Terms: = Sarcomas AND HEY1, CHF-2, 23462, ENSG00000164683, HESR1, CHF2, HESR-1, MGC1274, HRT-1, OAF1, HERP2 AND Treatment
15 results:
1. Construction of a transcription factor-miRNA-mRNA interactive network elucidates underlying pathogenesis for osteosarcoma and validation by qRT-PCR.
Tang F; Jiang X; Liao S; Liu Y; He M
Medicine (Baltimore); 2022 Oct; 101(41):e31049. PubMed ID: 36254052
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2. Patient-derived xenografts and in vitro model show rationale for imatinib mesylate repurposing in hey1-NCoA2-driven mesenchymal chondrosarcoma.
Safaric Tepes P; Segovia D; Jevtic S; Ramirez D; Lyons SK; Sordella R
Lab Invest; 2022 Sep; 102(9):1038-1049. PubMed ID: 34837064
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3. Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Yang J; Hu Y; Wang L; Sun X; Yu L; Guo W
Bioengineered; 2021 Dec; 12(2):11007-11017. PubMed ID: 34781817
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4. Primary intradural extramedullary spinal mesenchymal chondrosarcoma: case report and literature review.
Chen CW; Chen IH; Hu MH; Lee JC; Huang HY; Hong RL; Yang SH
BMC Musculoskelet Disord; 2019 Sep; 20(1):408. PubMed ID: 31484514
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5. Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling.
Cao Y; Yu L; Dai G; Zhang S; Zhang Z; Gao T; Guo W
Eur J Pharmacol; 2017 Jan; 794():77-84. PubMed ID: 27845066
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6. Inhibition of Bcl-2 family members sensitizes mesenchymal chondrosarcoma to conventional chemotherapy: report on a novel mesenchymal chondrosarcoma cell line.
de Jong Y; van Maldegem AM; Marino-Enriquez A; de Jong D; Suijker J; Briaire-de Bruijn IH; Kruisselbrink AB; Cleton-Jansen AM; Szuhai K; Gelderblom H; Fletcher JA; Bovée JV
Lab Invest; 2016 Oct; 96(10):1128-37. PubMed ID: 27617402
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7. Doxorubicin Inhibits Proliferation of Osteosarcoma Cells Through Upregulation of the Notch Signaling Pathway.
Ji P; Yu L; Guo WC; Mei HJ; Wang XJ; Chen H; Fang S; Yang J
Oncol Res; 2014; 22(4):185-191. PubMed ID: 26351207
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8. Intraparenchymal mesenchymal chondrosarcoma of the frontal lobe--a case report and molecular detection of specific gene fusions from archival FFPE sample.
Sajjad EA; Sikora K; Paciejewski T; Garbicz F; Paskal W; Szacht M; Grajkowska W; Włodarski PK
Clin Neuropathol; 2015; 34(5):288-93. PubMed ID: 25907264
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9. Suppression of deacetylase SIRT1 mediates tumor-suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcoma.
Ban J; Aryee DN; Fourtouna A; van der Ent W; Kauer M; Niedan S; Machado I; Rodriguez-Galindo C; Tirado OM; Schwentner R; Picci P; Flanagan AM; Berg V; Strauss SJ; Scotlandi K; Lawlor ER; Snaar-Jagalska E; Llombart-Bosch A; Kovar H
Cancer Res; 2014 Nov; 74(22):6578-88. PubMed ID: 25281719
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10. Latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus promotes angiogenesis through targeting notch signaling effector hey1.
Wang X; He Z; Xia T; Li X; Liang D; Lin X; Wen H; Lan K
Cancer Res; 2014 Apr; 74(7):2026-37. PubMed ID: 24523441
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11. HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors.
Dailey DD; Anfinsen KP; Pfaff LE; Ehrhart EJ; Charles JB; Bønsdorff TB; Thamm DH; Powers BE; Jonasdottir TJ; Duval DL
BMC Vet Res; 2013 Jul; 9():130. PubMed ID: 23816051
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12. Inhibition of the Notch-hey1 axis blocks embryonal rhabdomyosarcoma tumorigenesis.
Belyea BC; Naini S; Bentley RC; Linardic CM
Clin Cancer Res; 2011 Dec; 17(23):7324-36. PubMed ID: 21948088
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13. Sclerostin expression is induced by BMPs in human Saos-2 osteosarcoma cells but not via direct effects on the sclerostin gene promoter or ECR5 element.
Yu L; van der Valk M; Cao J; Han CY; Juan T; Bass MB; Deshpande C; Damore MA; Stanton R; Babij P
Bone; 2011 Dec; 49(6):1131-40. PubMed ID: 21890009
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14. Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation.
Tanaka M; Setoguchi T; Hirotsu M; Gao H; Sasaki H; Matsunoshita Y; Komiya S
Br J Cancer; 2009 Jun; 100(12):1957-65. PubMed ID: 19455146
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15. Notch signaling contributes to the pathogenesis of human osteosarcomas.
Engin F; Bertin T; Ma O; Jiang MM; Wang L; Sutton RE; Donehower LA; Lee B
Hum Mol Genet; 2009 Apr; 18(8):1464-70. PubMed ID: 19228774
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