Terms: = Sarcomas AND FH, HLRCC, 2271, ENSG00000091483, MCUL1, MCL, LRCC, P07954 AND Treatment
66 results:
1. Regulation of the P53 tumor suppressor gene and the mcl-2 oncogene expression by an active herbal component delivered through a smart thermo-pH-sensitive PLGA carrier to improve Osteosarcoma treatment.
Akbari P; Taebpour M; Akhlaghi M; Hasan SH; Shahriyari S; Parsaeian M; Haghirosadat BF; Rahdar A; Pandey S
Med Oncol; 2024 Jan; 41(3):68. PubMed ID: 38289404
[TBL] [Abstract] [Full Text] [Related]
2. Advanced systemic mastocytosis-Revised classification, new drugs and how we treat.
Pardanani A; Reichard K; Tefferi A
Br J Haematol; 2024 Feb; 204(2):402-414. PubMed ID: 38054381
[TBL] [Abstract] [Full Text] [Related]
3. Bcl-xL is required to protect endothelial cells latently infected with KSHV from virus induced intrinsic apoptosis.
Moore LN; Holmes DL; Sharma A; Landazuri Vinueza J; Lagunoff M
PLoS Pathog; 2023 May; 19(5):e1011385. PubMed ID: 37163552
[TBL] [Abstract] [Full Text] [Related]
4. Low Bcl-2 is a robust biomarker of sensitivity to nab-paclitaxel in Ewing sarcoma.
Pascual-Pasto G; Resa-Pares C; Castillo-Ecija H; Aschero R; Baulenas-Farres M; Vila-Ubach M; Burgueño V; Balaguer-Lluna L; Cuadrado-Vilanova M; Olaciregui NG; Martinez-Velasco N; Perez-Jaume S; de Alava E; Tirado OM; Lavarino C; Mora J; Carcaboso AM
Biochem Pharmacol; 2023 Feb; 208():115408. PubMed ID: 36603685
[TBL] [Abstract] [Full Text] [Related]
5. Chidamide augment sorafenib-derived anti-tumor activities in human osteosarcoma cells lines and xenograft mouse model.
Yuan Y; Li D; Hu X; Li Y; Yi W; Li P; Zhao Y; Li Z; Yu A; Jian C; Yu A
Med Oncol; 2022 Apr; 39(5):87. PubMed ID: 35478053
[TBL] [Abstract] [Full Text] [Related]
6. Asiatic Acid Induces Mitochondrial Apoptosis via Inhibition of JAK2/STAT3 Signalling Pathway in Human Osteosarcoma.
Yan BF; Chen X; Liu J; Liu SJ; Zhang JZ; Zeng QQ; Duan JA
Folia Biol (Praha); 2021; 67(3):108-117. PubMed ID: 35151244
[TBL] [Abstract] [Full Text] [Related]
7. Selective BH3 mimetics synergize with BET inhibition to induce mitochondrial apoptosis in rhabdomyosarcoma cells.
Erdogdu U; Dolgikh N; Laszig S; Särchen V; Meister MT; Wanior M; Knapp S; Boedicker C
Neoplasia; 2022 Feb; 24(2):109-119. PubMed ID: 34959030
[TBL] [Abstract] [Full Text] [Related]
8. A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/mcl-1 balance as target for re-sensitization to first-line therapy in recurrent tumors.
Manzella G; Moonamale DC; Römmele M; Bode P; Wachtel M; Schäfer BW
Neoplasia; 2021 Sep; 23(9):929-938. PubMed ID: 34329950
[TBL] [Abstract] [Full Text] [Related]
9. [Multicenter clinical study on the diagnosis and treatment of childhood renal tumor].
Zhang AA; Tang JY; Xu M; Fang YJ; Yan J; Gao J; Yuan XJ; Li F; Ju XL; Liu W; Wu XJ; Sun LR; Jiang L; Zhang WL; Chu JH; Lu XY
Zhonghua Er Ke Za Zhi; 2021 Mar; 59(3):195-200. PubMed ID: 33657693
[No Abstract] [Full Text] [Related]
10. Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of mcl-1 by targeting FBW7.
Kim YJ; Kim Y; Kumar A; Kim CW; Toth Z; Cho NH; Lee HR
PLoS Pathog; 2021 Jan; 17(1):e1009179. PubMed ID: 33471866
[TBL] [Abstract] [Full Text] [Related]
11. Resistance of osteosarcoma cells to the proapoptotic effects of carfilzomib involves activation of mitogen activated protein kinase pathways.
