Terms: = Sarcomas AND KEAP1, INrf2, ENSG00000079999, 9817, Q14145, MGC9454, MGC4407, MGC20887, MGC1114, MGC10630, KLHL19, KIAA0132 AND Treatment
9 results:
1. A tumor suppressor protein encoded by circkeap1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity.
Zhang Y; Liu Z; Zhong Z; Ji Y; Guo H; Wang W; Chen C
J Exp Clin Cancer Res; 2024 Feb; 43(1):52. PubMed ID: 38383479
[TBL] [Abstract] [Full Text] [Related]
2. DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting keap1-Mediated NRF2 Ubiquitination.
Wang X; Zhou T; Yang X; Cao X; Jin G; Zhang P; Guo J; Rong K; Li B; Hu Y; Liu K; Ma P; Qin A; Zhao J
Adv Sci (Weinh); 2023 May; 10(14):e2204438. PubMed ID: 36965071
[TBL] [Abstract] [Full Text] [Related]
3. TRIM22 inhibits osteosarcoma progression through destabilizing NRF2 and thus activation of ROS/AMPK/mTOR/autophagy signaling.
Liu W; Zhao Y; Wang G; Feng S; Ge X; Ye W; Wang Z; Zhu Y; Cai W; Bai J; Zhou X
Redox Biol; 2022 Jul; 53():102344. PubMed ID: 35636015
[TBL] [Abstract] [Full Text] [Related]
4. The prevalence and real-world therapeutic analysis of Chinese patients with KRAS-Mutant Non-Small Cell lung cancer.
Chen H; Huang D; Lin G; Yang X; Zhuo M; Chi Y; Zhai X; Jia B; Wang J; Wang Y; Li J; An T; Wu M; Wang Z; Zhao J
Cancer Med; 2022 Oct; 11(19):3581-3592. PubMed ID: 35394121
[TBL] [Abstract] [Full Text] [Related]
5. Sotorasib for Lung Cancers with
Skoulidis F; Li BT; Dy GK; Price TJ; Falchook GS; Wolf J; Italiano A; Schuler M; Borghaei H; Barlesi F; Kato T; Curioni-Fontecedro A; Sacher A; Spira A; Ramalingam SS; Takahashi T; Besse B; Anderson A; Ang A; Tran Q; Mather O; Henary H; Ngarmchamnanrith G; Friberg G; Velcheti V; Govindan R
N Engl J Med; 2021 Jun; 384(25):2371-2381. PubMed ID: 34096690
[TBL] [Abstract] [Full Text] [Related]
6. Expression of the Nrf2 and keap1 proteins and their clinical significance in osteosarcoma.
Zhang J; Wang X; Wu W; Dang H; Wang B
Biochem Biophys Res Commun; 2016 Apr; 473(1):42-46. PubMed ID: 26987716
[TBL] [Abstract] [Full Text] [Related]
7. Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention.
Harder B; Jiang T; Wu T; Tao S; Rojo de la Vega M; Tian W; Chapman E; Zhang DD
Biochem Soc Trans; 2015 Aug; 43(4):680-6. PubMed ID: 26551712
[TBL] [Abstract] [Full Text] [Related]
8. Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.
Wijdeven RH; Pang B; van der Zanden SY; Qiao X; Blomen V; Hoogstraat M; Lips EH; Janssen L; Wessels L; Brummelkamp TR; Neefjes J
Cancer Res; 2015 Oct; 75(19):4176-87. PubMed ID: 26260527
[TBL] [Abstract] [Full Text] [Related]
9. LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT.
Kaufman JM; Amann JM; Park K; Arasada RR; Li H; Shyr Y; Carbone DP
J Thorac Oncol; 2014 Jun; 9(6):794-804. PubMed ID: 24828662
[TBL] [Abstract] [Full Text] [Related]
