Terms: = Sarcomas AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1
17 results:
1. Small-molecule inhibition of map2k4 is synergistic with RAS inhibitors in
Jansen RA; Mainardi S; Dias MH; Bosma A; van Dijk E; Selig R; Albrecht W; Laufer SA; Zender L; Bernards R
Proc Natl Acad Sci U S A; 2024 Feb; 121(9):e2319492121. PubMed ID: 38377196
[TBL] [Abstract] [Full Text] [Related]
2. Network Pharmacology-Based Identification of Key Pharmacological Mechanism of Shen-qi-di-huang Decoction Acting on Uremia.
Zhang X; Chen XF; Chen WJ; Ding H; Zhang BX
Altern Ther Health Med; 2024 Jan; 30(1):44-50. PubMed ID: 37773677
[TBL] [Abstract] [Full Text] [Related]
3. Uterine leiomyosarcomas harboring map2k4 gene amplification are sensitive in vivo to PLX8725, a novel map2k4 inhibitor.
McNamara B; Harold J; Manavella D; Bellone S; Mutlu L; Hartwich TMP; Zipponi M; Yang-Hartwich Y; Demirkiran C; Verzosa MSZ; Yang K; Choi J; Dong W; Buza N; Hui P; Altwerger G; Huang GS; Andikyan V; Clark M; Ratner E; Azodi M; Schwartz PE; Burton EA; Inagaki H; Albers A; Zhang C; Bollag G; Schlessinger J; Santin AD
Gynecol Oncol; 2023 May; 172():65-71. PubMed ID: 36958197
[TBL] [Abstract] [Full Text] [Related]
4. Integrated mutational landscape analysis of uterine leiomyosarcomas.
Choi J; Manzano A; Dong W; Bellone S; Bonazzoli E; Zammataro L; Yao X; Deshpande A; Zaidi S; Guglielmi A; Gnutti B; Nagarkatti N; Tymon-Rosario JR; Harold J; Mauricio D; Zeybek B; Menderes G; Altwerger G; Jeong K; Zhao S; Buza N; Hui P; Ravaggi A; Bignotti E; Romani C; Todeschini P; Zanotti L; Odicino F; Pecorelli S; Ardighieri L; Bilguvar K; Quick CM; Silasi DA; Huang GS; Andikyan V; Clark M; Ratner E; Azodi M; Imielinski M; Schwartz PE; Alexandrov LB; Lifton RP; Schlessinger J; Santin AD
Proc Natl Acad Sci U S A; 2021 Apr; 118(15):. PubMed ID: 33876771
[TBL] [Abstract] [Full Text] [Related]
5. Sperm associated antigen 9 promotes oncogenic KSHV-encoded interferon regulatory factor-induced cellular transformation and angiogenesis by activating the JNK/VEGFA pathway.
Li W; Wang F; Shi J; Feng Q; Chen Y; Qi X; Wang C; Lu H; Lu Z; Jia X; Yan Q; Gao SJ; Lu C
PLoS Pathog; 2020 Aug; 16(8):e1008730. PubMed ID: 32776977
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6. Endocrine-responsive lobular carcinoma of the breast: features associated with risk of late distant recurrence.
Conforti F; Pala L; Pagan E; Viale G; Bagnardi V; Peruzzotti G; De Pas T; Bianco N; Graffeo R; Rocco EG; Vingiani A; Gelber RD; Coates AS; Colleoni M; Goldhirsch A
Breast Cancer Res; 2019 Dec; 21(1):153. PubMed ID: 31888717
[TBL] [Abstract] [Full Text] [Related]
7. Combined mTORC1/mTORC2 inhibition blocks growth and induces catastrophic macropinocytosis in cancer cells.
Srivastava RK; Li C; Khan J; Banerjee NS; Chow LT; Athar M
Proc Natl Acad Sci U S A; 2019 Dec; 116(49):24583-24592. PubMed ID: 31732667
[TBL] [Abstract] [Full Text] [Related]
8. Pulmonary carcinosarcoma: analysis from the Surveillance, Epidemiology and End Results database.
Sun L; Dai J; Wang X; Jiang G; Gonzalez-Rivas D; Song J; Zhang P
Interact Cardiovasc Thorac Surg; 2020 Jan; 30(1):4-10. PubMed ID: 31518405
[TBL] [Abstract] [Full Text] [Related]
9. Targetable Alterations in Adult Patients With Soft-Tissue sarcomas: Insights for Personalized Therapy.
Lucchesi C; Khalifa E; Laizet Y; Soubeyran I; Mathoulin-Pelissier S; Chomienne C; Italiano A
JAMA Oncol; 2018 Oct; 4(10):1398-1404. PubMed ID: 29801054
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10. Identification of predictors for wound complications following preoperative or postoperative radiotherapy in extremity soft tissue sarcoma.
Stevenson MG; Ubbels JF; Slump J; Huijing MA; Bastiaannet E; Pras E; Hoekstra HJ; Been LB
Eur J Surg Oncol; 2018 Jun; 44(6):816-822. PubMed ID: 29472042
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11. Molecular profiling of soft tissue sarcomas using next-generation sequencing: a pilot study toward precision therapeutics.
Jour G; Scarborough JD; Jones RL; Loggers E; Pollack SM; Pritchard CC; Hoch BL
Hum Pathol; 2014 Aug; 45(8):1563-71. PubMed ID: 24908143
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12. MicroRNA-27a promotes proliferation, migration and invasion by targeting map2k4 in human osteosarcoma cells.
Pan W; Wang H; Jianwei R; Ye Z
Cell Physiol Biochem; 2014; 33(2):402-12. PubMed ID: 24556602
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13. Differential gene expressions of the MAPK signaling pathway in enterovirus 71-infected rhabdomyosarcoma cells.
Shi W; Hou X; Li X; Peng H; Shi M; Jiang Q; Liu X; Ji Y; Yao Y; He C; Lei X
Braz J Infect Dis; 2013; 17(4):410-7. PubMed ID: 23797008
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14. MAPK7 and map2k4 as prognostic markers in osteosarcoma.
Tesser-Gamba F; Petrilli AS; de Seixas Alves MT; Filho RJ; Juliano Y; Toledo SR
Hum Pathol; 2012 Jul; 43(7):994-1002. PubMed ID: 22154052
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15. Genetic and molecular alterations in rhabdomyosarcoma: mRNA overexpression of MCL1 and map2k4 genes.
Pazzaglia L; Chiechi A; Conti A; Gamberi G; Magagnoli G; Novello C; Morandi L; Picci P; Mercuri M; Benassi MS
Histol Histopathol; 2009 Jan; 24(1):61-7. PubMed ID: 19012245
[TBL] [Abstract] [Full Text] [Related]
16. ORF36 protein kinase of Kaposi's sarcoma herpesvirus activates the c-Jun N-terminal kinase signaling pathway.
Hamza MS; Reyes RA; Izumiya Y; Wisdom R; Kung HJ; Luciw PA
J Biol Chem; 2004 Sep; 279(37):38325-30. PubMed ID: 15247271
[TBL] [Abstract] [Full Text] [Related]
17. Infrequent but high-level amplification of 17p11.2 approximately p12 in human glioma.
van Dartel M; Leenstra S; Troost D; Hulsebos TJ
Cancer Genet Cytogenet; 2003 Jan; 140(2):162-6. PubMed ID: 12645656
[TBL] [Abstract] [Full Text] [Related]
