Terms: = Sarcomas AND NTRK1, ENSG00000198400, 4914, P04629, TRK1, MTC, DKFZp781I14186, p140-TrkA, TRKA, TRK AND Treatment
60 results:
1. A recurrent ntrk1 tyrosine kinase domain mutation pair is characteristic in a subset of dedifferentiated liposarcomas.
Lippai Z; Péterfia B; Papp G; Dezső K; Bedics G; Pápai Z; Lamers MH; Kuin RC; Szuhai K; Sápi Z
Eur J Cancer; 2024 May; 202():114005. PubMed ID: 38531265
[TBL] [Abstract] [Full Text] [Related]
2. Primary Ntrk -rearranged Spindle Cell Neoplasm of the Gastrointestinal Tract: A Clinicopathological and Molecular Analysis of 8 Cases.
Gao X; Xu S; Zhu P; Lao IW; Yu L; Wang J
Am J Surg Pathol; 2024 May; 48(5):623-631. PubMed ID: 38525823
[TBL] [Abstract] [Full Text] [Related]
3. Ntrk-rearranged spindle cell sarcoma of the uterine cervix with a novel NUMA1::ntrk1 fusion.
Szalai L; Vereczkey I; Szemes M; Rókusz A; Csernák E; Tóth E; Melegh Z
Virchows Arch; 2024 Mar; 484(3):527-531. PubMed ID: 38151535
[TBL] [Abstract] [Full Text] [Related]
4. Sequential treatments with trk inhibitors in a patient with Ntrk fusion-positive sarcoma: A case report.
Kubota Y; Kawano M; Iwasaki T; Itonaga I; Tsumura H; Kaku N; Tanaka K
Medicine (Baltimore); 2023 Dec; 102(49):e36232. PubMed ID: 38065851
[TBL] [Abstract] [Full Text] [Related]
5. Detection of Novel Tyrosine Kinase Fusion Genes as Potential Therapeutic Targets in Bone and Soft Tissue sarcomas Using DNA/RNA-based Clinical Sequencing.
Hasegawa N; Hayashi T; Niizuma H; Kikuta K; Imanishi J; Endo M; Ikeuchi H; Sasa K; Sano K; Hirabayashi K; Takagi T; Ishijima M; Kato S; Kohsaka S; Saito T; Suehara Y
Clin Orthop Relat Res; 2024 Mar; 482(3):549-563. PubMed ID: 38014853
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6. Identification of dual STRN-Ntrk2 rearrangements in a high grade sarcoma, with good clinical response to first-line larotrectinib therapy.
Lin R; Mallick AB; Wang ZX; Brown SA; Lu B; Jiang W
Diagn Pathol; 2023 Oct; 18(1):116. PubMed ID: 37865792
[TBL] [Abstract] [Full Text] [Related]
7. Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas.
Kummar S; Shen L; Hong DS; McDermott R; Keedy VL; Casanova M; Demetri GD; Dowlati A; Melcón SG; Lassen UN; Leyvraz S; Liu T; Moreno V; Patel J; Patil T; Mallick AB; Sousa N; Tahara M; Ziegler DS; Norenberg R; Arvis P; Brega N; Drilon A; Tan DSW
Cancer; 2023 Dec; 129(23):3772-3782. PubMed ID: 37769113
[TBL] [Abstract] [Full Text] [Related]
8. Therapeutic strategies and clinical evolution of patients with infantile fibrosarcoma: a unique paediatric case series.
Corral Sánchez MD; Jiménez Carrascoso R; Rubio Aparicio P; Plaza López de Sabando D; Sastre Urgelles A; Pozo-Kreilinger JJ; López Gutiérrez JC; Gómez Cervantes M; Ortiz Cruz EJ; Pérez-Martínez A
Clin Transl Oncol; 2023 Nov; 25(11):3307-3311. PubMed ID: 37097530
[TBL] [Abstract] [Full Text] [Related]
9. Intestinal infantile fibrosarcoma with translocation of Ntrk. A case report and review of the literature.
Soler PM; Duque MSR; Juan GM; Terán AKC; Calvo ART; Cobo MLC
Rev Esp Patol; 2023; 56(2):76-81. PubMed ID: 37061245
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10. Natural history and treatment efficacy in an ambispective case series of Ntrk-rearranged mesenchymal tumors.
Dufresne A; Pissaloux D; Ngo C; Penel N; Le Cesne A; Macagno N; Vanacker H; Hénon C; Jean-Denis M; Rughoo K; Tirode F; Blay JY; Brahmi M
ESMO Open; 2023 Apr; 8(2):101202. PubMed ID: 37054503
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11. Nefarious Ntrk oncogenic fusions in pediatric sarcomas: Too many to trk.
Aepala MR; Peiris MN; Jiang Z; Yang W; Meyer AN; Donoghue DJ
Cytokine Growth Factor Rev; 2022 Dec; 68():93-106. PubMed ID: 36153202
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12. Expert consensus on the diagnosis and treatment of Ntrk gene fusion solid tumors in China.