Lei L; Zhang Y; Jian Q; Lei L; Lv N; Williamson RA; Chen P; Zhang D; Hu J
Exp Physiol; 2021 Feb; 106(2):438-449. PubMed ID: 33336554
[TBL] [Abstract] [Full Text] [Related]
12. Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer.
Scherr AL; Mock A; Gdynia G; Schmitt N; Heilig CE; Korell F; Rhadakrishnan P; Hoffmeister P; Metzeler KH; Schulze-Osthoff K; Illert AL; Boerries M; Trojan J; Waidmann O; Falkenhorst J; Siveke J; Jost PJ; Bitzer M; Malek NP; Vecchione L; Jelas I; Brors B; Glimm H; Stenzinger A; Grekova SP; Gehrig T; Schulze-Bergkamen H; Jäger D; Schirmacher P; Heikenwalder M; Goeppert B; Schneider M; Fröhling S; Köhler BC
Cell Death Dis; 2020 Oct; 11(10):875. PubMed ID: 33070156
[TBL] [Abstract] [Full Text] [Related]
13. The BCL-2 selective inhibitor ABT-199 sensitizes soft tissue sarcomas to proteasome inhibition by a concerted mechanism requiring BAX and NOXA.
Muenchow A; Weller S; Hinterleitner C; Malenke E; Bugl S; Wirths S; Müller MR; Schulze-Osthoff K; Aulitzky WE; Kopp HG; Essmann F
Cell Death Dis; 2020 Aug; 11(8):701. PubMed ID: 32839432
[TBL] [Abstract] [Full Text] [Related]
14. Differential mechanisms involved in RG-7388 and Nutlin-3 induced cell death in SJSA-1 osteosarcoma cells.
Natarajan U; Venkatesan T; Dhandayuthapani S; Dondapatti P; Rathinavelu A
Cell Signal; 2020 Nov; 75():109742. PubMed ID: 32827690
[TBL] [Abstract] [Full Text] [Related]
15. Sequential combinations of chemotherapeutic agents with BH3 mimetics to treat rhabdomyosarcoma and avoid resistance.
Alcon C; Manzano-Muñoz A; Prada E; Mora J; Soriano A; Guillén G; Gallego S; Roma J; Samitier J; Villanueva A; Montero J
Cell Death Dis; 2020 Aug; 11(8):634. PubMed ID: 32801295
[TBL] [Abstract] [Full Text] [Related]
16. Co-inhibition of BET proteins and PI3Kα triggers mitochondrial apoptosis in rhabdomyosarcoma cells.
Boedicker C; Hussong M; Grimm C; Dolgikh N; Meister MT; Enßle JC; Wanior M; Knapp S; Schweiger MR; Fulda S
Oncogene; 2020 May; 39(19):3837-3852. PubMed ID: 32161312
[TBL] [Abstract] [Full Text] [Related]
17. Targeting BCL-2 proteins in pediatric cancer: Dual inhibition of BCL-X
Kehr S; Haydn T; Bierbrauer A; Irmer B; Vogler M; Fulda S
Cancer Lett; 2020 Jul; 482():19-32. PubMed ID: 32145345
[TBL] [Abstract] [Full Text] [Related]
18. Licochalcone A-Induced Apoptosis Through the Activation of p38MAPK Pathway Mediated Mitochondrial Pathways of Apoptosis in Human Osteosarcoma Cells In Vitro and In Vivo.
Lin RC; Yang SF; Chiou HL; Hsieh SC; Wen SH; Lu KH; Hsieh YH
Cells; 2019 Nov; 8(11):. PubMed ID: 31739642
[TBL] [Abstract] [Full Text] [Related]
19. Limb Salvage Using Non-hinged Endoprosthesis and Staged Correction of Leg-length Discrepancy for Children with Distal Femoral Malignant Tumors.
Ji T; Yang Y; Li DS; Tang XD; Guo W
Orthop Surg; 2019 Oct; 11(5):819-825. PubMed ID: 31489784
[TBL] [Abstract] [Full Text] [Related]
20. Loss of PDPK1 abrogates resistance to gemcitabine in label-retaining pancreatic cancer cells.
Li D; Mullinax JE; Aiken T; Xin H; Wiegand G; Anderson A; Thorgeirsson S; Avital I; Rudloff U
BMC Cancer; 2018 Jul; 18(1):772. PubMed ID: 30064387
[TBL] [Abstract] [Full Text] [Related]
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