BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Sarcomas AND MYC, c-Myc, 4609, ENSG00000136997
789 results:

  • 1. Design, Synthesis, and Anti-Leukemic Evaluation of a Series of Dianilinopyrimidines by Regulating the Ras/Raf/MEK/ERK and STAT3/c-myc Pathways.
    Wang C; Wang B; Mou Y; Liu X; Chen Q; Pu W; Rao Q; Wang C; Song J; Huang Y; Yan L; Huang L; Li Y
    Molecules; 2024 Apr; 29(7):. PubMed ID: 38611876
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to mycBP and sponging miR-889-3p.
    Zhang Y; Zhan Y; Liu Z; Guo H; Liu D; Chen C
    Biol Direct; 2024 Apr; 19(1):25. PubMed ID: 38570856
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
    Zhou Y; Ray PS; Zhu J; Stein F; Rettel M; Sekaran T; Sahadevan S; Perez-Perri JI; Roth EK; Myklebost O; Meza-Zepeda LA; von Deimling A; Fu C; Brosig AN; Boye K; Nathrath M; Blattmann C; Lehner B; Hentze MW; Kulozik AE
    Nat Commun; 2024 Apr; 15(1):2810. PubMed ID: 38561347
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Polyphyllin I enhances tumor necrosis factor-related apoptosis-inducing ligand-induced inhibition of human osteosarcoma cell growth downregulating the Wnt/β-catenin pathway.
    Junli C; Fulai Z; Xingyuan S; Xiaoping MA; Peng Z; Chujie Z; Binhao S; Wenchao GU; Yongjun W; Yanping Y
    J Tradit Chin Med; 2024 Apr; 44(2):251-259. PubMed ID: 38504531
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Screening for Synergistic Reagents With Pazopanib Against Osteosarcoma Using a Compound Library.
    Yada Y; Asanuma K; Kakimto T; Okuno K; Okamoto T; Iino T; Nakamura T; Sudo A
    Anticancer Res; 2024 Mar; 44(3):1071-1078. PubMed ID: 38423639
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis.
    Prakasam G; Mishra A; Christie A; Miyata J; Carrillo D; Tcheuyap VT; Ye H; Do QN; Wang Y; Reig Torras O; Butti R; Zhong H; Gagan J; Jones KB; Carroll TJ; Modrusan Z; Durinck S; Requena-Komuro MC; Williams NS; Pedrosa I; Wang T; Rakheja D; Kapur P; Brugarolas J
    J Clin Invest; 2024 Feb; 134(7):. PubMed ID: 38386415
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Identifying squalene epoxidase as a metabolic vulnerability in high-risk osteosarcoma using an artificial intelligence-derived prognostic index.
    Wang Y; Ma X; Xu E; Huang Z; Yang C; Zhu K; Dong Y; Zhang C
    Clin Transl Med; 2024 Feb; 14(2):e1586. PubMed ID: 38372422
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1.
    Sun H; Kawano M; Iwasaki T; Itonaga I; Kubota Y; Tsumura H; Tanaka K
    Oncol Res; 2024; 32(3):463-476. PubMed ID: 38370338
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Up-regulation of RAN by MYBL2 maintains osteosarcoma cancer stem-like cells population during heterogeneous tumor generation.
    Gao W; Zhou J; Huang J; Zhang Z; Chen W; Zhang R; Kang T; Liao D; Zhong L
    Cancer Lett; 2024 Apr; 586():216708. PubMed ID: 38336287
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Unraveling T cell exhaustion in the immune microenvironment of osteosarcoma via single-cell RNA transcriptome.
    Cheng D; Zhang Z; Liu D; Mi Z; Tao W; Fu J; Fan H
    Cancer Immunol Immunother; 2024 Jan; 73(2):35. PubMed ID: 38280005
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  • 11. Prognostic characteristics of a six-gene signature based on ssGSEA in sarcoma.
    Liu J; Lu J; Wang G; Gu L; Li W
    Aging (Albany NY); 2024 Jan; 16(2):1536-1554. PubMed ID: 38240704
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. WWOX promotes osteosarcoma development via upregulation of myc.
    Akkawi R; Hidmi O; Haj-Yahia A; Monin J; Diment J; Drier Y; Stein GS; Aqeilan RI
    Cell Death Dis; 2024 Jan; 15(1):13. PubMed ID: 38182577
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  • 13. m
    Zhang D; Guo Q; You K; Zhang Y; Zheng Y; Wei T
    J Orthop Surg Res; 2024 Jan; 19(1):33. PubMed ID: 38178201
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  • 14. Identification and experimental validation of Stearoyl-CoA desaturase is a new drug therapeutic target for osteosarcoma.
    Nie J; He C; Shu Z; Liu N; Zhong Y; Long X; Liu J; Yang F; Liu Z; Huang P
    Eur J Pharmacol; 2024 Jan; 963():176249. PubMed ID: 38070637
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. The Combination of Methioninase and Ethionine Exploits Methionine Addiction to Selectively Eradicate Osteosarcoma Cells and Not Normal Cells and Synergistically Down-regulates the Expression of
    Aoki Y; Kubota Y; Han Q; Masaki N; Obara K; Bouvet M; Chawla SP; Tome Y; Nishida K; Hoffman RM
    Cancer Genomics Proteomics; 2023 Dec; 20(6suppl):679-685. PubMed ID: 38035708
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells.
    Li S; Xue J; Zhang H; Shang G
    J Orthop Surg Res; 2023 Nov; 18(1):910. PubMed ID: 38031136
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Exploring the role of lactylation-related genes in osteosarcoma: A deep dive into prognostic significance and therapeutic potential.
    Sun J; Li Y; Chen R; Xie Y; Wei J; Li B
    Environ Toxicol; 2024 Feb; 39(2):1001-1017. PubMed ID: 38009602
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Genomic and Molecular Characteristics of Ovarian Carcinosarcoma.
    Ramphal K; Hadfield MJ; Bandera CM; Hart J; Dizon DS
    Am J Clin Oncol; 2023 Dec; 46(12):572-576. PubMed ID: 37986208
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses.
    Yang ZQ; Guo LY; Xiao KW; Zhang C; Wu MH; Yan FF; Cai L
    Aging (Albany NY); 2023 Oct; 15(20):11412-11447. PubMed ID: 37874682
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma.
    Kinnaman MD; Zaccaria S; Makohon-Moore A; Arnold B; Levine MF; Gundem G; Arango Ossa JE; Glodzik D; Rodríguez-Sánchez MI; Bouvier N; Li S; Stockfisch E; Dunigan M; Cobbs C; Bhanot UK; You D; Mullen K; Melchor JP; Ortiz MV; O'Donohue TJ; Slotkin EK; Wexler LH; Dela Cruz FS; Hameed MR; Glade Bender JL; Tap WD; Meyers PA; Papaemmanuil E; Kung AL; Iacobuzio-Donahue CA
    Cancer Res; 2023 Nov; 83(22):3796-3812. PubMed ID: 37812025
    [TBL] [Abstract] [Full Text] [Related]  


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