Xu C; Si L; Wang W; Li Z; Song Z; Wang Q; Liu A; Yu J; Fang W; Zhong W; Wang Z; Zhang Y; Liu J; Zhang S; Cai X; Liu A; Li W; Zhan P; Liu H; Lv T; Miao L; Min L; Chen Y; Yuan J; Wang F; Jiang Z; Lin G; Pu X; Lin R; Liu W; Rao C; Lv D; Yu Z; Lei L; Li X; Tang C; Zhou C; Zhang J; Xue J; Guo H; Chu Q; Meng R; Wu J; Zhang R; Hu X; Zhou J; Zhu Z; Li Y; Qiu H; Xia F; Lu Y; Chen X; Ge R; Dai E; Han Y; Pan W; Luo J; Jia H; Dong X; Pang F; Wang K; Wang L; Zhu Y; Xie Y; Lin X; Cai J; Wei J; Lan F; Feng H; Wang L; Du Y; Yao W; Shi X; Niu X; Yuan D; Yao Y; Huang J; Zhang Y; Sun P; Wang H; Ye M; Wang D; Wang Z; Wan B; Lv D; Wei Q; Kang J; Zhang J; Zhang C; Yu G; Ou J; Shi L; Li Z; Liu Z; Liu J; Yang N; Wu L; Wang H; Jin G; Yang L; Wang G; Fang M; Fang Y; Li Y; Wang X; Zhang Y; Ma S; Wang B; Zhang X; Song Y; Lu Y
Thorac Cancer; 2022 Nov; 13(21):3084-3097. PubMed ID: 36127731
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13. A novel Tmtc2-Ntrk3 fusion in undifferentiated high-grade pleomorphic sarcoma.
Bai C; Zhang L; Wang Y; You X; Ju Y; Sun T; Fan Z
J Cancer Res Clin Oncol; 2022 Oct; 148(10):2933-2937. PubMed ID: 35933643
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14. Dramatic response to entrectinib in a patient with malignant peripheral nerve sheath tumor harboring novel SNRNP70-Ntrk3 fusion gene.
Kobayashi H; Makise N; Shinozaki-Ushiku A; Zhang L; Ishibashi Y; Ikegami M; Tsuda Y; Kohsaka S; Ushiku T; Oda K; Miyagawa K; Aburatani H; Mano H; Tanaka S
Genes Chromosomes Cancer; 2023 Jan; 62(1):47-51. PubMed ID: 35906852
[TBL] [Abstract] [Full Text] [Related]
15. Rationale and design of ON-trk: a novel prospective non-interventional study in patients with trk fusion cancer treated with larotrectinib.
Yang JCH; Brose MS; Castro G; Kim ES; Lassen UN; Leyvraz S; Pappo A; López-Ríos F; Reeves JA; Fellous M; Penault-Llorca F; Rudzinski ER; Tabatabai G; Vassal G; Drilon A; Trent J
BMC Cancer; 2022 Jun; 22(1):625. PubMed ID: 35672677
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16.
Siozopoulou V; Marcq E; De Winne K; Norga K; Schmitz G; Duwel V; Delvenne P; Smits E; Pauwels P
Pathol Oncol Res; 2022; 28():1610423. PubMed ID: 35645621
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17. The potential long-term comparative effectiveness of larotrectinib vs standard of care for treatment of metastatic trk fusion thyroid cancer, colorectal cancer, and soft tissue sarcoma.
Suh K; Carlson JJ; Xia F; Williamson T; Sullivan SD
J Manag Care Spec Pharm; 2022 Jun; 28(6):622-630. PubMed ID: 35362337
[No Abstract] [Full Text] [Related]
18. The Use of Pan-Tropomyosin Receptor Kinase Immunohistochemistry as a Screening Tool for the Detection of Neurotrophic Tropomyosin-Related Kinase Fusions: Real-World Data from a National Multicentric Retrospective Study.
Van Bockstal MR; Beniuga G; Craciun L; Creytens D; Dedeurwaerdere F; Delvenne P; Demetter P; De Wiest B; Dewinne K; Habran L; Pauwels P; Theate I; Vander Borght S; Van Der Steen K; Weynand B
Pathobiology; 2022; 89(6):393-406. PubMed ID: 35350025
[TBL] [Abstract] [Full Text] [Related]
19. Mesenchymal neoplasms with Ntrk and other kinase gene alterations.
Davis JL; Al-Ibraheemi A; Rudzinski ER; Surrey LF
Histopathology; 2022 Jan; 80(1):4-18. PubMed ID: 34958503
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20. Novel fusion sarcomas including targetable Ntrk and ALK.
Chen T; Wang Y; Goetz L; Corey Z; Dougher MC; Smith JD; Fox EJ; Freiberg AS; Flemming D; Fanburg-Smith JC
Ann Diagn Pathol; 2021 Oct; 54():151800. PubMed ID: 34464935
[TBL] [Abstract] [Full Text] [Related]
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