BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Sarcomas AND PDGFRA, MGC74795, 5156, ENSG00000134853, PDGFR2, CD140A, Rhe-PDGFRA, CD140a, P16234 AND Prognosis
33 results:

  • 1. Avapritinib-based SAR studies unveil a binding pocket in KIT and pdgfra.
    Teuber A; Schulz T; Fletcher BS; Gontla R; Mühlenberg T; Zischinsky ML; Niggenaber J; Weisner J; Kleinbölting SB; Lategahn J; Sievers S; Müller MP; Bauer S; Rauh D
    Nat Commun; 2024 Jan; 15(1):63. PubMed ID: 38167404
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Clinicopathological and molecular analyses of uterine carcinosarcomas using next-generation sequencing: A single-center experience.
    Erdogan EG; Yalta TD; Can N; Süt N; Taştekin E; Usta U; Puyan FÖ; Usturalı Keskin FE; Kurt BB
    Indian J Pathol Microbiol; 2023; 66(3):449-455. PubMed ID: 37530323
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Intimal Sarcoma with MDM2/CDK4 Amplification and p16 Overexpression: A Review of Histological Features in Primary Tumor and Xenograft, with Immunophenotype and Molecular Profiling.
    Giner F; Machado I; Rubio-Martínez LA; López-Guerrero JA; Claramunt-Alonso R; Navarro S; Ferrández A; Mayordomo-Aranda E; Llombart-Bosch A
    Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108696
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas.
    Brahmi M; Lesluyes T; Dufresne A; Toulmonde M; Italiano A; Mir O; Le Cesne A; Valentin T; Chevreau C; Bonvalot S; Penel N; Coindre JM; Le Guellec S; Le Loarer F; Karanian M; Blay JY; Chibon F
    ESMO Open; 2021 Feb; 6(1):100037. PubMed ID: 33524869
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Avapritinib in unresectable or metastatic pdgfra D842V-mutant gastrointestinal stromal tumours: Long-term efficacy and safety data from the NAVIGATOR phase I trial.
    Jones RL; Serrano C; von Mehren M; George S; Heinrich MC; Kang YK; Schöffski P; Cassier PA; Mir O; Chawla SP; Eskens FALM; Rutkowski P; Tap WD; Zhou T; Roche M; Bauer S
    Eur J Cancer; 2021 Mar; 145():132-142. PubMed ID: 33465704
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. [Clinicopathological characteristics of pulmonary artery intimal sarcoma].
    Wang B; Zhang T; Liu HY; Chen RR; Zhang XY; Zhang HL; Zhai ZG; Zhong DR
    Zhonghua Bing Li Xue Za Zhi; 2021 Jan; 50(1):38-43. PubMed ID: 33396985
    [No Abstract]    [Full Text] [Related]  

