Terms: = Sarcomas AND IRF4, LSIRF, 3662, ENSG00000137265, Q15306
20 results:
1. Druggable host gene dependencies in primary effusion lymphoma.
Kuehnle N; Gottwein E
Curr Opin Virol; 2022 Oct; 56():101270. PubMed ID: 36182745
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2. MUM1/irf4 is Highly Expressed in Dermatopathic Lymphadenopathy: Potential Utility in Diagnosis and Differential Diagnosis.
Garces S; Rudzki Z; Yin CC; Miranda RN; Medina AM; Sriganeshan V; Cuglievan B; Li S; Xu J; Jelloul F; Khoury JD; Thakral B; Tang G; Garces JC; Medeiros LJ
Am J Surg Pathol; 2022 Nov; 46(11):1514-1523. PubMed ID: 35877199
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3. Proximity Biotin Labeling Reveals Kaposi's Sarcoma-Associated Herpesvirus Interferon Regulatory Factor Networks.
Kumar A; Salemi M; Bhullar R; Guevara-Plunkett S; Lyu Y; Wang KH; Izumiya C; Campbell M; Nakajima KI; Izumiya Y
J Virol; 2021 Apr; 95(9):. PubMed ID: 33597212
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4. Pomalidomide restores immune recognition of primary effusion lymphoma through upregulation of ICAM-1 and B7-2.
Shrestha P; Davis DA; Jaeger HK; Stream A; Aisabor AI; Yarchoan R
PLoS Pathog; 2021 Jan; 17(1):e1009091. PubMed ID: 33411730
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5. Kaposi's Sarcoma-Associated Herpesvirus Drives a Super-Enhancer-Mediated Survival Gene Expression Program in Primary Effusion Lymphoma.
Manzano M; Günther T; Ju H; Nicholas J; Bartom ET; Grundhoff A; Gottwein E
mBio; 2020 Aug; 11(4):. PubMed ID: 32843547
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6. Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional
Park A; Oh S; Jung KL; Choi UY; Lee HR; Rosenfeld MG; Jung JU
Proc Natl Acad Sci U S A; 2020 Sep; 117(35):21618-21627. PubMed ID: 32817485
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7. Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression.
Devalaraja S; To TKJ; Folkert IW; Natesan R; Alam MZ; Li M; Tada Y; Budagyan K; Dang MT; Zhai L; Lobel GP; Ciotti GE; Eisinger-Mathason TSK; Asangani IA; Weber K; Simon MC; Haldar M
Cell; 2020 Mar; 180(6):1098-1114.e16. PubMed ID: 32169218
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8. Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma.
Manzano M; Patil A; Waldrop A; Dave SS; Behdad A; Gottwein E
Nat Commun; 2018 Aug; 9(1):3263. PubMed ID: 30111820
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9. Wnt/β-Catenin Signaling Activates Expression of the Bone-Related Transcription Factor RUNX2 in Select Human Osteosarcoma Cell Types.
Vega OA; Lucero CMJ; Araya HF; Jerez S; Tapia JC; Antonelli M; Salazar-Onfray F; Las Heras F; Thaler R; Riester SM; Stein GS; van Wijnen AJ; Galindo MA
J Cell Biochem; 2017 Nov; 118(11):3662-3674. PubMed ID: 28370561
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10. Genomic landscape of endometrial stromal sarcoma of uterus.
Choi YJ; Jung SH; Kim MS; Baek IP; Rhee JK; Lee SH; Hur SY; Kim TM; Chung YJ; Lee SH
Oncotarget; 2015 Oct; 6(32):33319-28. PubMed ID: 26429873
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11. Immunomodulatory drugs target IKZF1-irf4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors.
Gopalakrishnan R; Matta H; Tolani B; Triche T; Chaudhary PM
Oncogene; 2016 Apr; 35(14):1797-810. PubMed ID: 26119939
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12. Downregulation of irf4 induces lytic reactivation of KSHV in primary effusion lymphoma cells.
Forero A; McCormick KD; Jenkins FJ; Sarkar SN
Virology; 2014 Jun; 458-459():4-10. PubMed ID: 24928034
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13. Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (virf4) targets expression of cellular irf4 and the Myc gene to facilitate lytic replication.
Lee HR; Doğanay S; Chung B; Toth Z; Brulois K; Lee S; Kanketayeva Z; Feng P; Ha T; Jung JU
J Virol; 2014 Feb; 88(4):2183-94. PubMed ID: 24335298
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14. IRF-4-mediated CIITA transcription is blocked by KSHV encoded LANA to inhibit MHC II presentation.
Cai Q; Banerjee S; Cervini A; Lu J; Hislop AD; Dzeng R; Robertson ES
PLoS Pathog; 2013 Oct; 9(10):e1003751. PubMed ID: 24204280
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15. Role of irf4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells.
Forero A; Moore PS; Sarkar SN
J Immunol; 2013 Aug; 191(3):1476-85. PubMed ID: 23804715
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16. Kaposi's sarcoma-associated herpesvirus noncoding polyadenylated nuclear RNA interacts with virus- and host cell-encoded proteins and suppresses expression of genes involved in immune modulation.
Rossetto CC; Pari GS
J Virol; 2011 Dec; 85(24):13290-7. PubMed ID: 21957289
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17. HHV8-positive, EBV-positive Hodgkin lymphoma-like large B-cell lymphoma and HHV8-positive intravascular large B-cell lymphoma.
Ferry JA; Sohani AR; Longtine JA; Schwartz RA; Harris NL
Mod Pathol; 2009 May; 22(5):618-26. PubMed ID: 19287457
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18. Immunophenotypic analysis of the Kaposi sarcoma herpesvirus (KSHV; HHV-8)-infected B cells in HIV+ multicentric Castleman disease (MCD).
Chadburn A; Hyjek EM; Tam W; Liu Y; Rengifo T; Cesarman E; Knowles DM
Histopathology; 2008 Nov; 53(5):513-24. PubMed ID: 18983461
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19. Potential cellular signatures of viral infections in human hematopoietic cells.
Mikovits J; Ruscetti F; Zhu W; Bagni R; Dorjsuren D; Shoemaker R
Dis Markers; 2001; 17(3):173-8. PubMed ID: 11790884
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20. Expression of MUM1/irf4 selectively clusters with primary effusion lymphoma among lymphomatous effusions: implications for disease histogenesis and pathogenesis.
Carbone A; Gloghini A; Cozzi MR; Capello D; Steffan A; Monini P; De Marco L; Gaidano G
Br J Haematol; 2000 Oct; 111(1):247-57. PubMed ID: 11091208
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