Terms: = Sarcomas AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132
18 results:
1. A tumor suppressor protein encoded by circkeap1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity.
Zhang Y; Liu Z; Zhong Z; Ji Y; Guo H; Wang W; Chen C
J Exp Clin Cancer Res; 2024 Feb; 43(1):52. PubMed ID: 38383479
[TBL] [Abstract] [Full Text] [Related]
2. DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting keap1-Mediated NRF2 Ubiquitination.
Wang X; Zhou T; Yang X; Cao X; Jin G; Zhang P; Guo J; Rong K; Li B; Hu Y; Liu K; Ma P; Qin A; Zhao J
Adv Sci (Weinh); 2023 May; 10(14):e2204438. PubMed ID: 36965071
[TBL] [Abstract] [Full Text] [Related]
3. TRIM22 inhibits osteosarcoma progression through destabilizing NRF2 and thus activation of ROS/AMPK/mTOR/autophagy signaling.
Liu W; Zhao Y; Wang G; Feng S; Ge X; Ye W; Wang Z; Zhu Y; Cai W; Bai J; Zhou X
Redox Biol; 2022 Jul; 53():102344. PubMed ID: 35636015
[TBL] [Abstract] [Full Text] [Related]
4. The prevalence and real-world therapeutic analysis of Chinese patients with KRAS-Mutant Non-Small Cell lung cancer.
Chen H; Huang D; Lin G; Yang X; Zhuo M; Chi Y; Zhai X; Jia B; Wang J; Wang Y; Li J; An T; Wu M; Wang Z; Zhao J
Cancer Med; 2022 Oct; 11(19):3581-3592. PubMed ID: 35394121
[TBL] [Abstract] [Full Text] [Related]
5. LAMTOR5-AS1 regulates chemotherapy-induced oxidative stress by controlling the expression level and transcriptional activity of NRF2 in osteosarcoma cells.
Pu Y; Tan Y; Zang C; Zhao F; Cai C; Kong L; Deng H; Chao F; Xia R; Xie M; Ge F; Pan Y; Cai S; Huang D
Cell Death Dis; 2021 Dec; 12(12):1125. PubMed ID: 34862368
[TBL] [Abstract] [Full Text] [Related]
6. Sotorasib for Lung Cancers with
Skoulidis F; Li BT; Dy GK; Price TJ; Falchook GS; Wolf J; Italiano A; Schuler M; Borghaei H; Barlesi F; Kato T; Curioni-Fontecedro A; Sacher A; Spira A; Ramalingam SS; Takahashi T; Besse B; Anderson A; Ang A; Tran Q; Mather O; Henary H; Ngarmchamnanrith G; Friberg G; Velcheti V; Govindan R
N Engl J Med; 2021 Jun; 384(25):2371-2381. PubMed ID: 34096690
[TBL] [Abstract] [Full Text] [Related]
7. Genetic and clonal dissection of osteosarcoma progression and lung metastasis.
Xu H; Zhu X; Bao H; Wh Shek T; Huang Z; Wang Y; Wu X; Wu Y; Chang Z; Wu S; Tang Q; Zhang H; Han A; Mc Cheung K; Zou C; Yau R; Ho WY; Huang G; Batalha S; Lu J; Song G; Kang Y; Shao YW; Lam YL; Shen J; Wang J
Int J Cancer; 2018 Sep; 143(5):1134-1142. PubMed ID: 29569716
[TBL] [Abstract] [Full Text] [Related]
8. Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice.
Chartoumpekis DV; Yagishita Y; Fazzari M; Palliyaguru DL; Rao UN; Zaravinos A; Khoo NK; Schopfer FJ; Weiss KR; Michalopoulos GK; Sipula I; O'Doherty RM; Kensler TW; Wakabayashi N
JCI Insight; 2018 Mar; 3(5):. PubMed ID: 29515034
[TBL] [Abstract] [Full Text] [Related]
9. Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities.
Yoshida A; Kobayashi E; Kubo T; Kodaira M; Motoi T; Motoi N; Yonemori K; Ohe Y; Watanabe SI; Kawai A; Kohno T; Kishimoto H; Ichikawa H; Hiraoka N
Mod Pathol; 2017 Jun; 30(6):797-809. PubMed ID: 28256572
[TBL] [Abstract] [Full Text] [Related]
10. Expression of the Nrf2 and keap1 proteins and their clinical significance in osteosarcoma.
Zhang J; Wang X; Wu W; Dang H; Wang B
Biochem Biophys Res Commun; 2016 Apr; 473(1):42-46. PubMed ID: 26987716
[TBL] [Abstract] [Full Text] [Related]
11. Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention.
Harder B; Jiang T; Wu T; Tao S; Rojo de la Vega M; Tian W; Chapman E; Zhang DD
Biochem Soc Trans; 2015 Aug; 43(4):680-6. PubMed ID: 26551712
[TBL] [Abstract] [Full Text] [Related]
12. Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.
Wijdeven RH; Pang B; van der Zanden SY; Qiao X; Blomen V; Hoogstraat M; Lips EH; Janssen L; Wessels L; Brummelkamp TR; Neefjes J
Cancer Res; 2015 Oct; 75(19):4176-87. PubMed ID: 26260527
[TBL] [Abstract] [Full Text] [Related]
13. Kaposi's sarcoma-associated herpesvirus induces Nrf2 activation in latently infected endothelial cells through SQSTM1 phosphorylation and interaction with polyubiquitinated keap1.
Gjyshi O; Flaherty S; Veettil MV; Johnson KE; Chandran B; Bottero V
J Virol; 2015 Feb; 89(4):2268-86. PubMed ID: 25505069
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14. Kaposi's sarcoma-associated herpesvirus induces Nrf2 during de novo infection of endothelial cells to create a microenvironment conducive to infection.
Gjyshi O; Bottero V; Veettil MV; Dutta S; Singh VV; Chikoti L; Chandran B
PLoS Pathog; 2014 Oct; 10(10):e1004460. PubMed ID: 25340789
[TBL] [Abstract] [Full Text] [Related]
15. LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT.
Kaufman JM; Amann JM; Park K; Arasada RR; Li H; Shyr Y; Carbone DP
J Thorac Oncol; 2014 Jun; 9(6):794-804. PubMed ID: 24828662
[TBL] [Abstract] [Full Text] [Related]
16. Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review.
Xu J; Zhang T; Wang T; You L; Zhao Y
World J Surg Oncol; 2013 Nov; 11():290. PubMed ID: 24219646
[TBL] [Abstract] [Full Text] [Related]
17. Mutational and expressional analyses of NRF2 and keap1 in sarcomas.
Je EM; An CH; Yoo NJ; Lee SH
Tumori; 2012; 98(4):510-5. PubMed ID: 23052169
[TBL] [Abstract] [Full Text] [Related]
18. The synthetic oleanane triterpenoid, CDDO-methyl ester, is a potent antiangiogenic agent.
Vannini N; Lorusso G; Cammarota R; Barberis M; Noonan DM; Sporn MB; Albini A
Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3139-46. PubMed ID: 18065492
[TBL] [Abstract] [Full Text] [Related]
