EK; Bowman AS; Levine MF; Dela Cruz F; Coutinho DF; Sanchez GI; Rosales N; Modak S; Tap WD; Gounder MM; Thornton KA; Bouvier N; You D; Gundem G; Gerstle JT; Heaton TE; LaQuaglia MP; Wexler LH; Meyers PA; Kung AL; Papaemmanuil E; Zehir A; Ladanyi M; Shukla N
    Mol Cancer Res; 2021 Jul; 19(7):1146-1155. PubMed ID: 33753552
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. fgfr4 promotes nuclear localization of GABP to inhibit cell apoptosis in uterine leiomyosarcoma.
    Zhang P; Zhang H; Wang Y
    Cell Tissue Res; 2021 Feb; 383(2):865-879. PubMed ID: 33151453
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group.
    Hingorani P; Dinu V; Zhang X; Lei H; Shern JF; Park J; Steel J; Rauf F; Parham D; Gastier-Foster J; Hall D; Hawkins DS; Skapek SX; Labaer J; McEachron TA
    Sci Rep; 2020 Jul; 10(1):12318. PubMed ID: 32703985
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma.
    Crawford KA; Berlow NE; Tsay J; Lazich M; Mancini M; Noakes C; Huang T; Keller C
    Cold Spring Harb Mol Case Stud; 2020 Jun; 6(3):. PubMed ID: 32532875
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Molecular mechanisms of Guadecitabine induced fgfr4 down regulation in alveolar rhabdomyosarcomas.
    Darvishi E; Slemmons K; Wan Z; Mitra S; Hou X; Hugues Parmentier J; Eddie Loh YH; Helman LJ
    Neoplasia; 2020 Jul; 22(7):274-282. PubMed ID: 32464274
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Recurrent secondary genomic alterations in desmoplastic small round cell tumors.
    Chow WA; Yee JK; Tsark W; Wu X; Qin H; Guan M; Ross JS; Ali SM; Millis SZ
    BMC Med Genet; 2020 May; 21(1):101. PubMed ID: 32393201
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Signaling pathways in Rhabdomyosarcoma invasion and metastasis.
    Ramadan F; Fahs A; Ghayad SE; Saab R
    Cancer Metastasis Rev; 2020 Mar; 39(1):287-301. PubMed ID: 31989508
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Insight into ponatinib resistance mechanisms in rhabdomyosarcoma caused by the mutations in fgfr4 tyrosine kinase using molecular modeling strategies.
    Wu C; Chen X; Chen D; Xia Q; Liu Z; Li F; Yan Y; Cai Y
    Int J Biol Macromol; 2019 Aug; 135():294-302. PubMed ID: 31128178
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The differential diagnoses of uterine leiomyomas and leiomyosarcomas using DNA and RNA sequencing.
    Mas A; Alonso R; Garrido-Gómez T; Escorcia P; Montero B; Jiménez-Almazán J; Martín J; Pellicer N; Monleón J; Simón C
    Am J Obstet Gynecol; 2019 Oct; 221(4):320.e1-320.e23. PubMed ID: 31121144
    [TBL] [Abstract] [Full Text] [Related]  


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