  • 7. A genomic survey of sarcomas on sun-exposed skin reveals distinctive candidate drivers and potentially targetable mutations.
    Miller TI; Zoumberos NA; Johnson B; Rhodes DR; Tomlins SA; Chan MP; Andea AA; Lucas DR; McHugh JB; Smith N; Harms KL; Brewer C; Saleh J; Patel RM; Harms PW
    Hum Pathol; 2020 Aug; 102():60-69. PubMed ID: 32540221
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. [Cardiac intimal sarcoma: A case report of a rare tumor with peculiar histopathological findings].
    Nassereddine H; Sciot R; Debiec-Rychter M; Aydin S; Libbrecht L
    Ann Pathol; 2019 Dec; 39(6):440-443. PubMed ID: 31488339
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Clinical Genomic Sequencing of Pediatric and Adult Osteosarcoma Reveals Distinct Molecular Subsets with Potentially Targetable Alterations.
    Suehara Y; Alex D; Bowman A; Middha S; Zehir A; Chakravarty D; Wang L; Jour G; Nafa K; Hayashi T; Jungbluth AA; Frosina D; Slotkin E; Shukla N; Meyers P; Healey JH; Hameed M; Ladanyi M
    Clin Cancer Res; 2019 Nov; 25(21):6346-6356. PubMed ID: 31175097
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Single-Center Experience with Intimal Sarcoma, an Ultra-Orphan, Commonly Fatal Mesenchymal Malignancy.
    Van Dievel J; Sciot R; Delcroix M; Vandeweyer RO; Debiec-Rychter M; Dewaele B; Cornillie J; Van Cann T; Meyns B; Schöffski P
    Oncol Res Treat; 2017; 40(6):353-359. PubMed ID: 28501860
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Clinicopathological and molecular features of a large cohort of gastrointestinal stromal tumors (GISTs) and review of the literature: BRAF mutations in KIT/pdgfra wild-type GISTs are rare events.
    Huss S; Pasternack H; Ihle MA; Merkelbach-Bruse S; Heitkötter B; Hartmann W; Trautmann M; Gevensleben H; Büttner R; Schildhaus HU; Wardelmann E
    Hum Pathol; 2017 Apr; 62():206-214. PubMed ID: 28159677
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Molecular subtypes of gastrointestinal stromal tumor requiring specific treatments.
    Pogorzelski M; Falkenhorst J; Bauer S
    Curr Opin Oncol; 2016 Jul; 28(4):331-7. PubMed ID: 27163723
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Molecular Subtypes of KIT/pdgfra Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic.
    Boikos SA; Pappo AS; Killian JK; LaQuaglia MP; Weldon CB; George S; Trent JC; von Mehren M; Wright JA; Schiffman JD; Raygada M; Pacak K; Meltzer PS; Miettinen MM; Stratakis C; Janeway KA; Helman LJ
    JAMA Oncol; 2016 Jul; 2(7):922-8. PubMed ID: 27011036
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. p.(L576P) -KIT mutation in GIST: Favorable prognosis and sensitive to imatinib?
    Noujaim J; Gonzalez D; Thway K; Jones RL; Judson I
    Cancer Biol Ther; 2016 May; 17(5):543-5. PubMed ID: 26942271
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Parallelism of DOG1 expression with recurrence risk in gastrointestinal stromal tumors bearing KIT or pdgfra mutations.
    Rizzo FM; Palmirotta R; Marzullo A; Resta N; Cives M; Tucci M; Silvestris F
    BMC Cancer; 2016 Feb; 16():87. PubMed ID: 26867653
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. The standard diagnosis, treatment, and follow-up of gastrointestinal stromal tumors based on guidelines.
    Nishida T; Blay JY; Hirota S; Kitagawa Y; Kang YK
    Gastric Cancer; 2016 Jan; 19(1):3-14. PubMed ID: 26276366
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Tumor genotype is an independent prognostic factor in primary gastrointestinal stromal tumors of gastric origin: a european multicenter analysis based on ConticaGIST.
    Wozniak A; Rutkowski P; Schöffski P; Ray-Coquard I; Hostein I; Schildhaus HU; Le Cesne A; Bylina E; Limon J; Blay JY; Siedlecki JA; Wardelmann E; Sciot R; Coindre JM; Debiec-Rychter M
    Clin Cancer Res; 2014 Dec; 20(23):6105-16. PubMed ID: 25294914
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Gastrointestinal stromal tumours: from KIT to succinate dehydrogenase.
    Doyle LA; Hornick JL
    Histopathology; 2014 Jan; 64(1):53-67. PubMed ID: 24117705
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. [Gastrointestinal stromal tumors (GIST): at the forefront of targeted therapies].
    Emile JF
    Med Sci (Paris); 2013; 29(6-7):630-6. PubMed ID: 23859518
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. [Histology and molecular biology of GIST].
    Emile JF
    Bull Acad Natl Med; 2012; 196(4-5):835-44. PubMed ID: 23550446
    [TBL] [Abstract] [Full Text] [Related]  


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