Terms: = Sarcomas AND PDGFRA, MGC74795, 5156, ENSG00000134853, PDGFR2, CD140A, Rhe-PDGFRA, CD140a, P16234 AND Treatment
142 results:
1. KIT/pdgfra inhibitors for the treatment of gastrointestinal stromal tumors: getting to the gist of the problem.
Cicala CM; Olivares-Rivas I; Aguirre-Carrillo JA; Serrano C
Expert Opin Investig Drugs; 2024 Mar; 33(3):159-170. PubMed ID: 38344849
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2. Avapritinib-based SAR studies unveil a binding pocket in KIT and pdgfra.
Teuber A; Schulz T; Fletcher BS; Gontla R; Mühlenberg T; Zischinsky ML; Niggenaber J; Weisner J; Kleinbölting SB; Lategahn J; Sievers S; Müller MP; Bauer S; Rauh D
Nat Commun; 2024 Jan; 15(1):63. PubMed ID: 38167404
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3. Sarcoma care in the era of precision medicine.
Wallander K; Öfverholm I; Boye K; Tsagkozis P; Papakonstantinou A; Lin Y; Haglund de Flon F
J Intern Med; 2023 Dec; 294(6):690-707. PubMed ID: 37643281
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4. REGISTRI: Regorafenib in first-line of KIT/pdgfra wild type metastatic GIST: a collaborative Spanish (GEIS), Italian (ISG) and French Sarcoma Group (FSG) phase II trial.
Martin-Broto J; Valverde C; Hindi N; Vincenzi B; Martinez-Trufero J; Grignani G; Italiano A; Lavernia J; Vallejo A; Tos PD; Le Loarer F; Gonzalez-Campora R; Ramos R; Hernández-Jover D; Gutierrez A; Serrano C; Monteagudo M; Letón R; Robledo M; Moura DS; Martin-Ruiz M; López-Guerrero JA; Cruz J; Fernandez-Serra A; Blay JY; Fumagalli E; Martinez-Marin V
Mol Cancer; 2023 Aug; 22(1):127. PubMed ID: 37559050
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5. A Phase I, Multicenter, Open-Label, First-in-Human Study of DS-6157a in Patients with Advanced Gastrointestinal Stromal Tumor.
George S; Heinrich MC; Somaiah N; Oppelt P; McLeod R; Nishioka S; Kundu MG; Qian X; Kumar P; Laadem A; Lau Y; Tran BP; Fallon M; Dosunmu O; Shi J; Naito Y
Clin Cancer Res; 2023 Sep; 29(18):3659-3667. PubMed ID: 37363962
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6. Molecular Advances in the treatment of Advanced Gastrointestinal Stromal Tumor.
Venkataraman V; George S; Cote GM
Oncologist; 2023 Aug; 28(8):671-681. PubMed ID: 37315115
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7. The multifaceted landscape behind imatinib resistance in gastrointestinal stromal tumors (GISTs): A lesson from ripretinib.
Di Vito A; Ravegnini G; Gorini F; Aasen T; Serrano C; Benuzzi E; Coschina E; Monesmith S; Morroni F; Angelini S; Hrelia P
Pharmacol Ther; 2023 Aug; 248():108475. PubMed ID: 37302758
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8. SEOM-GEIS clinical guideline for gastrointestinal stromal tumors (2022).
Serrano C; Álvarez R; Carrasco JA; Marquina G; Martínez-García J; Martínez-Marín V; Sala MÁ; Sebio A; Sevilla I; Martín-Broto J
Clin Transl Oncol; 2023 Sep; 25(9):2707-2717. PubMed ID: 37129716
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9. LIX1 Controls MAPK Signaling Reactivation and Contributes to GIST-T1 Cell Resistance to Imatinib.
Ruiz-Demoulin S; Trenquier E; Dekkar S; Deshayes S; Boisguérin P; Serrano C; de Santa Barbara P; Faure S
Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108337
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10. Circulating tumor DNA analysis of the phase III VOYAGER trial: KIT mutational landscape and outcomes in patients with advanced gastrointestinal stromal tumor treated with avapritinib or regorafenib.
