Terms: = Sarcomas AND HIF1A, Q16665, 3091, ENSG00000100644, MOP1, HIF1-ALPHA, PASD8, HIF-1alpha AND Treatment
79 results:
1. Phase I study of sapanisertib (CB-228/TAK-228/MLN0128) in combination with ziv-aflibercept in patients with advanced solid tumors.
Coleman N; Stephen B; Fu S; Karp D; Subbiah V; Ahnert JR; Piha-Paul SA; Wright J; Fessahaye SN; Ouyang F; Yilmaz B; Meric-Bernstam F; Naing A
Cancer Med; 2024 Feb; 13(3):e6877. PubMed ID: 38400671
[TBL] [Abstract] [Full Text] [Related]
2. FT895 Impairs Mitochondrial Function in Malignant Peripheral Nerve Sheath Tumor Cells.
Huang PY; Shih IA; Liao YC; You HL; Lee MJ
Int J Mol Sci; 2023 Dec; 25(1):. PubMed ID: 38203448
[TBL] [Abstract] [Full Text] [Related]
3. PDGFRβ Signaling Cooperates with β-Catenin to Modulate c-Abl and Biologic Behavior of Desmoid-Type Fibromatosis.
Hu J; Hameed MR; Agaram NP; Whiting KA; Qin LX; Villano AM; O'Connor RB; Rozenberg JM; Cohen S; Prendergast K; Kryeziu S; White RL; Posner MC; Socci ND; Gounder MM; Singer S; Crago AM
Clin Cancer Res; 2024 Jan; 30(2):450-461. PubMed ID: 37943631
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4. Network Pharmacology-Based Identification of Key Pharmacological Mechanism of Shen-qi-di-huang Decoction Acting on Uremia.
Zhang X; Chen XF; Chen WJ; Ding H; Zhang BX
Altern Ther Health Med; 2024 Jan; 30(1):44-50. PubMed ID: 37773677
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5. Synergistic anti-tumour activity of ginsenoside Rg3 and doxorubicin on proliferation, metastasis and angiogenesis in osteosarcoma by modulating mTOR/HIF-1α/VEGF and EMT signalling pathways.
Zeng X; Liu S; Yang H; Jia M; Liu W; Zhu W
J Pharm Pharmacol; 2023 Nov; 75(11):1405-1417. PubMed ID: 37498992
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6. HIF-1α/MMP-9 promotes spinal cord central sensitization in rats with bone cancer pain.
Yang L; Fu Q; Yang L; Zhang Y
Eur J Pharmacol; 2023 Sep; 954():175858. PubMed ID: 37356787
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7. Hypoxia Inhibitor Combined with Chemotherapeutic Agents for Antitumor and Antimetastatic Efficacy against Osteosarcoma.
Zhao TT; Zhou TJ; Zhang C; Liu YX; Wang WJ; Li C; Xing L; Jiang HL
Mol Pharm; 2023 May; 20(5):2612-2623. PubMed ID: 37042832
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8. Hypoxia and HIFs in Ewing sarcoma: new perspectives on a multi-facetted relationship.
Ceranski AK; Carreño-Gonzalez MJ; Ehlers AC; Colombo MV; Cidre-Aranaz F; Grünewald TGP
Mol Cancer; 2023 Mar; 22(1):49. PubMed ID: 36915100
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9. Based on network pharmacology and bioinformatics to analyze the mechanism of action of Astragalus membranaceus in the treatment of vitiligo and COVID-19.
Wang Y; Ding M; Chi J; Wang T; Zhang Y; Li Z; Li Q
Sci Rep; 2023 Mar; 13(1):3884. PubMed ID: 36890149
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10. Activation of PGRN/MAPK axis stimulated by the hypoxia-conditioned mesenchymal stem cell-derived HIF-1α facilitates osteosarcoma progression.
Shang C; Ou X; Zhang H; Wei D; Wang Q; Li G
Exp Cell Res; 2022 Dec; 421(1):113373. PubMed ID: 36183781
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11. HIF-1α-mediated augmentation of miRNA-18b-5p facilitates proliferation and metastasis in osteosarcoma through attenuation PHF2.
Luo P; Zhang YD; He F; Tong CJ; Liu K; Liu H; Zhu SZ; Luo JZ; Yuan B
Sci Rep; 2022 Jun; 12(1):10398. PubMed ID: 35729160
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12. IDH1 Mutation Induces HIF-1
Hu X; Li L; Eid JE; Liu C; Yu J; Yue J; Trent JC
Dis Markers; 2022; 2022():7729968. PubMed ID: 35198082
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13. CCL4 Stimulates Cell Migration in Human Osteosarcoma via the mir-3927-3p/Integrin αvβ3 Axis.
Tsai HC; Lai YY; Hsu HC; Fong YC; Lien MY; Tang CH
Int J Mol Sci; 2021 Nov; 22(23):. PubMed ID: 34884541
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14. Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity.
von Fallois M; Kosyna FK; Mandl M; Landesman Y; Dunst J; Depping R
J Cancer Res Clin Oncol; 2021 Jul; 147(7):2025-2033. PubMed ID: 33856525
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15. Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Gampala S; Shah F; Zhang C; Rhodes SD; Babb O; Grimard M; Wireman RS; Rad E; Calver B; Bai RY; Staedtke V; Hulsey EL; Saadatzadeh MR; Pollok KE; Tong Y; Smith AE; Clapp DW; Tee AR; Kelley MR; Fishel ML
Br J Cancer; 2021 Apr; 124(9):1566-1580. PubMed ID: 33658640
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16. Sauchinone inhibits hypoxia-induced invasion and epithelial-mesenchymal transition in osteosarcoma cells via inactivation of the sonic hedgehog pathway.
Zhou D; He L
J Recept Signal Transduct Res; 2022 Apr; 42(2):173-179. PubMed ID: 33563062
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17. The impact of tumor fragmentation in patients with stage I uterine leiomyosarcoma on patterns of recurrence and oncologic outcome.
Pedra Nobre S; Hensley ML; So M; Zhou QC; Iasonos A; Leitao MM; Ducie J; Chiang S; Mueller JJ; Abu-Rustum NR; Zivanovic O
Gynecol Oncol; 2021 Jan; 160(1):99-105. PubMed ID: 33158511
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18. HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
He G; Pan X; Liu X; Zhu Y; Ma Y; Du C; Liu X; Mao C
ACS Appl Mater Interfaces; 2020 Oct; 12(43):48296-48309. PubMed ID: 33054172
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19. VS-5584 Inhibits Human Osteosarcoma Cells Growth by Induction of G1- phase Arrest through Regulating PI3K/mTOR and MAPK Pathways.
Sun JY; Hou YJ; Cui HJ; Zhang C; Yang MF; Wang FZ; Sun Z; Fan CD; Sun BL; Oh JR
Curr Cancer Drug Targets; 2020; 20(8):616-623. PubMed ID: 32286946
[TBL] [Abstract] [Full Text] [Related]
20. Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential treatment Applications.
Sun W; Wang B; Qu XL; Zheng BQ; Huang WD; Sun ZW; Wang CM; Chen Y
Cells; 2019 Dec; 9(1):. PubMed ID: 31905813
[TBL] [Abstract] [Full Text] [Related]
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