Serrano C; Bauer S; Gómez-Peregrina D; Kang YK; Jones RL; Rutkowski P; Mir O; Heinrich MC; Tap WD; Newberry K; Grassian A; Shi H; Bialick S; Schöffski P; Pantaleo MA; von Mehren M; Trent JC; George S
Ann Oncol; 2023 Jul; 34(7):615-625. PubMed ID: 37105265
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11. Co-targeting of ACK1 and KIT triggers additive anti-proliferative and -migration effects in imatinib-resistant gastrointestinal stromal tumors.
He W; Xu L; Ding J; Song L; Yang W; Klooster I; Pilco-Janeta DF; Serrano C; Fang H; Jiang G; Wang X; Yu J; Ou WB
Biochim Biophys Acta Mol Basis Dis; 2023 Jun; 1869(5):166690. PubMed ID: 36921738
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12. Patient-reported outcomes in individuals with advanced gastrointestinal stromal tumor treated with ripretinib in the fourth-line setting: analysis from the phase 3 INVICTUS trial.
Schöffski P; George S; Heinrich MC; Zalcberg JR; Bauer S; Gelderblom H; Serrano C; Jones RL; Attia S; D'Amato G; Chi P; Reichardt P; Becker C; Shi K; Meade J; Ruiz-Soto R; Blay JY; von Mehren M
BMC Cancer; 2022 Dec; 22(1):1302. PubMed ID: 36514034
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13. NCCN Guidelines® Insights: Gastrointestinal Stromal Tumors, Version 2.2022.
von Mehren M; Kane JM; Riedel RF; Sicklick JK; Pollack SM; Agulnik M; Bui MM; Carr-Ascher J; Choy E; Connelly M; Dry S; Ganjoo KN; Gonzalez RJ; Holder A; Homsi J; Keedy V; Kelly CM; Kim E; Liebner D; McCarter M; McGarry SV; Mesko NW; Meyer C; Pappo AS; Parkes AM; Petersen IA; Poppe M; Schuetze S; Shabason J; Spraker MB; Zimel M; Bergman MA; Sundar H; Hang LE
J Natl Compr Canc Netw; 2022 Nov; 20(11):1204-1214. PubMed ID: 36351335
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14. KIT-Associated Familial GIST Syndrome: Response to Tyrosine Kinase Inhibitors and Implications for Risk Management.
Brodey A; Kounnis V; Hawkes L; Jones RL; McVeigh TP; Cojocaru E
Oncologist; 2022 Aug; 27(8):615-620. PubMed ID: 35791894
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15. Next questions for the medical treatment of gastrointestinal stromal tumor.
Italiano A
Curr Opin Oncol; 2022 Jul; 34(4):348-353. PubMed ID: 35730519
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16. Primary central nervous system histiocytic sarcoma with somatic
Wang W; Zhang Y; Dong Y; Li S; Qin H
Clin Neuropathol; 2022; 41(6):253-262. PubMed ID: 35652545
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17. The GIST of Advances in treatment of Advanced Gastrointestinal Stromal Tumor.
Schaefer IM; DeMatteo RP; Serrano C
Am Soc Clin Oncol Educ Book; 2022 Apr; 42():1-15. PubMed ID: 35522913
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18. Diagnosing gastrointestinal stromal tumors: The utility of fine-needle aspiration cytology versus biopsy.
Zhang Y; Renberg S; Papakonstantinou A; Haglund de Flon F
Cancer Med; 2022 Jul; 11(14):2729-2734. PubMed ID: 35301817
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19. Differential Diagnosis and Molecular Stratification of Gastrointestinal Stromal Tumors on CT Images Using a Radiomics Approach.
Starmans MPA; Timbergen MJM; Vos M; Renckens M; Grünhagen DJ; van Leenders GJLH; Dwarkasing RS; Willemssen FEJA; Niessen WJ; Verhoef C; Sleijfer S; Visser JJ; Klein S
J Digit Imaging; 2022 Apr; 35(2):127-136. PubMed ID: 35088185
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20. New Tyrosine Kinase Inhibitors for the treatment of Gastrointestinal Stromal Tumors.
Serrano C; Bauer S
Curr Oncol Rep; 2022 Feb; 24(2):151-159. PubMed ID: 35061196
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